GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcc1 | affects activity | ISO | ABCC1 (Homo sapiens) | 6480464 | CTD | Verapamil affects the activity of ABCC1 protein | PMID:9334814 | Abcc1 | decreases activity | ISO | ABCC1 (Homo sapiens) | 6480464 | CTD | Verapamil results in decreased activity of ABCC1 protein | PMID:15044619 PMID:15451006 | Abcc1 | multiple interactions | ISO | Abcc1 (Mus musculus) | 6480464 | CTD | Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Daunorubicin]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide] | PMID:10856430 | Abcc1 | multiple interactions | ISO | ABCC1 (Homo sapiens) | 6480464 | CTD | Verapamil inhibits the reaction [ABCC1 protein affects the export of 5-carboxyfluorescein diacetate]; Verapamil inhibits the reaction [ABCC1 protein affects the export of Daunorubicin]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]; Verapamil promotes the reaction [ABCC1 protein affects the export of Glutathione]; Verapamil promotes the reaction [ABCC1 protein affects the transport of Glutathione]; Verapamil promotes the reaction [ABCC1 protein results in increased uptake of Glutathione] | PMID:11278867 PMID:12485947 PMID:15498506 PMID:16101123 PMID:16636798 PMID:7954421 | |
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