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GENE - TERM ANNOTATION REPORT

RGD ID: 12514168
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Map3k1
Name: mitogen-activated protein kinase kinase kinase 1
Acc ID: PW:0000102
Term: the extracellular signal-regulated Raf/Mek/Erk signaling pathway
Definition: The Raf/Mek/Erk signaling pathway - a Ras activated protein kinase cascade - regulates diverse processes such as cell growth, proliferation and differentiation, in response to cytokines, hormones, growth factors.
Definition Source(s): GO:0070371, KEGG:map04010, PMID:15035987, PMID:17112607, PMID:17229475, PMID:17306385
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k1 ISOMAP3K1 (Homo sapiens)9068941RGD PMID:12835716 PMID:9305638 REF_RGD_ID:1357969 REF_RGD_ID:2293879
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