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ONTOLOGY REPORT - ANNOTATIONS

Term:mitotic centrosome separation
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Accession:GO:0007100 term browser browse the term
Definition:Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.


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mitotic centrosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurka aurora kinase A acts_upstream_of_or_within IGI
IMP		 (PMID:17060449)
(PMID:19075002)		 MGI PMID:17060449 PMID:19075002 NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455 		JBrowse link
G Kif11 kinesin family member 11 acts_upstream_of_or_within IMP (PMID:12840069) MGI PMID:12840069 NCBI chr19:37,364,830...37,410,311
Ensembl chr19:37,364,851...37,410,307 		JBrowse link
G Nde1 nudE neurodevelopment protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:13,981,139...14,010,792
Ensembl chr16:13,981,139...14,010,792 		JBrowse link
G Ndel1 nudE neurodevelopment protein 1 like 1 involved_in
acts_upstream_of_or_within		 IBA
IGI
IMP		 (PMID:17060449) GO_Central
MGI		 PMID:17060449 GO_REF:0000033 NCBI chr11:68,712,260...68,743,961
Ensembl chr11:68,712,260...68,762,684 		JBrowse link
G Nup62 nucleoporin 62 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:44,465,512...44,481,260
Ensembl chr 7:44,465,512...44,480,236 		JBrowse link
positive regulation of mitotic centrosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsfl1c NSFL1 (p97) cofactor (p47) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:151,336,102...151,353,230
Ensembl chr 2:151,336,102...151,353,334 		JBrowse link
G Ranbp1 RAN binding protein 1 acts_upstream_of_or_within
involved_in		 IDA
IBA		 (PMID:12840069) MGI
GO_Central		 PMID:12840069 GO_REF:0000033 NCBI chr16:18,057,843...18,066,558
Ensembl chr16:18,057,648...18,066,596 		JBrowse link
G Ubxn2b UBX domain protein 2B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:6,191,105...6,219,788
Ensembl chr 4:6,191,098...6,221,688 		JBrowse link
regulation of mitotic centrosome separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cep85 centrosomal protein 85 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:133,857,169...133,914,420
Ensembl chr 4:133,857,169...133,914,423 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361 		JBrowse link
G Kif11 kinesin family member 11 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:37,364,830...37,410,311
Ensembl chr19:37,364,851...37,410,307 		JBrowse link
G Map9 microtubule-associated protein 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:82,265,379...82,302,575
Ensembl chr 3:82,265,351...82,302,575 		JBrowse link
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:191,553,622...191,565,161
Ensembl chr 1:191,553,556...191,565,162 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    cellular process 17546
      cell cycle process 1354
        centrosome separation 13
          mitotic centrosome separation 12
            negative regulation of mitotic centrosome separation 0
            positive regulation of mitotic centrosome separation 3
            regulation of mitotic centrosome separation + 8
Path 2
Term Annotations click to browse term
  biological_process 28576
    cellular process 17546
      cellular component organization or biogenesis 6970
        cellular component organization 6747
          organelle organization 3706
            cytoskeleton organization 1526
              microtubule cytoskeleton organization 681
                microtubule organizing center organization 154
                  centrosome cycle 141
                    centrosome separation 13
                      mitotic centrosome separation 12
                        negative regulation of mitotic centrosome separation 0
                        positive regulation of mitotic centrosome separation 3
                        regulation of mitotic centrosome separation + 8
paths to the root