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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of autophagy of mitochondrion
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Accession:GO:1903599 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy.
Comment:An example of this AMBRA1 - human (Q9C0C7) in PMID:21753002 inferred from direct assay
Synonyms:exact_synonym: up regulation of mitochondrion degradation;   up regulation of mitophagy;   upregulation of mitochondrion degradation;   upregulation of mitophagy
 narrow_synonym: activation of mitophagy
 broad_synonym: positive regulation of mitochondrial degradation
 related_synonym: activation of mitochondrion degradation


show annotations for term's descendants           Sort by:
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2/adenovirus E1B interacting protein 3 involved_in ISO RGD
MGI		 PMID:23698117 GO_REF:0000096 MGI:4417868 RGD:11561968 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Fbxo7 F-box protein 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy/beclin 1 regulator 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:91,560,464...91,749,194
Ensembl chr 2:91,560,479...91,749,194 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:70,768,425...70,784,238
Ensembl chr 8:70,768,425...70,784,242 		JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO (PMID:38340717) UniProt PMID:38340717 NCBI chr18:38,383,302...38,395,682
Ensembl chr18:38,383,308...38,398,514 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISO (PMID:38340717) UniProt PMID:38340717 NCBI chr 5:143,803,586...143,839,535
Ensembl chr 5:143,803,543...143,841,069 		JBrowse link
G Fbxo7 F-box protein 7 involved_in ISO MGI GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit involved_in IMP (MGI:3796473|PMID:18281291) ParkinsonsUK-UCL PMID:18281291 MGI:3796473 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Htt huntingtin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878 		JBrowse link
G Igtp interferon gamma induced GTPase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417 		JBrowse link
G Irgm1 immunity-related GTPase family M member 1 involved_in IMP
ISO		 (MGI:6705154|PMID:33510463) UniProt
MGI		 PMID:33510463 GO_REF:0000119 MGI:4834177 MGI:6705154 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510 		JBrowse link
G Irgm2 immunity-related GTPase family M member 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in IMP (MGI:6388731|PMID:31919280) UniProt PMID:31919280 MGI:6388731 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO RGD
MGI		 PMID:28608965 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:13432560 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 involved_in IDA (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321 		JBrowse link
G Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 involved_in IDA (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr  X:36,059,250...36,062,461
Ensembl chr  X:36,059,304...36,062,460 		JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 involved_in ISO PMID:29934347 UniProt PMID:29934347 RGD:405650300 NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378 		JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A involved_in ISO (PMID:23685073) UniProt PMID:23685073 NCBI chr  X:36,137,948...36,147,875
Ensembl chr  X:36,064,828...36,147,875 		JBrowse link
G Vps13d vacuolar protein sorting 13D involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:144,597,619...144,921,598
Ensembl chr 4:144,699,192...144,921,575 		JBrowse link
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vdac1 voltage-dependent anion channel 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    cellular process 17548
      process utilizing autophagic mechanism 556
        autophagy 556
          autophagy of mitochondrion 111
            positive regulation of autophagy of mitochondrion 19
              positive regulation of mitophagy + 18
Path 2
Term Annotations click to browse term
  biological_process 28576
    biological regulation 13125
      regulation of biological process 12730
        regulation of metabolic process 6599
          regulation of catabolic process 1143
            regulation of cellular catabolic process 438
              regulation of autophagy 324
                positive regulation of autophagy 169
                  positive regulation of autophagy of mitochondrion 19
                    positive regulation of mitophagy + 18
paths to the root