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GENE - TERM ANNOTATION REPORT

RGD ID: 3772
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stat3
Name: signal transducer and activator of transcription 3
Acc ID: GO:0003700
Term: DNA-binding transcription factor activity
Definition: A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
Definition Source(s): GOC:txnOH-2018
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat3enablesISOStat3 (Mus musculus)1624291RGD MGI:5825383 PMID:28065600

MGI:5825383 PMID:28065600
Stat3enablesISOSTAT3 (Homo sapiens)1624291RGD PMID:15653507 PMID:16285960 PMID:17344214 PMID:18782771 PMID:28781374 PMID:7568001 PMID:9535918

PMID:15653507 PMID:16285960 PMID:17344214 PMID:18782771 PMID:28781374 PMID:7568001 PMID:9535918
Stat3 TAS 730023RGD  
Stat3enablesISSUniProtKB:P407631600115UniProtGO_REF:0000024

GO_REF:0000024
Stat3enablesISSUniProtKB:P422271600115UniProtGO_REF:0000024

GO_REF:0000024
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