Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

RGD ID: 737421
Species: Homo sapiens
RGD Object: Gene
Symbol: NR1D2
Name: nuclear receptor subfamily 1 group D member 2
Acc ID: GO:0004879
Term: nuclear receptor activity
Definition: A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytosol, which leads to its translocation to the nucleus.
Definition Source(s): GOC:txnOH-2018, PMID:23457262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR1D2enablesIBAMGI:103076 or MGI:1352463 or MGI:1352464 or MGI:97747 or MGI:97856 or MGI:98742 or MGI:98743 or PANTHER:PTN001182089 or Rarg (Rattus norvegicus) or Ppara (Rattus norvegicus) or Thrb (Rattus norvegicus) or Vdr (Rattus norvegicus) or Nr1h4 (Rattus norvegicus) or Nr1i2 (Rattus norvegicus) or UniProtKB:O62807 or UniProtKB:O75469 or UniProtKB:P10276 or UniProtKB:P10827 or UniProtKB:P10828 or UniProtKB:P11473 or UniProtKB:P37231 or UniProtKB:Q03181 or UniProtKB:Q07869 or UniProtKB:Q13133 or UniProtKB:Q14994 or UniProtKB:Q96RI1 or WB:WBGene00000908 or ZFIN:ZDB-GENE-000210-31 or ZFIN:ZDB-GENE-030903-3 or ZFIN:ZDB-GENE-040718-313 or ZFIN:ZDB-GENE-050410-7 or ZFIN:ZDB-GENE-080403-10 or ZFIN:ZDB-GENE-980526-284 or ZFIN:ZDB-GENE-990415-263 or ZFIN:ZDB-GENE-990415-268150520179GO_Central GO_REF:0000033
NR1D2enablesIEAPANTHER:PTHR24082:SF112150520179TreeGrafter GO_REF:0000118
NR1D2enablesTAS 150520179UniProt PMID:7997240

PMID:7997240
Go Back to source page   Continue to Ontology report