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ONTOLOGY REPORT - ANNOTATIONS

Term:calcium- and calmodulin-responsive adenylate cyclase activity
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Accession:GO:0008294 term browser browse the term
Definition:Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.
Synonyms:exact_synonym: calcium- and calmodulin-responsive adenylyl cyclase activity;   calcium/calmodulin-responsive adenylate cyclase activity
 xref: reactome:R-HSA-111930 "Adenylate cyclase produces cAMP";   reactome:R-HSA-442715 "Calmodulin-activated adenylate cyclases ADCY1 and ADCY8 generate cAMP"


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calcium- and calmodulin-responsive adenylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 IDA RGD PMID:14985420 RGD:2312640 NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969 		JBrowse link
G Adcy3 adenylate cyclase 3 IDA RGD PMID:12711600 RGD:2312674 NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686 		JBrowse link
G Adcy5 adenylate cyclase 5 IDA RGD PMID:10894801 RGD:2315006 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adcy6 adenylate cyclase 6 enables IDA
ISO		 (PMID:1379717) RGD PMID:1379717 PMID:10894801 RGD:2315006 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754 		JBrowse link
G Adcy8 adenylate cyclase 8 enables IDA
IEA
ISO		 PMID:11856299
PMID:13680124
PMID:8557635
PMID:19158400
GO_REF:0000107
(MGI:1860567|PMID:10864938)		 Ensembl
RGD		 PMID:10864938 PMID:8163524 PMID:11856299 PMID:13680124 PMID:8557635 More... GO_REF:0000107 MGI:1860567, RGD:69741, RGD:13800543, RGD:2312682, RGD:13825188, RGD:13800545 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6153
      cyclase activity 24
        adenylate cyclase activity 19
          calcium- and calmodulin-responsive adenylate cyclase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6153
      lyase activity 212
        phosphorus-oxygen lyase activity 27
          adenylate cyclase activity 19
            calcium- and calmodulin-responsive adenylate cyclase activity 5
paths to the root