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ONTOLOGY REPORT - ANNOTATIONS

Term:monoatomic ion-gated channel activity
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Accession:GO:0022839 term browser browse the term
Definition:Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.
Synonyms:broad_synonym: ion gated channel activity


show annotations for term's descendants           Sort by:
monoatomic ion-gated channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic1 acid sensing ion channel subunit 1 enables ISO MGI:2179834 (PMID:14960591) RGD PMID:14960591 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Asic2 acid sensing ion channel subunit 2 enables IEA
ISO		 GO_REF:0000107
MGI:2180111 (PMID:14960591)		 Ensembl
RGD		 PMID:14960591 GO_REF:0000107 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987 		JBrowse link
calcium-activated cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1 enables ISO (PMID:22946059) RGD PMID:22946059 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069 		JBrowse link
G Ano10 anoctamin 10 enables ISO (PMID:22946059) RGD PMID:22946059 NCBI chr 8:121,841,664...121,960,739
Ensembl chr 8:121,841,665...121,962,670 		JBrowse link
G Ano6 anoctamin 6 enables ISO (PMID:22946059), (PMID:25651887)
(MGI:5440105|PMID:23021219)		 RGD PMID:22946059 PMID:23021219 PMID:25651887 MGI:5440105 NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589 		JBrowse link
G Calhm1 calcium homeostasis modulator 1 enables ISO (PMID:22711817) RGD PMID:22711817 NCBI chr 1:246,030,269...246,032,988
Ensembl chr 1:246,030,269...246,032,988 		JBrowse link
G Catsper1 cation channel, sperm associated 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:202,643,009...202,652,059
Ensembl chr 1:202,643,038...202,651,824 		JBrowse link
G Catsper2 cation channel, sperm associated 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:108,368,654...108,389,380
Ensembl chr 3:108,368,668...108,388,050 		JBrowse link
G Catsper4 cation channel, sperm associated 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:146,427,682...146,447,346
Ensembl chr 5:146,427,683...146,446,942 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel enables ISO (PMID:10517637), (PMID:11959145) RGD PMID:10517637 PMID:11959145 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Tmem63a transmembrane protein 63a enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:92,662,872...92,696,186
Ensembl chr13:92,663,968...92,696,183 		JBrowse link
G Tmem63b transmembrane protein 63B enables ISO
IBA		 (MGI:6378298|PMID:31243992)
GO_REF:0000033		 RGD
GO_Central		 PMID:31243992 GO_REF:0000033 MGI:6378298 NCBI chr 9:15,313,867...15,340,722
Ensembl chr 9:15,320,432...15,340,720 		JBrowse link
G Tmem63c transmembrane protein 63c enables ISO
IBA
IEA		 (PMID:24503647)
GO_REF:0000033
GO_REF:0000002		 RGD
GO_Central
InterPro		 PMID:24503647 GO_REF:0000002 GO_REF:0000033 NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 IDA RGD PMID:10984475 RGD:61774 NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 enables ISO
IBA
IEA
IDA		 (PMID:27207958), (PMID:29211723)
GO_REF:0000033
GO_REF:0000107
(MGI:4839447|PMID:17188667), (MGI:6119829|PMID:29211714)
PMID:19945433		 RGD
GO_Central
Ensembl		 PMID:17188667 PMID:27207958 PMID:29211714 PMID:29211723 PMID:19945433 GO_REF:0000033 GO_REF:0000107 MGI:4839447 MGI:6119829, RGD:8553249 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
G Trpm5 transient receptor potential cation channel, subfamily M, member 5 enables IBA
ISO		 GO_REF:0000033
(PMID:14657398)		 GO_Central
RGD		 PMID:14657398 GO_REF:0000033 NCBI chr 1:198,254,956...198,277,824
Ensembl chr 1:198,255,723...198,277,654 		JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 TAS RGD PMID:12138163 RGD:634425 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017 		JBrowse link
calcium-activated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk18 potassium two pore domain channel subfamily K member 18 enables ISO (MGI:4839430|PMID:20006580), (PMID:14981085) RGD PMID:14981085 PMID:20006580 MGI:4839430 NCBI chr 1:258,374,671...258,388,945
Ensembl chr 1:258,374,671...258,388,945 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 enables IDA
IMP
ISO
TAS		 PMID:10651830
PMID:16166559
PMID:9403560
(PMID:8897882)
MGI:1334203|MGI:1913272|MGI:3053849 (PMID:10517674), (PMID:12388098), (PMID:15184377), (PMID:16306267), (PMID:17303127), (PMID:7687074)
Reactome:R-RNO-9667806
(PMID:11880513)
(PMID:7993625)
(PMID:11245614), (PMID:17706472), (PMID:18458941), (PMID:7573516), (PMID:7877450)		 RGD
Reactome		 PMID:7573516 PMID:7687074 PMID:7877450 PMID:7993625 PMID:8897882 More... Reactome:R-RNO-9667806, RGD:633136, RGD:633139, RGD:405650292, RGD:405650221 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 enables IBA
ISO		 GO_REF:0000033
MGI:99923 (PMID:12388098)		 GO_Central
RGD		 PMID:12388098 GO_REF:0000033 NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798 		JBrowse link
G Kcnmb2 potassium calcium-activated channel subfamily M regulatory beta subunit 2 enables ISO
IBA
IEA		 (PMID:10692449)
GO_REF:0000033
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:10692449 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:114,670,027...114,975,374
Ensembl chr 2:114,935,976...114,975,173 		JBrowse link
G Kcnmb3 potassium calcium-activated channel subfamily M regulatory beta subunit 3 enables ISO
IBA
IEA		 (PMID:10692449)
GO_REF:0000033
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:10692449 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:115,255,788...115,270,142
Ensembl chr 2:115,253,761...115,270,142 		JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 enables ISS
ISO
IBA		 GO_REF:0000024
MGI:99923 (PMID:12388098)
GO_REF:0000033
(PMID:10692449)		 UniProt
RGD
GO_Central		 PMID:10692449 PMID:12388098 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:52,066,145...52,119,098
Ensembl chr 7:52,066,136...52,119,278 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 enables ISO (PMID:17110593) RGD PMID:17110593 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 enables ISO (PMID:18796614), (PMID:26148990)
(PMID:11724775), (PMID:12388098)		 RGD PMID:11724775 PMID:12388098 PMID:18796614 PMID:26148990 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel enables ISO
IBA		 (PMID:10517637)
GO_REF:0000033		 RGD
GO_Central		 PMID:10517637 GO_REF:0000033 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
chloride-activated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnt1 potassium sodium-activated channel subfamily T member 1 enables IDA PMID:14684870 UniProt PMID:14684870 RGD:1299633 NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667 		JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 enables IMP
IEA
ISO		 PMID:29069600
GO_REF:0000107
(PMID:14684870), (PMID:29069600)		 Ensembl
RGD		 PMID:14684870 PMID:29069600 PMID:29069600 GO_REF:0000107, RGD:13792534 NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987 		JBrowse link
intermediate conductance calcium-activated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnn4 potassium calcium-activated channel subfamily N member 4 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:10532960 PMID:12606302 PMID:20616305 PMID:21868633 GO_REF:0000033, RGD:633066, RGD:7175510, RGD:7175508, RGD:7175507 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
intracellular sodium-activated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnt1 potassium sodium-activated channel subfamily T member 1 enables IBA
IDA		 GO_REF:0000033
PMID:14684870		 GO_Central PMID:14684870 GO_REF:0000033, RGD:1299633 NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667 		JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 enables TAS
ISO
IBA		 (PMID:14684870)
GO_REF:0000033		 RGD
GO_Central		 PMID:14684870 PMID:14684870 GO_REF:0000033, RGD:1299633 NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987 		JBrowse link
large conductance calcium-activated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 enables IDA
ISO
IEA
IBA		 (PMID:7993625)
(PMID:15703204)
GO_REF:0000107
GO_REF:0000033
MGI:3053849 (MGI:5560378|PMID:24602615), (PMID:12388098), (PMID:16873365)		 RGD
Ensembl
GO_Central		 PMID:7993625 PMID:12388098 PMID:15703204 PMID:16873365 PMID:24602615 More... GO_REF:0000033 GO_REF:0000107 MGI:5560378, RGD:7205477 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Kcnu1 potassium calcium-activated channel subfamily U member 1 NOT|enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:66,141,696...66,229,493
Ensembl chr16:66,141,976...66,229,465 		JBrowse link
small conductance calcium-activated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnn1 potassium calcium-activated channel subfamily N member 1 enables IMP
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000002
GO_REF:0000107
(PMID:12382077)		 GO_Central
InterPro
Ensembl
RGD		 PMID:12382077 PMID:19969350 PMID:14559917 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:8693687, RGD:1358336 NCBI chr16:18,574,858...18,598,585
Ensembl chr16:18,585,992...18,597,482 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 enables IMP
IBA
IEA
ISO
IDA		 GO_REF:0000033
GO_REF:0000002
(PMID:12382077), (PMID:19815520), (PMID:24951510)
(MGI:4366185|PMID:19815520), (MGI:5292192|PMID:19139040)
PMID:11323678		 GO_Central
InterPro
RGD		 PMID:12382077 PMID:19139040 PMID:19815520 PMID:24951510 PMID:19969350 More... GO_REF:0000002 GO_REF:0000033 MGI:4366185 MGI:5292192, RGD:8693687, RGD:8554362, RGD:1358336, RGD:7205441, RGD:7205439 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Kcnn3 potassium calcium-activated channel subfamily N member 3 enables IMP
IBA
ISO
IEA		 GO_REF:0000033
(PMID:12382077), (PMID:31155282)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:12382077 PMID:31155282 PMID:14559917 PMID:17459146 PMID:19969350 More... GO_REF:0000033 GO_REF:0000107, RGD:1358336, RGD:7175515, RGD:8693687, RGD:729217, RGD:727322 NCBI chr 2:174,929,846...175,088,910
Ensembl chr 2:174,936,629...175,081,145 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20488
    transporter activity 1237
      transmembrane transporter activity 1143
        passive transmembrane transporter activity 507
          channel activity 507
            gated channel activity 331
              ligand-gated channel activity 187
                monoatomic ion-gated channel activity 30
                  calcium-activated cation channel activity + 26
                  chloride-activated potassium channel activity 2
                  intracellular sodium-activated potassium channel activity 2
paths to the root