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GENE - TERM ANNOTATION REPORT

RGD ID: 2123
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apc
Name: APC regulator of WNT signaling pathway
Acc ID: DOID:687
Term: hepatoblastoma
Definition: A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)
Definition Source(s): MESH:D018197
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apc ISOAPC (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: HepatoblastomaPMID:1316610 PMID:15311282 PMID:17293347 PMID:20685668 PMID:22135120 PMID:27081525 PMID:28492532 PMID:35495172 PMID:8381579 PMID:8764128 PMID:9824584
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