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GENE - TERM ANNOTATION REPORT

RGD ID: 11772177
Species: Pan paniscus
RGD Object: Gene
Symbol: KCNJ11
Name: potassium inwardly rectifying channel subfamily J member 11
Acc ID: GO:0015272
Term: ATP-activated inward rectifier potassium channel activity
Definition: Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.
Definition Source(s): GOC:cb, GOC:mah
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KCNJ11 ISOKcnj11 (Rattus norvegicus)9068941RGD PMID:15163199 PMID:17097686 REF_RGD_ID:1598646 REF_RGD_ID:1625274
KCNJ11enablesIEAUniProtKB:Q61743 or ensembl:ENSMUSP00000147439150520179Ensembl GO_REF:0000107
KCNJ11enablesIEAInterPro:IPR003279150520179InterPro GO_REF:0000002
KCNJ11enablesIEAPANTHER:PTHR11767:SF44150520179TreeGrafter GO_REF:0000118
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