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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of ubiquitin-dependent protein catabolic process
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Accession:GO:2000059 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process.
Synonyms:narrow_synonym: negative regulation of protein ubiquitination during ubiquitin-dependent protein breakdown;   negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolism;   negative regulation of protein ubiquitination during ubiquitin-dependent protein degradation;   negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;   negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process;   negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism;   negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process;   negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism
 related_synonym: negative regulation of protein degradation tagging activity;   negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process


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negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (PMID:20100865) MGI PMID:20100865 NCBI chr 7:30,812,925...30,995,369
Ensembl chr 7:30,812,920...30,995,360 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:16173922), (PMID:18560357)
(PMID:23277542)		 UniProt
MGI		 PMID:16173922 PMID:18560357 PMID:23277542 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:19,975,030...20,016,768
Ensembl chr 6:19,976,930...20,016,923 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:9,940,535...10,141,815
Ensembl chr18:9,861,792...10,135,065 		JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23792958) MGI
Ensembl		 PMID:23792958 GO_REF:0000107 NCBI chr 3:53,681,798...53,693,034
Ensembl chr 3:53,674,509...53,692,928 		JBrowse link
G PML PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:112,698,865...112,710,305
Ensembl chr 4:112,701,088...112,703,581 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251 		JBrowse link
G QRICH2 glutamine rich 2 involved_in ISO (PMID:30683861)
(MGI:6277293|PMID:30683861)		 UniProt PMID:30683861 MGI:6277293 NCBI chr12:5,174,531...5,203,797
Ensembl chr12:5,176,926...5,199,272 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 6:81,523,510...81,526,925
Ensembl chr 6:81,522,742...81,530,436 		JBrowse link
G RPL23 ribosomal protein L23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,279,965...23,285,538
Ensembl chr12:23,279,965...23,285,515 		JBrowse link
G RPL5 ribosomal protein L5 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 4:124,359,786...124,367,612
Ensembl chr 4:124,358,594...124,367,645 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:131,258,709...131,263,285
Ensembl chr 3:131,258,722...131,263,256 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:75,879,081...75,896,279
Ensembl chr 2:75,879,058...75,896,277 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,626,003 		JBrowse link
G SVIP small VCP interacting protein involved_in ISO PMID:17000876 ParkinsonsUK-UCL PMID:17000876 RGD:10047192 NCBI chr 2:36,703,757...36,714,018
Ensembl chr 2:36,703,790...36,714,934 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chr  X:57,382,211...57,466,700
Ensembl chr  X:57,382,354...57,466,697 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,047,048...23,062,974
Ensembl chr 7:23,047,520...23,062,487 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:106,087,921...106,139,717
Ensembl chr 6:106,087,924...106,139,379 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,843,742...63,858,835
Ensembl chr 5:63,843,745...63,858,716 		JBrowse link
G WNT1 Wnt family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16601693) Ensembl
MGI		 PMID:16601693 GO_REF:0000107 NCBI chr 5:15,010,607...15,015,007
Ensembl chr 5:15,010,786...15,014,998 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IEA Ensembl GO_REF:0000107
G BAG6 BAG cochaperone 6 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,756,897...23,768,659
Ensembl chr 7:23,756,899...23,775,892 		JBrowse link
G CAMLG calcium modulating ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:136,957,626...136,967,944
Ensembl chr 2:136,957,508...136,968,382 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:6,860,052...6,874,334
Ensembl chr14:6,859,664...6,874,327 		JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,320 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr17:34,692,960...34,748,067 JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr 6:19,975,030...20,016,768
Ensembl chr 6:19,976,930...20,016,923 		JBrowse link
G CSNK2B casein kinase 2 beta involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr 7:23,781,194...23,787,914
Ensembl chr 7:23,780,362...23,788,678
Ensembl chr 7:23,780,362...23,788,678 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,977...32,491,396 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:21,955,026...22,053,683
Ensembl chr 4:21,954,874...22,058,699 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:41,443,963...42,884,799
Ensembl chr13:41,443,965...42,392,817 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,780,447...64,794,922
Ensembl chr 2:64,780,442...64,794,919 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:39,237,299...39,250,479
Ensembl chr 7:39,244,458...39,250,481 		JBrowse link
G KHNYN KH and NYN domain containing involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:74,854,209...74,872,491
Ensembl chr 7:74,854,379...74,874,882 		JBrowse link
G KLHL40 kelch like family member 40 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:24960163) GO_Central
MGI		 PMID:24960163 GO_REF:0000033 NCBI chr13:26,202,607...26,211,528
Ensembl chr13:26,202,677...26,211,522 		JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISO (MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:5703671 NCBI chr 1:127,916,639...127,936,952
Ensembl chr 1:127,916,644...127,936,955 		JBrowse link
G MTM1 myotubularin 1 acts_upstream_of_or_within ISO (PMID:23695157) MGI PMID:23695157 NCBI chr  X:122,286,904...122,379,302
Ensembl chr  X:122,286,916...122,379,299 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:36,122,189...36,177,965
Ensembl chr 6:36,122,035...36,174,504 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,443,453...53,451,707
Ensembl chr 6:53,443,385...53,452,017 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:57,521,091...57,558,467
Ensembl chr  X:57,521,098...57,558,515 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,516 		JBrowse link
G PBK PDZ binding kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21715333) Ensembl
MGI		 PMID:21715333 GO_REF:0000107 NCBI chr14:11,543,657...11,577,286
Ensembl chr14:11,543,603...11,566,702 		JBrowse link
G PHF20L1 PHD finger protein 20 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:8,394,874...8,468,309
Ensembl chr 4:8,394,897...8,468,297 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:81,523,510...81,526,925
Ensembl chr 6:81,522,742...81,530,436 		JBrowse link
G RYBP RING1 and YY1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:53,724,062...53,809,698
Ensembl chr13:53,724,065...53,809,601 		JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO (PMID:17981124) MGI PMID:17981124 NCBI chr 5:78,419,849...78,476,315
Ensembl chr 5:78,423,383...78,476,195 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16611981) Ensembl
MGI		 PMID:16611981 GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22285184) Ensembl
MGI		 PMID:22285184 GO_REF:0000107 NCBI chr13:30,409,979...30,576,270
Ensembl chr13:30,409,983...30,601,441 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,494,841...47,499,568
Ensembl chr16:47,490,027...47,495,880 		JBrowse link
G TLK2 tousled like kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:16,129,249...16,256,642
Ensembl chr12:16,129,256...16,256,359 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:23,047,048...23,062,974
Ensembl chr 7:23,047,520...23,062,487 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO (PMID:31537781) MGI PMID:31537781 NCBI chr 9:45,829,014...45,838,978
Ensembl chr 9:45,829,191...45,838,979 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:9,072,549...9,075,595
Ensembl chr 2:9,072,968...9,075,594 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:725,688...761,633
Ensembl chr10:725,561...763,985 		JBrowse link
G USP26 ubiquitin specific peptidase 26 involved_in ISO (PMID:28839133)
(MGI:5926846|PMID:28839133)		 UniProt PMID:28839133 MGI:5926846 NCBI chr  X:109,092,622...109,095,548 JBrowse link
G USP38 ubiquitin specific peptidase 38 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:84,567,476...84,601,044
Ensembl chr 8:84,567,618...84,601,224 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:33,754,357...33,810,480
Ensembl chr 3:33,775,829...33,810,465 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:36,736,049...36,888,702
Ensembl chr  X:36,760,865...36,885,250 		JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:39,932,562...40,024,114
Ensembl chr10:39,932,599...40,022,338 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PABPN1L PABPN1 like, cytoplasmic acts_upstream_of_or_within ISO (PMID:32558204) MGI PMID:32558204 NCBI chr 6:854,605...861,969
Ensembl chr 6:858,888...861,604 		JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:182,357,597...182,407,792
Ensembl chr 1:182,357,607...182,407,782 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17805
    metabolic process 10374
      negative regulation of metabolic process 3049
        negative regulation of catabolic process 366
          negative regulation of ubiquitin-dependent protein catabolic process 61
            negative regulation of proteasomal ubiquitin-dependent protein catabolic process + 42
Path 2
Term Annotations click to browse term
  biological_process 17805
    biological regulation 12904
      regulation of biological process 12537
        regulation of metabolic process 6219
          regulation of macromolecule metabolic process 5690
            regulation of protein metabolic process 1831
              regulation of proteolysis 405
                negative regulation of proteolysis 145
                  negative regulation of proteolysis involved in protein catabolic process 77
                    negative regulation of ubiquitin-dependent protein catabolic process 61
                      negative regulation of proteasomal ubiquitin-dependent protein catabolic process + 42
paths to the root