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ONTOLOGY REPORT - ANNOTATIONS


Term:channel inhibitor activity
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Accession:GO:0016248 term browser browse the term
Definition:Binds to and stops, prevents, or reduces the activity of a channel.


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channel inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2 apoptosis regulator enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
JBrowse link
G Slc15a1 solute carrier family 15 member 1 ISO short form from pineal gland inhibits transmembrane transport of dipeptides by long form RGD PMID:15684415 RGD:2302143 NCBI chrNW_004936472:11,669,206...11,716,303
Ensembl chrNW_004936472:11,669,206...11,716,303
JBrowse link
calcium channel inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:17,580,425...17,588,480
Ensembl chrNW_004936488:17,580,454...17,588,507
JBrowse link
G Calm2 calmodulin 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:5,207,909...5,223,780
Ensembl chrNW_004936508:5,207,904...5,223,780
JBrowse link
G Calm3 calmodulin 3 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:471,446...480,858
Ensembl chrNW_004936664:471,440...480,441
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:7,916,002...7,922,747
Ensembl chrNW_004936493:7,916,002...7,922,796
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936577:3,896,455...4,198,396
Ensembl chrNW_004936577:3,896,390...4,198,411
JBrowse link
G Mcub mitochondrial calcium uniporter dominant negative subunit beta enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936563:787,104...912,424
Ensembl chrNW_004936563:787,100...911,612
JBrowse link
G Micu1 mitochondrial calcium uptake 1 enables ISO (PMID:32494073), (PMID:37036971), (PMID:37126688) UniProt PMID:32494073 PMID:37036971 PMID:37126688 NCBI chrNW_004936521:6,400,849...6,576,304
Ensembl chrNW_004936521:6,400,804...6,577,134
JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:1,988,839...1,995,597
Ensembl chrNW_004936562:1,989,662...1,995,580
JBrowse link
G Phpt1 phosphohistidine phosphatase 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:1,065,901...1,067,214
Ensembl chrNW_004936669:1,065,900...1,067,214
JBrowse link
G Slc30a1 solute carrier family 30 member 1 enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936557:1,789,263...1,796,548
Ensembl chrNW_004936557:1,789,263...1,796,541
JBrowse link
G Stx1a syntaxin 1A enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:2,909,560...2,918,175
Ensembl chrNW_004936543:2,909,552...2,918,770
JBrowse link
G Tnni3 troponin I3, cardiac type enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936886:437,754...440,925
Ensembl chrNW_004936886:437,754...440,458
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon enables ISO (PMID:18029012) ARUK-UCL PMID:18029012 NCBI chrNW_004936538:7,518,283...7,558,458
Ensembl chrNW_004936538:7,517,271...7,558,854
JBrowse link
chloride channel inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano9 anoctamin 9 enables ISO (PMID:22946059) UniProt PMID:22946059 NCBI chrNW_004936888:289,309...306,184
Ensembl chrNW_004936888:289,868...302,449
JBrowse link
G Cftr CF transmembrane conductance regulator enables ISO (PMID:22178883) UniProt PMID:22178883 NCBI chrNW_004936589:1,565,933...1,719,208 JBrowse link
G Stx1a syntaxin 1A enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:2,909,560...2,918,175
Ensembl chrNW_004936543:2,909,552...2,918,770
JBrowse link
G Stx7 syntaxin 7 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936560:464,667...512,322
Ensembl chrNW_004936560:464,617...513,009
JBrowse link
G Stx8 syntaxin 8 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:2,328,763...2,578,788
Ensembl chrNW_004936595:2,328,740...2,578,791
JBrowse link
G Vamp8 vesicle associated membrane protein 8 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936712:1,688,126...1,689,742
Ensembl chrNW_004936712:1,688,093...1,689,816
JBrowse link
G Vti1b vesicle transport through interaction with t-SNAREs 1B enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936495:11,043,813...11,064,113
Ensembl chrNW_004936495:11,045,429...11,064,206
JBrowse link
inward rectifier potassium channel inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936589:2,504,235...2,536,778
Ensembl chrNW_004936589:2,504,224...2,537,170
JBrowse link
ion channel inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamp1 lysosomal associated membrane protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:377,359...389,121
Ensembl chrNW_004936472:378,173...389,381
JBrowse link
G Lamp2 lysosomal associated membrane protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:9,584,221...9,622,330
Ensembl chrNW_004936479:9,584,221...9,610,420
JBrowse link
G Lynx1 Ly6/neurotoxin 1 enables ISO (PMID:11906696) MGI PMID:11906696 NCBI chrNW_004936470:9,109,888...9,115,271 JBrowse link
G Rack1 receptor for activated C kinase 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936826:748,256...753,460
Ensembl chrNW_004936826:747,291...753,442
JBrowse link
G Stom stomatin enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:9,808,586...9,837,506
Ensembl chrNW_004936487:9,808,194...9,837,530
JBrowse link
G Stoml1 stomatin like 1 enables ISO (PMID:24247984) MGI PMID:24247984 NCBI chrNW_004936471:33,123,662...33,133,017
Ensembl chrNW_004936471:33,124,345...33,132,931
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:17,492,718...17,508,571
Ensembl chrNW_004936490:17,492,753...17,509,582
JBrowse link
potassium channel inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 enables ISO PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chrNW_004936602:4,264,896...4,278,160
Ensembl chrNW_004936602:4,264,889...4,278,161
JBrowse link
G Ensa endosulfine alpha enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:803,452...859,215
Ensembl chrNW_004936580:851,907...859,213
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 enables ISO (PMID:27162025) UniProt PMID:27162025 NCBI chrNW_004936569:4,939,477...4,942,096
Ensembl chrNW_004936569:4,939,511...4,942,038
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 enables ISO PMID:24196565 UniProt PMID:24196565 RGD:8661627 NCBI chrNW_004936628:3,155,261...3,284,375
Ensembl chrNW_004936628:3,154,109...3,345,660
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:6,106,284...6,318,339
Ensembl chrNW_004936497:6,106,268...6,318,354
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 enables ISO
IEA
RGD
TreeGrafter
PMID:16775035 GO_REF:0000118 RGD:2298792 NCBI chrNW_004936606:933,637...1,069,885
Ensembl chrNW_004936606:934,337...1,067,275
JBrowse link
G Wnk2 WNK lysine deficient protein kinase 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936487:2,537,630...2,657,172
Ensembl chrNW_004936487:2,537,630...2,657,173
JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936751:1,095,578...1,266,772
Ensembl chrNW_004936751:1,100,192...1,266,740
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936490:17,492,718...17,508,571
Ensembl chrNW_004936490:17,492,753...17,509,582
JBrowse link
sodium channel inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2d calcium/calmodulin dependent protein kinase II delta enables ISO (PMID:22514276) BHF-UCL PMID:22514276 NCBI chrNW_004936563:4,226,412...4,526,139
Ensembl chrNW_004936563:4,227,986...4,526,118
JBrowse link
G Commd1 copper metabolism domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936491:7,247,160...7,421,039
Ensembl chrNW_004936491:7,247,140...7,420,921
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:17,254,777...17,374,725
Ensembl chrNW_004936471:17,252,234...17,374,804
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936497:6,106,284...6,318,339
Ensembl chrNW_004936497:6,106,268...6,318,354
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936522:6,271,339...6,300,202
Ensembl chrNW_004936522:6,272,507...6,299,917
JBrowse link
G Rsc1a1 regulator of solute carriers 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:3,284,512...3,312,366
Ensembl chrNW_004936474:3,307,377...3,312,066
Ensembl chrNW_004936474:3,307,377...3,312,066
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 enables IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936570:1,187,916...1,195,423
Ensembl chrNW_004936570:1,186,711...1,195,388
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936542:8,082,487...8,106,154
Ensembl chrNW_004936542:8,086,702...8,105,372
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17094
    molecular function regulator activity 1788
      transporter regulator activity 153
        channel regulator activity 151
          channel inhibitor activity 44
            ion channel inhibitor activity + 42
paths to the root