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GENE - TERM ANNOTATION REPORT

RGD ID: 3673
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Shh
Name: sonic hedgehog signaling molecule
Acc ID: GO:0007224
Term: smoothened signaling pathway
Definition: The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
Definition Source(s): GOC:mah, PMID:15057936, PMID:15205520
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Shhacts_upstream_of_or_withinISOShh (Mus musculus)1624291RGDMGI:108075 MGI:1857796 MGI:1916147 MGI:95728 PMID:10340755 PMID:10375501 PMID:11118883 PMID:15269168 PMID:16611981 PMID:16880529 PMID:17043310 PMID:25639508 PMID:8906787

PMID:10340755 PMID:10375501 PMID:11118883 PMID:15269168 PMID:16611981 PMID:16880529 PMID:17043310 PMID:25639508 PMID:8906787
Shhinvolved_inISOSHH (Homo sapiens)1624291RGD PMID:17850284 PMID:31279575

PMID:17850284 PMID:31279575
Shhinvolved_inISOShh (Mus musculus)1624291RGD MGI:5142377 PMID:11517919

MGI:5142377 PMID:11517919
Shhinvolved_inIBAFB:FBgn0004644 or MGI:94891 or MGI:96533 or MGI:98297 or PANTHER:PTN001726121 or UniProtKB:Q14623 or UniProtKB:Q15465 or UniProtKB:Q98938 or ZFIN:ZDB-GENE-051010-1 or ZFIN:ZDB-GENE-980526-1661600115GO_CentralGO_REF:0000033

GO_REF:0000033
Shhinvolved_inISSUniProtKB:Q622261600115UniProtGO_REF:0000024

GO_REF:0000024
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