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Pathways
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Ontology Browser
Term:
canonical Wnt signaling pathway involved in heart development (GO:0061316)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
beta-catenin destruction complex disassembly  
canonical Wnt signaling pathway involved in heart development 
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation  
canonical Wnt signaling pathway involved in negative regulation of apoptotic process  
canonical Wnt signaling pathway involved in positive regulation of apoptotic process  
negative regulation of canonical Wnt signaling pathway  
negative regulation of Wnt signaling pathway involved in heart development +   
non-canonical Wnt signaling pathway involved in heart development +   
positive regulation of canonical Wnt signaling pathway  
receptor internalization involved in canonical Wnt signaling pathway 
regulation of canonical Wnt signaling pathway +   
regulation of Wnt signaling pathway involved in heart development +   

Synonyms
Exact Synonyms: canonical Wnt receptor signaling pathway involved in heart development ;   canonical Wnt receptor signalling pathway involved in heart development ;   canonical Wnt-activated signaling pathway involved in heart development
Definition Sources: GOC:mtg_heart

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