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GENE - TERM ANNOTATION REPORT

RGD ID: 1313111
Species: Mus musculus
RGD Object: Gene
Symbol: Sirt6
Name: sirtuin 6
Acc ID: GO:0046969
Term: NAD-dependent histone H3K9 deacetylase activity
Definition: Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.
Definition Source(s): PMID:28450737
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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