canonical Wnt signaling pathway involved in heart development - Ontology Report

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Term:	canonical Wnt signaling pathway involved in heart development	go back to main search page
Accession:	GO:0061316	browse the term
Definition:	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Synonyms:	exact_synonym:	canonical Wnt receptor signaling pathway involved in heart development; canonical Wnt receptor signalling pathway involved in heart development; canonical Wnt-activated signaling pathway involved in heart development

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Term paths to the root

Path 1
Term	Annotations
biological_process	19670
cellular process	18301
signal transduction	6575
cell surface receptor signaling pathway	3202
cell surface receptor signaling pathway involved in heart development	9
Wnt signaling pathway involved in heart development	4
canonical Wnt signaling pathway involved in heart development	0
Path 2
Term	Annotations
biological_process	19670
developmental process	7619
anatomical structure development	7030
multicellular organism development	5642
system development	4920
circulatory system development	1474
heart development	783
cell surface receptor signaling pathway involved in heart development	9
Wnt signaling pathway involved in heart development	4
canonical Wnt signaling pathway involved in heart development	0

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