GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atf2 | increases phosphorylation | ISO | ATF2 (Homo sapiens) | 6480464 | CTD | hydroquinone results in increased phosphorylation of ATF2 protein | PMID:23288922 PMID:23791922 | Atf2 | multiple interactions | ISO | ATF2 (Homo sapiens) | 6480464 | CTD | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein]; ATF2 protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [ATF2 protein binds to MIR122 promoter]; hydroquinone promotes the reaction [ATF2 protein binds to PPP2CA promoter]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein] | PMID:23288922 PMID:23791922 | | ||||||||||||||||||||||
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