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ONTOLOGY REPORT - ANNOTATIONS


Term:lymph node development
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Accession:GO:0048535 term browser browse the term
Definition:The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.
Synonyms:broad_synonym: lymph gland development



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lymph node development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl21 C-C motif chemokine ligand 21 acts_upstream_of_or_within ISO MGI:1857881 (PMID:12732660) RGD PMID:12732660 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686
JBrowse link
G Cd248 CD248 molecule acts_upstream_of_or_within ISO MGI:3625491 (PMID:20432232) RGD PMID:20432232 NCBI chr 1:202,373,676...202,376,240
Ensembl chr 1:202,373,676...202,376,240
JBrowse link
G Cd2ap CD2-associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2664945 (PMID:24218450)
Ensembl
RGD
PMID:24218450 GO_REF:0000107 NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 involved_in
acts_upstream_of_or_within
ISO (MGI:4436841|PMID:19783990)
MGI:2384500 (PMID:12732660)
RGD PMID:12732660 PMID:19783990 MGI:4436841 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2158677 (PMID:12732660)
Ensembl
RGD
PMID:12732660 GO_REF:0000107 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
JBrowse link
G Fadd Fas associated via death domain involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q9QZL0 (MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:3628823 (PMID:20457904) RGD PMID:20457904 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO MGI:2158738 (PMID:7923373) RGD PMID:7923373 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Il15 interleukin 15 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2136897 (PMID:10704459)
Ensembl
RGD
PMID:10704459 GO_REF:0000107 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (PMID:12732660) RGD PMID:12732660 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Lta lymphotoxin alpha acts_upstream_of_or_within ISO MGI:1857215|MGI:1860953|MGI:1860954|MGI:1860957 (PMID:10415063), (PMID:7636227), (PMID:8171322), (PMID:9368616), (PMID:9565643) RGD PMID:7636227 PMID:8171322 PMID:9368616 PMID:9565643 PMID:10415063 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Ltb lymphotoxin beta acts_upstream_of_or_within ISO MGI:1860955|MGI:1860970 (PMID:9133428), (PMID:9256477) RGD PMID:9133428 PMID:9256477 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Nkx2-3 NK2 homeobox 3 acts_upstream_of_or_within ISO MGI:2386680|MGI:2448069 (PMID:10790368), (PMID:10926756) RGD PMID:10790368 PMID:10926756 NCBI chr 1:242,478,130...242,481,083
Ensembl chr 1:242,478,130...242,481,083
JBrowse link
G Pdpn podoplanin involved_in ISO
ISS
(MGI:5644359|PMID:25347465)
GO_REF:0000024
RGD
UniProt
PMID:25347465 GO_REF:0000024 MGI:5644359 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO MGI:5427084 (PMID:24388753) RGD PMID:24388753 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within ISO MGI:2442789 (PMID:23583643) RGD PMID:23583643 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 acts_upstream_of_or_within ISO MGI:2685397 (PMID:23583643) RGD PMID:23583643 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933
JBrowse link
G Rcbtb2 RCC1 and BTB domain containing protein 2 acts_upstream_of_or_within ISO (PMID:26291700) RGD PMID:26291700 NCBI chr15:48,319,809...48,364,441
Ensembl chr15:48,323,866...48,383,750
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q61160 (MGI:5291865|PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Rorc RAR-related orphan receptor C acts_upstream_of_or_within ISO MGI:3026635 (PMID:14691482) RGD PMID:14691482 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Spns2 SPNS lysolipid transporter 2, sphingosine-1-phosphate acts_upstream_of_or_within ISO MGI:4460276 (PMID:23180825) RGD PMID:23180825 NCBI chr10:57,067,348...57,105,969
Ensembl chr10:57,066,897...57,105,957
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (PMID:1436033) RGD PMID:1436033 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1860238 (PMID:10500098)
GO_Central
RGD
PMID:10500098 GO_REF:0000033 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
JBrowse link
G Tox thymocyte selection-associated high mobility group box acts_upstream_of_or_within ISO MGI:3773716 (PMID:20818394) RGD PMID:20818394 NCBI chr 5:19,874,994...20,171,272
Ensembl chr 5:19,874,467...20,171,272
JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:3510784 (PMID:22585710) RGD PMID:22585710 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      immune system development 234
        hematopoietic or lymphoid organ development 127
          lymph node development 25
Path 2
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      anatomical structure development 6575
        multicellular organism development 5290
          system development 4576
            immune system development 234
              hematopoietic or lymphoid organ development 127
                lymph node development 25
paths to the root