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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal dentin development
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Accession:MP:0030542 term browser browse the term
Definition:any anomaly in the process whose specific outcome is the formation of dentin, the hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root; dentinogenesis begins prior to enamel formation and is initiated by the odontoblasts of the dental pulp; dentin is derived from the dental papilla of the tooth germ; after apposition of predentin and maturation into dentin, the cell bodies of the odontoblasts remain in the pulp inside the tooth, along its outer wall; unlike enamel, dentin continues to form throughout life and can be initiated in response to stimuli, such as tooth decay or attrition
Synonyms:exact_synonym: abnormal dentin formation;   abnormal dentine development;   abnormal dentine formation;   abnormal dentinogenesis


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abnormal dentin development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4930453N24Rik RIKEN cDNA 4930453N24 gene IAGP MGI PMID:8830097 NCBI chr16:64,583,267...64,592,735
Ensembl chr16:64,572,114...64,591,524 		JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 IAGP MGI PMID:21051554 NCBI chr 2:26,483,069...26,494,429
Ensembl chr 2:26,483,069...26,494,429 		JBrowse link
G Dmp1 dentin matrix protein 1 IAGP MGI PMID:14966118 NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase IAGP MGI PMID:22732358 NCBI chr 5:138,740,836...138,795,818
Ensembl chr 5:138,740,269...138,795,832 		JBrowse link
G Notum notum palmitoleoyl-protein carboxylesterase IAGP MGI PMID:26926082 NCBI chr11:120,544,614...120,552,019
Ensembl chr11:120,544,614...120,552,001 		JBrowse link
G Pax9 paired box 9 IAGP MGI PMID:16236760 NCBI chr12:56,738,478...56,759,609
Ensembl chr12:56,738,552...56,759,607 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3, neutral IAGP MGI PMID:16025116 NCBI chr 8:106,979,180...107,064,597
Ensembl chr 8:106,979,180...107,064,620 		JBrowse link
G Sp3 trans-acting transcription factor 3 IAGP MGI PMID:10675334 NCBI chr 2:72,766,774...72,810,790
Ensembl chr 2:72,766,771...72,810,790 		JBrowse link
G Tnn tenascin N IAGP MGI PMID:33552067 NCBI chr 1:159,912,599...159,981,242
Ensembl chr 1:159,912,599...159,981,150 		JBrowse link
abnormal dentin mineralization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, liver/bone/kidney IAGP MGI PMID:22991301 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695 		JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) IAGP MGI PMID:21958845 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785 		JBrowse link
G Dmp1 dentin matrix protein 1 IAGP MGI PMID:14966118 NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968 		JBrowse link
G Dspp dentin sialophosphoprotein IAGP MGI PMID:12721295 NCBI chr 5:104,318,569...104,327,993
Ensembl chr 5:104,318,578...104,327,993 		JBrowse link
G Ostm1 osteopetrosis associated transmembrane protein 1 IEA MGI NCBI chr10:42,554,912...42,578,458
Ensembl chr10:42,459,818...42,578,455 		JBrowse link
G Postn periostin, osteoblast specific factor IAGP MGI PMID:16314533 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458 		JBrowse link
G Ssu2 ssu-2 homolog IAGP MGI PMID:27680507 NCBI chr 6:112,336,283...112,365,160
Ensembl chr 6:112,336,285...112,364,984 		JBrowse link
G Wnt10a wingless-type MMTV integration site family, member 10A IAGP MGI PMID:25629078 NCBI chr 1:74,831,178...74,843,335
Ensembl chr 1:74,830,675...74,843,338 		JBrowse link
abnormal odontoblast differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prrx1 paired related homeobox 1 IAGP MGI PMID:9876178 NCBI chr 1:163,072,688...163,142,714
Ensembl chr 1:163,072,688...163,141,279 		JBrowse link
G Prrx2 paired related homeobox 2 IAGP MGI PMID:9876178 NCBI chr 2:30,735,076...30,771,263
Ensembl chr 2:30,724,984...30,771,263 		JBrowse link
G Tnn tenascin N IAGP MGI PMID:33552067 NCBI chr 1:159,912,599...159,981,242
Ensembl chr 1:159,912,599...159,981,150 		JBrowse link
abnormal odontoblast morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, liver/bone/kidney IAGP MGI PMID:22991301 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695 		JBrowse link
G Bcl11b B cell leukemia/lymphoma 11B IAGP MGI PMID:19251658 NCBI chr12:107,876,662...107,970,404
Ensembl chr12:107,876,662...107,969,861 		JBrowse link
G Cpne7 copine VII IAGP MGI PMID:38105557 NCBI chr 8:123,844,054...123,861,924
Ensembl chr 8:123,844,113...123,861,921 		JBrowse link
G Irx1 Iroquois homeobox 1 IAGP MGI PMID:28746823 NCBI chr13:72,106,351...72,111,842
Ensembl chr13:72,106,040...72,111,842 		JBrowse link
G Notum notum palmitoleoyl-protein carboxylesterase IAGP MGI PMID:26926082 NCBI chr11:120,544,614...120,552,019
Ensembl chr11:120,544,614...120,552,001 		JBrowse link
G Pthlh parathyroid hormone-like peptide IAGP MGI PMID:9391087 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681 		JBrowse link
G Shh sonic hedgehog IAGP MGI PMID:11044393 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
abnormal predentin morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1 colony stimulating factor 1 (macrophage) IAGP MGI PMID:21958845 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785 		JBrowse link
G Dmp1 dentin matrix protein 1 IAGP MGI PMID:14966118 NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968 		JBrowse link
G Dspp dentin sialophosphoprotein IAGP MGI PMID:12721295 NCBI chr 5:104,318,569...104,327,993
Ensembl chr 5:104,318,578...104,327,993 		JBrowse link
G Ssu2 ssu-2 homolog IAGP MGI PMID:27680507 NCBI chr 6:112,336,283...112,365,160
Ensembl chr 6:112,336,285...112,364,984 		JBrowse link
G Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 IAGP MGI PMID:3998439 NCBI chr19:3,946,050...3,957,717
Ensembl chr19:3,946,050...3,957,133 		JBrowse link
increased odontoblast number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ssu2 ssu-2 homolog IAGP MGI PMID:27680507 NCBI chr 6:112,336,283...112,365,160
Ensembl chr 6:112,336,285...112,364,984 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16883
    craniofacial phenotype 1638
      abnormal craniofacial morphology 1638
        abnormal craniofacial development 527
          abnormal tooth development 130
            abnormal dentin development 24
              abnormal dentin mineralization 8
              abnormal odontoblast morphology + 11
              abnormal predentin morphology 5
Path 2
Term Annotations click to browse term
  mammalian phenotype 16883
    skeleton phenotype 3367
      abnormal skeleton morphology 3178
        abnormal axial skeleton morphology 1782
          abnormal craniofacial bone morphology 1036
            abnormal cranium morphology 1020
              abnormal viscerocranium morphology 756
                abnormal jaw morphology 684
                  abnormal dental arch morphology 362
                    abnormal tooth morphology 361
                      abnormal tooth hard tissue morphology 74
                        abnormal dentin morphology 31
                          abnormal dentin development 24
                            abnormal dentin mineralization 8
                            abnormal odontoblast morphology + 11
                            abnormal predentin morphology 5
paths to the root