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ONTOLOGY REPORT - ANNOTATIONS


Term:melatonin receptor activity
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Accession:GO:0008502 term browser browse the term
Definition:Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.



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melatonin receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr50 G protein-coupled receptor 50 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:149,368,900...149,373,486
Ensembl chr  X:149,368,900...149,373,486
JBrowse link
G Mtnr1a melatonin receptor 1A enables ISO
IEA
(PMID:10531408)
GO_REF:0000002
RGD
InterPro
PMID:10531408 GO_REF:0000002 NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919
JBrowse link
G Mtnr1b melatonin receptor 1B enables ISO (PMID:8923472) RGD PMID:8923472 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737
JBrowse link
G Rorb RAR-related orphan receptor B enables IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:7961794 GO_REF:0000033, RGD:2314873 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390
JBrowse link

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  molecular_function 20488
    molecular transducer activity 2581
      signaling receptor activity 2581
        transmembrane signaling receptor activity 2384
          G protein-coupled receptor activity 1951
            melatonin receptor activity 4
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