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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3251
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pak3
Name: p21 (RAC1) activated kinase 3
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pak3decreases expressionISOPAK3 (Homo sapiens)6480464CTDTretinoin results in decreased expression of PAK3 mRNAPMID:21934132
Pak3multiple interactionsISOPAK3 (Homo sapiens)6480464CTD[Tretinoin co-treated with arsenic trioxide] results in decreased expression of PAK3 mRNAPMID:15894607
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