GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PARP1 | increases cleavage | ISO | Parp1 (Rattus norvegicus) | 6480464 | CTD | 7-ketocholesterol results in increased cleavage of PARP1 protein | PMID:25845326 | PARP1 | multiple interactions | ISO | Parp1 (Rattus norvegicus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]; BAY 11-7085 inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]; quercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein] | PMID:25845326 | |
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