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GENE - TERM ANNOTATION REPORT

RGD ID: 12252074
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: NPPA
Name: natriuretic peptide A
Acc ID: DOID:9004616
Term: Left Ventricular Hypertrophy
Definition: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
Definition Source(s): MESH:D017379
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NPPA ISONppa (Rattus norvegicus)9068941RGDassociated with Kidney Failure, Chronic;mRNA:increased expression:heartPMID:24013683 REF_RGD_ID:7297044
NPPA ISONppa (Rattus norvegicus)9068941RGDmRNA:increased expression:heart left ventriclePMID:16272201 REF_RGD_ID:1580154
NPPA ISONPPA (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:10755198 PMID:9455993
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