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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69157
Species: Homo sapiens
RGD Object: Gene
Symbol: BTG2
Name: BTG anti-proliferation factor 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BTG2affects expressionISOBtg2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of BTG2 mRNAPMID:34747641
BTG2affects expressionISOBtg2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of BTG2 mRNAPMID:16611356
BTG2increases expressionISOBtg2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of BTG2 mRNAPMID:20959002 PMID:21215274 PMID:23196670 PMID:32109520 PMID:33387578
BTG2increases expressionISOBtg2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of BTG2 mRNAPMID:16962184 PMID:18691609 PMID:32553695
BTG2multiple interactionsISOBtg2 (Rattus norvegicus)6480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of BTG2 mRNA]PMID:23196670
BTG2multiple interactionsISOBtg2 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BTG2 mRNAPMID:17942748
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