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ONTOLOGY REPORT - ANNOTATIONS

Term:Hrd1p ubiquitin ligase ERAD-L complex
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Accession:GO:0000839 term browser browse the term
Definition:A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.


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Hrd1p ubiquitin ligase ERAD-L complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DERL1 derlin 1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 8:119,707,397...119,736,502
Ensembl chr 8:122,463,063...122,492,137 		JBrowse link
G DERL2 derlin 2 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr17:5,519,183...5,534,145
Ensembl chr17:5,514,440...5,526,363 		JBrowse link
G DERL3 derlin 3 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr22:4,589,448...4,594,628
Ensembl chr22:22,673,908...22,678,444 		JBrowse link
G RHBDD2 rhomboid domain containing 2 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 7:68,132,256...68,142,198
Ensembl chr 7:82,328,777...82,338,401 		JBrowse link
G SEL1L SEL1L adaptor subunit of SYVN1 ubiquitin ligase part_of IEA Ensembl GO_REF:0000107 NCBI chr14:62,050,695...62,111,489
Ensembl chr14:81,248,441...81,309,597 		JBrowse link
G SYVN1 synoviolin 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr11:60,489,626...60,496,945
Ensembl chr11:63,829,138...63,834,364 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17180
    protein-containing complex 5908
      endoplasmic reticulum protein-containing complex 129
        ER ubiquitin ligase complex 7
          Hrd1p ubiquitin ligase complex 7
            Hrd1p ubiquitin ligase ERAD-L complex 6
Path 2
Term Annotations click to browse term
  cellular_component 17180
    cellular anatomical entity 16967
      organelle 12496
        intracellular organelle 12077
          intracellular membrane-bounded organelle 10862
            endoplasmic reticulum 1634
              endoplasmic reticulum subcompartment 812
                endoplasmic reticulum membrane 800
                  ER ubiquitin ligase complex 7
                    Hrd1p ubiquitin ligase complex 7
                      Hrd1p ubiquitin ligase ERAD-L complex 6
paths to the root