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GENE - TERM ANNOTATION REPORT

RGD ID: 2053
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase 1
Acc ID: GO:0035861
Term: site of double-strand break
Definition: A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
Definition Source(s): GOC:bf, GOC:mah, GOC:vw, PMID:20096808, PMID:21035408
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1is_active_inISOPARP1 (Homo sapiens)1624291RGD PMID:29234005

PMID:29234005
Parp1located_inISOPARP1 (Homo sapiens)1624291RGD PMID:26344098 PMID:27568560 PMID:30356214

PMID:26344098 PMID:27568560 PMID:30356214
Parp1is_active_inISSUniProtKB:P098741600115UniProtGO_REF:0000024

GO_REF:0000024
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