Prkn (parkin RBR E3 ubiquitin protein ligase) - Rat Genome Database

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Gene: Prkn (parkin RBR E3 ubiquitin protein ligase) Mus musculus
Analyze
Symbol: Prkn
Name: parkin RBR E3 ubiquitin protein ligase
RGD ID: 62089
MGI Page MGI
Description: Enables ubiquitin protein ligase activity. Involved in several processes, including negative regulation of intrinsic apoptotic signaling pathway; positive regulation of dendrite extension; and positive regulation of protein linear polyubiquitination. Acts upstream of or within several processes, including catecholamine metabolic process; chemical synaptic transmission; and mitophagy. Located in mitochondrion; neuron projection; and nucleus. Part of protein-containing complex. Is active in dopaminergic synapse. Is expressed in several structures, including face; nervous system; pancreas; sensory organ; and skeleton. Used to study Parkinson's disease 2. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinson's disease 2; lung cancer; and ovarian cancer. Orthologous to human PRKN (parkin RBR E3 ubiquitin protein ligase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase parkin; MGC130518; P; Pa; Park2; parkin protein; parkin RBR E3 ubiquitin-protein ligase; Parkinson disease (autosomal recessive, juvenile) 2, parkin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391711,059,227 - 12,282,257 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1711,059,271 - 12,282,248 (+)EnsemblGRCm39 Ensembl
GRCm381710,840,359 - 12,063,370 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1710,840,384 - 12,063,361 (+)EnsemblGRCm38mm10GRCm38
MGSCv371711,033,250 - 12,256,227 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361710,683,742 - 11,906,719 (+)NCBIMGSCv36mm8
Celera1710,880,667 - 12,092,859 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map177.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-selegiline  (ISO)
(1->4)-beta-D-glucan  (EXP)
(R)-lipoic acid  (EXP)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
1,3-dichloropropan-2-ol  (ISO)
1,4-benzoquinone  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3-BROMO-7-NITROINDAZOLE  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (ISO)
4-hydroxy-TEMPO  (ISO)
6-propyl-2-thiouracil  (ISO)
acetaldehyde  (ISO)
acetamide  (ISO)
acetylcholine  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
aluminium atom  (EXP)
aluminium(0)  (EXP)
ammonium chloride  (ISO)
amphetamine  (EXP)
androgen antagonist  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bupivacaine  (EXP)
Butylparaben  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cantharidin  (EXP)
carbon nanotube  (EXP)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (EXP)
carnosic acid  (ISO)
CCCP  (EXP,ISO)
CGP 52608  (ISO)
chloroquine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (EXP,ISO)
cinnarizine  (EXP)
cisplatin  (ISO)
clothianidin  (ISO)
coenzyme Q10  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
DDE  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (ISO)
dioxygen  (EXP,ISO)
dopamine  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
emtricitabine  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
epoxomicin  (ISO)
ethanol  (EXP,ISO)
fenpyroximate  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
furan  (ISO)
furosemide  (ISO)
Genipin  (EXP)
glucose  (ISO)
glutathione  (EXP)
Honokiol  (ISO)
hydrogen peroxide  (EXP,ISO)
indole-3-methanol  (ISO)
indometacin  (EXP)
inositol  (ISO)
iodixanol  (ISO)
ketoconazole  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
linsidomine  (ISO)
linuron  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (ISO)
luteolin  (EXP)
lycopene  (EXP)
maneb  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melatonin  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (EXP)
miconazole  (ISO)
minocycline  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (EXP)
nickel dichloride  (EXP)
nicotine  (ISO)
O-acetyl-L-carnitine  (EXP)
O-methyleugenol  (ISO)
oligomycin A  (ISO)
oxidopamine  (EXP,ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
picoxystrobin  (ISO)
poly(vinylpyrrolidone)  (EXP)
prochloraz  (ISO)
procymidone  (ISO)
pyrimidifen  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rimonabant  (EXP,ISO)
rotenone  (EXP,ISO)
rutin  (ISO)
S-nitrosoglutathione  (ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
sirolimus  (EXP,ISO)
sirtinol  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
sorafenib  (EXP,ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
taurine  (ISO)
tebufenpyrad  (ISO)
tenofovir disoproxil fumarate  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
Tiron  (EXP,ISO)
titanium dioxide  (ISO)
trans-piceid  (ISO)
trifloxystrobin  (ISO)
trifluoperazine  (ISO)
trimellitic anhydride  (EXP)
tubocurarine  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult locomotory behavior  (IMP)
aggresome assembly  (ISO)
autophagy  (IEA)
cellular response to hydrogen sulfide  (ISO)
cellular response to L-glutamate  (ISO)
cellular response to L-glutamine  (ISO)
cellular response to manganese ion  (ISO)
cellular response to oxidative stress  (ISO)
cellular response to toxic substance  (IDA,ISO)
dopamine metabolic process  (IMP)
dopamine uptake involved in synaptic transmission  (IMP)
free ubiquitin chain polymerization  (ISO)
learning  (IMP)
locomotory behavior  (IMP)
mitochondrial fragmentation involved in apoptotic process  (ISO)
mitochondrion localization  (ISO)
mitochondrion to lysosome vesicle-mediated transport  (ISO)
mitophagy  (IGI,ISO)
modulation of chemical synaptic transmission  (IMP)
negative regulation by host of viral genome replication  (ISO)
negative regulation of actin filament bundle assembly  (ISO)
negative regulation of canonical Wnt signaling pathway  (ISO)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  (IMP,ISO)
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway  (IGI,IMP)
negative regulation of excitatory postsynaptic potential  (ISO)
negative regulation of exosomal secretion  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of insulin secretion  (ISO)
negative regulation of intralumenal vesicle formation  (ISO)
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator  (ISO)
negative regulation of mitochondrial fission  (ISO)
negative regulation of neuron apoptotic process  (IMP,ISO)
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway  (IMP,ISO)
negative regulation of protein phosphorylation  (IBA,ISO)
negative regulation of reactive oxygen species biosynthetic process  (ISO)
negative regulation of reactive oxygen species metabolic process  (ISO)
negative regulation of release of cytochrome c from mitochondria  (ISO)
negative regulation of spontaneous neurotransmitter secretion  (ISO)
negative regulation of synaptic transmission, glutamatergic  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
norepinephrine metabolic process  (IMP)
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of ATP biosynthetic process  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (ISO)
positive regulation of dendrite extension  (IGI)
positive regulation of gene expression  (ISO)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
positive regulation of mitochondrial fusion  (ISO)
positive regulation of mitochondrial membrane potential  (ISO)
positive regulation of mitophagy  (ISO)
positive regulation of mitophagy in response to mitochondrial depolarization  (ISO)
positive regulation of neurotransmitter uptake  (ISO)
positive regulation of proteasomal protein catabolic process  (ISO)
positive regulation of protein linear polyubiquitination  (IMP,ISO)
positive regulation of protein localization to membrane  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of tumor necrosis factor-mediated signaling pathway  (ISO)
proteasomal protein catabolic process  (ISO)
proteasome-mediated ubiquitin-dependent protein catabolic process  (ISO)
protein autoubiquitination  (ISO)
protein catabolic process  (IMP)
protein destabilization  (IMP,ISO)
protein K11-linked ubiquitination  (ISO)
protein K48-linked ubiquitination  (ISO)
protein K6-linked ubiquitination  (ISO)
protein K63-linked ubiquitination  (ISO)
protein localization to mitochondrion  (IMP,ISO)
protein monoubiquitination  (ISO)
protein polyubiquitination  (IBA,ISO)
protein stabilization  (ISO)
protein ubiquitination  (ISO)
regulation of apoptotic process  (IBA)
regulation of autophagy  (ISO)
regulation of cellular response to oxidative stress  (IBA,ISO)
regulation of dopamine metabolic process  (ISO)
regulation of mitochondrial membrane potential  (IGI)
regulation of mitochondrion organization  (IBA,ISO)
regulation of neurotransmitter secretion  (IMP)
regulation of postsynaptic membrane neurotransmitter receptor levels  (ISO)
regulation of protein stability  (ISO)
regulation of protein ubiquitination  (ISO)
regulation of reactive oxygen species metabolic process  (ISO)
regulation of synaptic vesicle endocytosis  (IDA,IEP,IMP)
regulation protein catabolic process at presynapse  (IDA,IEP,IMP)
response to corticosterone  (ISO)
response to curcumin  (ISO)
response to endoplasmic reticulum stress  (IMP,ISO)
response to muscle activity  (ISO)
response to unfolded protein  (ISO)
response to xenobiotic stimulus  (ISO)
startle response  (IMP)
synaptic transmission, dopaminergic  (IMP)
synaptic transmission, glutamatergic  (IMP)
ubiquitin-dependent protein catabolic process  (IBA,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal autophagy  (IAGP)
abnormal axonal transport  (IAGP)
abnormal cellular respiration  (IAGP)
abnormal CNS glial cell morphology  (IAGP)
abnormal dopamine level  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal locus ceruleus morphology  (IAGP)
abnormal mitochondrial ATP synthesis coupled electron transport  (IAGP)
abnormal mitochondrial morphology  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal mitophagy  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal posture  (IAGP)
abnormal redox activity  (IAGP)
abnormal respiratory function  (IAGP)
abnormal response to cardiac infarction  (IAGP)
abnormal spatial learning  (IAGP)
abnormal stationary movement  (IAGP)
abnormal substantia nigra pars compacta morphology  (IAGP)
abnormal synaptic transmission  (IAGP)
abnormal tail movements  (IAGP)
alopecia  (IAGP)
brain vacuoles  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased core body temperature  (IAGP)
decreased dopamine level  (IAGP)
decreased dopaminergic neuron number  (IAGP)
decreased exploration in new environment  (IAGP)
decreased mitochondrial size  (IAGP)
decreased noradrenaline level  (IAGP)
decreased startle reflex  (IAGP)
decreased substantia nigra size  (IAGP)
hippocampal neuron degeneration  (IAGP)
impaired behavioral response to xenobiotic  (IAGP)
impaired coordination  (IAGP)
increased anxiety-related response  (IAGP)
increased dopamine level  (IAGP)
increased neuron apoptosis  (IAGP)
increased sensitivity to induced cell death  (IAGP)
increased serotonin level  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased thigmotaxis  (IAGP)
kyphosis  (IAGP)
loss of dopaminergic neurons  (IAGP)
neuron degeneration  (IAGP)
neuronal cytoplasmic inclusions  (IAGP)
oxidative stress  (IAGP)
premature death  (IAGP)
short stride length  (IAGP)
tau protein deposits  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Genes associated with Parkinson's disease: regulation of autophagy and beyond. Beilina A and Cookson MR, J Neurochem. 2015 Jul 30. doi: 10.1111/jnc.13266.
2. Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats. Candeias E, etal., Mol Neurobiol. 2017 Jun 2. doi: 10.1007/s12035-017-0622-3.
3. Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation. Cao S, etal., Sci Rep. 2017 May 25;7(1):2417. doi: 10.1038/s41598-017-02679-z.
4. The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. Ciechanover A and Brundin P, Neuron 2003 Oct 9;40(2):427-46.
5. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Durcan TM and Fon EA, Genes Dev. 2015 May 15;29(10):989-99. doi: 10.1101/gad.262758.115.
6. Thymoquinone exerts neuroprotective effect in animal model of Parkinson's disease. Ebrahimi SS, etal., Toxicol Lett. 2017 Jul 5;276:108-114. doi: 10.1016/j.toxlet.2017.05.018. Epub 2017 May 17.
7. Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease. Foroud T, etal., Neurology 2003 Mar 11;60(5):796-801.
8. Cloning of rat parkin cDNA and distribution of parkin in rat brain. Gu WJ, etal., J Neurochem 2000 Apr;74(4):1773-6.
9. Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress. Han K, etal., Sci Rep. 2017 May 18;7(1):2093. doi: 10.1038/s41598-017-02339-2.
10. Parkin overexpression ameliorates hippocampal long-term potentiation and beta-amyloid load in an Alzheimer's disease mouse model. Hong X, etal., Hum Mol Genet. 2014 Feb 15;23(4):1056-72. doi: 10.1093/hmg/ddt501. Epub 2013 Oct 8.
11. Parkin and synphilin-1 isoform expression changes in Lewy body diseases. Humbert J, etal., Neurobiol Dis. 2007 Jun;26(3):681-7. Epub 2007 Mar 27.
12. Impaired intracellular trafficking defines early Parkinson's disease. Hunn BH, etal., Trends Neurosci. 2015 Mar;38(3):178-88. doi: 10.1016/j.tins.2014.12.009. Epub 2015 Jan 29.
13. Melatonin enhances mitophagy and mitochondrial biogenesis in rats with carbon tetrachloride-induced liver fibrosis. Kang JW, etal., J Pineal Res. 2016 May;60(4):383-93. doi: 10.1111/jpi.12319. Epub 2016 Mar 7.
14. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
15. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Kitada T, etal., Nature. 1998 Apr 9;392(6676):605-8.
16. Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function. Ko HS, etal., Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16691-6. doi: 10.1073/pnas.1006083107. Epub 2010 Sep 7.
17. Mitochondria and mitophagy: the yin and yang of cell death control. Kubli DA and Gustafsson AB, Circ Res. 2012 Oct 12;111(9):1208-21. doi: 10.1161/CIRCRESAHA.112.265819.
18. Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease? Mengesdorf T, etal., Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15042-7. Epub 2002 Nov 1.
19. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
20. MGDs mouse GO annotations MGD data from the GO Consortium
21. MGD IEA MGD IEA
22. Genetic and epigenetic alterations affecting PARK-2 expression in cervical neoplasm among North Indian patients. Naseem A, etal., Tumour Biol. 2017 Jun;39(6):1010428317703635. doi: 10.1177/1010428317703635.
23. Motor alterations are reduced in mice lacking the PARK2 gene in the presence of a human FTDP-17 mutant form of four-repeat tau. Navarro P, etal., J Neurol Sci. 2008 Dec 15;275(1-2):139-44. doi: 10.1016/j.jns.2008.08.013. Epub 2008 Sep 24.
24. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
25. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
26. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
27. Mouse MP Annotation Import Pipeline RGD automated import pipeline
28. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
29. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
30. Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson's disease. Rosa AI, etal., Biochim Biophys Acta. 2017 Sep;1863(9):2171-2181. doi: 10.1016/j.bbadis.2017.06.004. Epub 2017 Jun 3.
31. Effects of partial suppression of parkin on huntingtin mutant R6/1 mice. Rubio I, etal., Brain Res. 2009 Jul 24;1281:91-100. doi: 10.1016/j.brainres.2009.05.039. Epub 2009 May 21.
32. Parkin and PINK1: much more than mitophagy. Scarffe LA, etal., Trends Neurosci. 2014 Jun;37(6):315-24. doi: 10.1016/j.tins.2014.03.004. Epub 2014 Apr 13.
33. Mitochondrial quality control in alveolar epithelial cells damaged by S. aureus pneumonia in mice. Suliman HB, etal., Am J Physiol Lung Cell Mol Physiol. 2017 Jun 29:ajplung.00197.2017. doi: 10.1152/ajplung.00197.2017.
34. Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease. Vercammen L, etal., Mol Ther. 2006 Nov;14(5):716-23. Epub 2006 Aug 17.
35. Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses. Wei H, etal., Biochim Biophys Acta. 2015 Oct;1853(10 Pt B):2784-90. doi: 10.1016/j.bbamcr.2015.03.013. Epub 2015 Apr 1.
36. Parkinson's disease-associated parkin colocalizes with Alzheimer's disease and multiple sclerosis brain lesions. Witte ME, etal., Neurobiol Dis. 2009 Dec;36(3):445-52. doi: 10.1016/j.nbd.2009.08.009. Epub 2009 Aug 27.
37. High expression of Parkin predicts easier recurrence of patients with adjuvant transarterial chemoembolization. Zhang C, etal., Biomark Med. 2017 Sep 1. doi: 10.2217/bmm-2017-0129.
38. Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain. Zhang CW, etal., Neuromolecular Med. 2017 Jul 10. doi: 10.1007/s12017-017-8451-0.
39. Calcium/calmodulin-dependent protein kinase regulates the PINK1/Parkin and DJ-1 pathways of mitophagy during sepsis. Zhang X, etal., FASEB J. 2017 Jun 14. pii: fj.201601096RRR. doi: 10.1096/fj.201601096RRR.
40. TDP-43 upregulation mediated by the NLRP3 inflammasome induces cognitive impairment in 2 2',4,4'-tetrabromodiphenyl ether (BDE-47)-treated mice. Zhuang J, etal., Brain Behav Immun. 2017 Oct;65:99-110. doi: 10.1016/j.bbi.2017.05.014. Epub 2017 May 19.
Additional References at PubMed
PMID:10349636   PMID:10818204   PMID:11042159   PMID:11076861   PMID:11122330   PMID:11675120   PMID:11978985   PMID:12477932   PMID:12495618   PMID:12628165   PMID:12652124   PMID:12676955  
PMID:12915482   PMID:12930822   PMID:12972409   PMID:14532270   PMID:14681479   PMID:14743368   PMID:14985362   PMID:15014970   PMID:15063093   PMID:15102676   PMID:15105460   PMID:15249681  
PMID:15252205   PMID:15684050   PMID:15882845   PMID:16092945   PMID:16096643   PMID:16135753   PMID:16141072   PMID:16141073   PMID:16150055   PMID:16332688   PMID:16375772   PMID:16455660  
PMID:16517603   PMID:16573651   PMID:16597723   PMID:16602821   PMID:16698879   PMID:16862145   PMID:16941649   PMID:17116640   PMID:17336077   PMID:17412759   PMID:17465879   PMID:17553932  
PMID:17623040   PMID:17883413   PMID:17953485   PMID:18190519   PMID:18199761   PMID:18295750   PMID:18346797   PMID:18362144   PMID:18485927   PMID:18574468   PMID:18612813   PMID:18640988  
PMID:18643794   PMID:18671761   PMID:18691389   PMID:18799693   PMID:18945890   PMID:19057915   PMID:19071114   PMID:19084014   PMID:19167501   PMID:19229105   PMID:19285961   PMID:19457102  
PMID:19546216   PMID:19591802   PMID:19617636   PMID:19631192   PMID:19680561   PMID:19815012   PMID:19909785   PMID:20064468   PMID:20089134   PMID:20089136   PMID:20232175   PMID:20404107  
PMID:20546895   PMID:20573959   PMID:20604804   PMID:20620130   PMID:20696900   PMID:20810900   PMID:20889974   PMID:20940148   PMID:20971077   PMID:21113145   PMID:21176923   PMID:21209200  
PMID:21212098   PMID:21267068   PMID:21296869   PMID:21376232   PMID:21378096   PMID:21454557   PMID:21687634   PMID:21753002   PMID:21768369   PMID:21839811   PMID:21858193   PMID:21865652  
PMID:21873635   PMID:21890690   PMID:21930938   PMID:22008525   PMID:22028146   PMID:22081612   PMID:22082830   PMID:22204976   PMID:22215441   PMID:22238104   PMID:22275429   PMID:22314364  
PMID:22342752   PMID:22342763   PMID:22460798   PMID:22564413   PMID:22792159   PMID:22872702   PMID:22954895   PMID:22960314   PMID:23095748   PMID:23152496   PMID:23256036   PMID:23258539  
PMID:23307929   PMID:23341467   PMID:23359614   PMID:23447676   PMID:23449626   PMID:23453807   PMID:23588969   PMID:23608757   PMID:23620051   PMID:23643664   PMID:23737459   PMID:23751051  
PMID:23754282   PMID:23858059   PMID:23917356   PMID:23938054   PMID:23985028   PMID:24005326   PMID:24075852   PMID:24090483   PMID:24121678   PMID:24187134   PMID:24192137   PMID:24204848  
PMID:24337465   PMID:24379352   PMID:24386307   PMID:24386432   PMID:24451648   PMID:24516131   PMID:24733019   PMID:24847002   PMID:24879156   PMID:24898855   PMID:24949970   PMID:24952961  
PMID:24959870   PMID:25083992   PMID:25154397   PMID:25216678   PMID:25244949   PMID:25316086   PMID:25348719   PMID:25349190   PMID:25403879   PMID:25447324   PMID:25471590   PMID:25486126  
PMID:25583483   PMID:25609609   PMID:25612572   PMID:25654552   PMID:25715097   PMID:25716315   PMID:25752611   PMID:25779963   PMID:25790475   PMID:25822020   PMID:25843045   PMID:26024391  
PMID:26038571   PMID:26099628   PMID:26110811   PMID:26159696   PMID:26161534   PMID:26182419   PMID:26324925   PMID:26387737   PMID:26538564   PMID:26546471   PMID:26563499   PMID:26627850  
PMID:26746235   PMID:26746706   PMID:26785495   PMID:26876175   PMID:26921108   PMID:26992930   PMID:27166280   PMID:27181353   PMID:27206984   PMID:27267045   PMID:27279371   PMID:27345367  
PMID:27430567   PMID:27597885   PMID:27689697   PMID:27693468   PMID:27754761   PMID:27794418   PMID:27852436   PMID:28042097   PMID:28063983   PMID:28086194   PMID:28103118   PMID:28254618  
PMID:28336262   PMID:28395174   PMID:28396396   PMID:28472658   PMID:28696827   PMID:28820284   PMID:28890682   PMID:28938432   PMID:28976966   PMID:29020610   PMID:29036556   PMID:29040870  
PMID:29089374   PMID:29172924   PMID:29311685   PMID:29501495   PMID:29561660   PMID:29624777   PMID:29665074   PMID:29674007   PMID:29682760   PMID:29692364   PMID:29700116   PMID:29760428  
PMID:29812989   PMID:29893854   PMID:29899409   PMID:29903906   PMID:29955050   PMID:29981809   PMID:29987020   PMID:30003648   PMID:30017357   PMID:30063115   PMID:30074231   PMID:30100261  
PMID:30126943   PMID:30135585   PMID:30244249   PMID:30290714   PMID:30329047   PMID:30378174   PMID:30385753   PMID:30404819   PMID:30411223   PMID:30449314   PMID:30763678   PMID:30786833  
PMID:30867164   PMID:30877201   PMID:30908580   PMID:30963113   PMID:30990467   PMID:31068772   PMID:31089807   PMID:31112565   PMID:31229841   PMID:31292300   PMID:31316206   PMID:31339428  
PMID:31358971   PMID:31365836   PMID:31406131   PMID:31409786   PMID:31456416   PMID:31487745   PMID:31505254   PMID:31577952   PMID:31619520   PMID:31639106   PMID:31645120   PMID:31724300  
PMID:31727366   PMID:31754185   PMID:31818196   PMID:31825802   PMID:31846738   PMID:31882005   PMID:31889458   PMID:31908016   PMID:31923460   PMID:32047033   PMID:32054064   PMID:32080200  
PMID:32275973   PMID:32291905   PMID:32325033   PMID:32364493   PMID:32427312   PMID:32427925   PMID:32444656   PMID:32457148   PMID:32499407   PMID:32545383   PMID:32597196   PMID:32627655  
PMID:32653576   PMID:32718208   PMID:32824240   PMID:32936696   PMID:32976921   PMID:33020660   PMID:33037272   PMID:33126429   PMID:33137712   PMID:33155636   PMID:33164878   PMID:33218272  
PMID:33571581   PMID:33636335   PMID:33851544   PMID:34117280   PMID:34321320   PMID:34450375   PMID:34614419   PMID:34655600   PMID:34815803   PMID:35129770   PMID:35312153   PMID:35593053  
PMID:35626675   PMID:35646911   PMID:35654037   PMID:36017378   PMID:36051438   PMID:36113482   PMID:36179903   PMID:36280265   PMID:36333379   PMID:36358952   PMID:36379251   PMID:36436456  
PMID:36519761   PMID:36593241   PMID:36608143   PMID:36656174   PMID:36658227   PMID:36691076   PMID:36750550   PMID:36754021   PMID:36758801   PMID:37029500   PMID:37165006   PMID:37259617  
PMID:37278995   PMID:37376822   PMID:37452120   PMID:37574181   PMID:37712850   PMID:37717824   PMID:37860954   PMID:37914970  


Genomics

Comparative Map Data
Prkn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391711,059,227 - 12,282,257 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1711,059,271 - 12,282,248 (+)EnsemblGRCm39 Ensembl
GRCm381710,840,359 - 12,063,370 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1710,840,384 - 12,063,361 (+)EnsemblGRCm38mm10GRCm38
MGSCv371711,033,250 - 12,256,227 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361710,683,742 - 11,906,719 (+)NCBIMGSCv36mm8
Celera1710,880,667 - 12,092,859 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map177.8NCBI
PRKN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386161,347,417 - 162,727,766 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6161,347,417 - 162,727,775 (-)EnsemblGRCh38hg38GRCh38
GRCh376161,768,449 - 163,148,798 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366161,689,661 - 163,068,793 (-)NCBINCBI36Build 36hg18NCBI36
Build 346161,740,081 - 163,119,211NCBI
Celera6162,497,923 - 163,878,436 (-)NCBICelera
Cytogenetic Map6q26NCBI
HuRef6159,224,034 - 160,600,983 (-)NCBIHuRef
CHM1_16162,031,091 - 163,411,071 (-)NCBICHM1_1
T2T-CHM13v2.06162,705,911 - 164,090,895 (-)NCBIT2T-CHM13v2.0
Prkn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8151,236,410 - 52,430,242 (-)NCBIGRCr8
mRatBN7.2148,688,651 - 49,882,520 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl148,690,556 - 49,882,555 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx149,387,875 - 50,601,445 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0155,372,640 - 56,585,891 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0149,463,372 - 50,676,968 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,880,015 - 50,069,998 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0149,684,308 - 50,875,397 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4143,151,265 - 44,374,470 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1143,154,209 - 44,377,415 (-)NCBI
Celera144,478,407 - 45,666,902 (-)NCBICelera
Cytogenetic Map1q11NCBI
Prkn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543918,664,379 - 19,951,152 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543918,664,230 - 19,953,358 (+)NCBIChiLan1.0ChiLan1.0
PRKN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25181,523,208 - 182,914,092 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16179,428,720 - 180,815,536 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06159,293,016 - 160,679,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16164,498,420 - 165,678,904 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6164,314,990 - 165,678,770 (-)Ensemblpanpan1.1panPan2
PRKN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,886,887 - 51,201,930 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl149,889,005 - 51,201,764 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha150,729,328 - 52,042,064 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0150,071,882 - 51,381,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl150,071,597 - 51,381,376 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,954,154 - 51,268,026 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0149,824,568 - 51,126,809 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0150,440,798 - 51,751,574 (-)NCBIUU_Cfam_GSD_1.0
Prkn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,866,545 - 145,855,394 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648912,120,678 - 13,327,872 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648912,118,538 - 12,913,664 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15,465,312 - 6,730,872 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115,698,508 - 6,731,132 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.217,649,954 - 8,260,243 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.217,197,051 - 7,562,040 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11388,856,056 - 90,329,379 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604061,183,625 - 62,136,281 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624855430,260 - 1,989,747 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624855430,148 - 1,992,121 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prkn
37267 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:257
Count of miRNA genes:230
Interacting mature miRNAs:245
Transcripts:ENSMUST00000066658, ENSMUST00000168593
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120975022Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120975022Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17787584329487423Mouse
13824987Flal1_mfatty liver accumulation QTL 1, females only (mouse)17821883211218887Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142507Obrq13_mobesity resistance QTL 13 (mouse)Not determined1219832925076769Mouse

Markers in Region
AB019558  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,061,679 - 12,061,794UniSTSGRCm38
MGSCv371712,254,545 - 12,254,660UniSTSGRCm37
Celera1712,091,177 - 12,091,292UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Whitehead/MRC_RH17207.38UniSTS
44.MMHAP58FRG11.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381710,855,914 - 10,856,104UniSTSGRCm38
MGSCv371711,048,780 - 11,048,970UniSTSGRCm37
Celera1710,896,539 - 10,896,729UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Whitehead_YAC13 UniSTS
MHAa35a10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381711,714,548 - 11,714,618UniSTSGRCm38
MGSCv371711,907,414 - 11,907,484UniSTSGRCm37
Celera1711,754,666 - 11,754,736UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Whitehead_YAC17 UniSTS
D17Mit113  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381711,979,442 - 11,979,566UniSTSGRCm38
MGSCv371712,172,308 - 12,172,432UniSTSGRCm37
Celera1712,016,727 - 12,016,829UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
cM Map176.5UniSTS
Whitehead Genetic172.2UniSTS
Whitehead/MRC_RH17203.09UniSTS
D17Mit156  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381710,987,597 - 10,987,721UniSTSGRCm38
MGSCv371711,180,463 - 11,180,587UniSTSGRCm37
Celera1713,597,645 - 13,597,769UniSTS
Celera1711,027,766 - 11,027,884UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
cM Map177.1UniSTS
Whitehead Genetic171.1UniSTS
D9Mit34.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map2C1.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map1E3UniSTS
Cytogenetic Map5E1UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map16B3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map19D3UniSTS
Cytogenetic Map1H5UniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map9DUniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map17DUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map13A1UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map12A3UniSTS
Cytogenetic Map1H2.1UniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map7B1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map2C2UniSTS
Cytogenetic Map19CUniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map5A1UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map13A5UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map3A3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map8CUniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map1H1UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map5G1.3UniSTS
Cytogenetic Map7D1-E2UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map1H2.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map15F2UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map1H4-H6UniSTS
Cytogenetic Map12D2UniSTS
Cytogenetic Map1G3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map1H3UniSTS
Cytogenetic Map19BUniSTS
cM Map950.0UniSTS
Whitehead Genetic943.7UniSTS
Park2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,062,436 - 12,063,009UniSTSGRCm38
MGSCv371712,255,302 - 12,255,875UniSTSGRCm37
Celera1712,091,934 - 12,092,507UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
cM Map17 UniSTS
UniSTS:237570  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381711,546,333 - 11,546,618UniSTSGRCm38
MGSCv371711,739,199 - 11,739,484UniSTSGRCm37
Celera1711,584,063 - 11,584,350UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
UniSTS:237571  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381711,547,267 - 11,547,526UniSTSGRCm38
MGSCv371711,740,133 - 11,740,392UniSTSGRCm37
Celera1711,584,998 - 11,585,257UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
D17Ertd648e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381711,863,089 - 11,863,304UniSTSGRCm38
MGSCv371712,055,955 - 12,056,170UniSTSGRCm37
Celera1711,899,614 - 11,899,829UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
cM Map175.0UniSTS
UniSTS:225174  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381711,978,351 - 11,978,501UniSTSGRCm38
MGSCv371712,171,217 - 12,171,367UniSTSGRCm37
Celera1712,015,598 - 12,015,748UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
D17Jcs117  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381710,855,525 - 10,855,843UniSTSGRCm38
MGSCv371711,048,391 - 11,048,709UniSTSGRCm37
Celera1710,896,152 - 10,896,468UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
cM Map17 UniSTS
D17Jcs70  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381711,775,898 - 11,776,230UniSTSGRCm38
MGSCv371711,968,764 - 11,969,096UniSTSGRCm37
Celera1711,812,532 - 11,812,882UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
cM Map17 UniSTS
D17Jcs72  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381711,519,923 - 11,520,095UniSTSGRCm38
MGSCv371711,712,789 - 11,712,961UniSTSGRCm37
Celera1711,557,608 - 11,557,780UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
cM Map17 UniSTS
D17Jcs75  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381710,995,515 - 10,995,719UniSTSGRCm38
MGSCv371711,188,381 - 11,188,585UniSTSGRCm37
Celera1713,605,631 - 13,605,837UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
cM Map17 UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS
Park2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A3.2-A3.3UniSTS
Park2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A3.2-A3.3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001317726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_016694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB019558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC093450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC109610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC113265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC118545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC163687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02169967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02169968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02169971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02169972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02169979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02169986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF250293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF250294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF250295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF489957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK015990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC113204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT009575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ555554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ555555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ555556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ555557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU272056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000066658
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,271 - 11,776,121 (+)Ensembl
GRCm38.p6 Ensembl1710,840,384 - 11,557,234 (+)Ensembl
RefSeq Acc Id: ENSMUST00000097413
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,278 - 11,164,299 (+)Ensembl
GRCm38.p6 Ensembl1710,840,391 - 10,945,412 (+)Ensembl
RefSeq Acc Id: ENSMUST00000168593   ⟹   ENSMUSP00000127455
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,286,012 - 11,712,060 (+)Ensembl
GRCm38.p6 Ensembl1711,067,125 - 11,493,173 (+)Ensembl
RefSeq Acc Id: ENSMUST00000179624   ⟹   ENSMUSP00000136268
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1712,057,489 - 12,086,448 (+)Ensembl
GRCm38.p6 Ensembl1711,838,602 - 11,867,561 (+)Ensembl
RefSeq Acc Id: ENSMUST00000186167
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,271 - 11,776,121 (+)Ensembl
GRCm38.p6 Ensembl1710,840,384 - 11,557,234 (+)Ensembl
RefSeq Acc Id: ENSMUST00000186406   ⟹   ENSMUSP00000140217
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,522,534 - 11,829,832 (+)Ensembl
GRCm38.p6 Ensembl1711,303,647 - 11,610,945 (+)Ensembl
RefSeq Acc Id: ENSMUST00000190849
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1712,064,097 - 12,086,448 (+)Ensembl
GRCm38.p6 Ensembl1711,845,210 - 11,867,561 (+)Ensembl
RefSeq Acc Id: ENSMUST00000190894
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1712,248,803 - 12,282,245 (+)Ensembl
GRCm38.p6 Ensembl1712,029,916 - 12,063,358 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191124   ⟹   ENSMUSP00000140587
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,271 - 12,282,248 (+)Ensembl
GRCm38.p6 Ensembl1710,840,384 - 12,063,361 (+)Ensembl
RefSeq Acc Id: ENSMUST00000218435   ⟹   ENSMUSP00000151830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,286,012 - 11,854,333 (+)Ensembl
GRCm38.p6 Ensembl1711,067,125 - 11,635,446 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233294   ⟹   ENSMUSP00000156589
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,300 - 12,280,565 (+)Ensembl
GRCm38.p6 Ensembl1710,840,413 - 12,061,678 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233411   ⟹   ENSMUSP00000156556
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,300 - 12,280,565 (+)Ensembl
GRCm38.p6 Ensembl1710,840,413 - 12,061,678 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233436   ⟹   ENSMUSP00000156432
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,300 - 12,280,565 (+)Ensembl
GRCm38.p6 Ensembl1710,840,413 - 12,061,678 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233634   ⟹   ENSMUSP00000156481
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,300 - 12,280,565 (+)Ensembl
GRCm38.p6 Ensembl1710,840,413 - 12,061,678 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233706   ⟹   ENSMUSP00000156810
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,357 - 12,280,565 (+)Ensembl
GRCm38.p6 Ensembl1710,840,470 - 12,061,678 (+)Ensembl
RefSeq Acc Id: ENSMUST00000233782   ⟹   ENSMUSP00000156534
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1711,059,274 - 11,456,397 (+)Ensembl
GRCm38.p6 Ensembl1710,840,387 - 11,237,510 (+)Ensembl
RefSeq Acc Id: NM_001317726   ⟹   NP_001304655
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,260 - 11,776,148 (+)NCBI
GRCm381710,840,359 - 11,557,261 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001403470   ⟹   NP_001390399
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,260 - 12,282,251 (+)NCBI
RefSeq Acc Id: NM_016694   ⟹   NP_057903
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,260 - 12,282,251 (+)NCBI
GRCm381710,840,359 - 12,063,366 (+)NCBI
MGSCv371711,033,250 - 12,256,227 (+)RGD
Celera1710,880,667 - 12,092,859 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523337   ⟹   XP_006523400
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,520,069 - 12,282,257 (+)NCBI
GRCm381711,301,178 - 12,063,370 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006523339   ⟹   XP_006523402
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,305 - 12,282,257 (+)NCBI
GRCm381710,840,421 - 12,063,370 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017317572   ⟹   XP_017173061
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,233 - 12,249,298 (+)NCBI
GRCm381710,840,384 - 12,030,361 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017317573   ⟹   XP_017173062
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,520,069 - 12,282,257 (+)NCBI
GRCm381711,301,178 - 12,063,370 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017317576   ⟹   XP_017173065
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,233 - 11,662,098 (+)NCBI
GRCm381710,840,421 - 11,442,801 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030249894   ⟹   XP_030105754
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,227 - 11,779,751 (+)NCBI
GRCm381710,840,421 - 11,560,864 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036160682   ⟹   XP_036016575
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,399,145 - 12,282,257 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036160683   ⟹   XP_036016576
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,231 - 11,656,356 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036160684   ⟹   XP_036016577
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,233 - 11,738,954 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004939549
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,233 - 12,282,257 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004939550
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391711,059,233 - 12,282,251 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001304655 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390399 (Get FASTA)   NCBI Sequence Viewer  
  NP_057903 (Get FASTA)   NCBI Sequence Viewer  
  XP_006523400 (Get FASTA)   NCBI Sequence Viewer  
  XP_006523402 (Get FASTA)   NCBI Sequence Viewer  
  XP_017173061 (Get FASTA)   NCBI Sequence Viewer  
  XP_017173062 (Get FASTA)   NCBI Sequence Viewer  
  XP_017173065 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105754 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016575 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016576 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016577 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG13890 (Get FASTA)   NCBI Sequence Viewer  
  AAG13891 (Get FASTA)   NCBI Sequence Viewer  
  AAG13892 (Get FASTA)   NCBI Sequence Viewer  
  AAI13205 (Get FASTA)   NCBI Sequence Viewer  
  AAM48109 (Get FASTA)   NCBI Sequence Viewer  
  AAP94053 (Get FASTA)   NCBI Sequence Viewer  
  AAP94054 (Get FASTA)   NCBI Sequence Viewer  
  ACL93281 (Get FASTA)   NCBI Sequence Viewer  
  ACL93282 (Get FASTA)   NCBI Sequence Viewer  
  ACL93283 (Get FASTA)   NCBI Sequence Viewer  
  ADB99567 (Get FASTA)   NCBI Sequence Viewer  
  BAA82404 (Get FASTA)   NCBI Sequence Viewer  
  BAB30069 (Get FASTA)   NCBI Sequence Viewer  
  BAE23371 (Get FASTA)   NCBI Sequence Viewer  
  EDL02077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000127455.3
  ENSMUSP00000136268.2
  ENSMUSP00000140217.2
  ENSMUSP00000140587
  ENSMUSP00000140587.2
  ENSMUSP00000151830.2
  ENSMUSP00000156432.2
  ENSMUSP00000156481.2
  ENSMUSP00000156534.2
  ENSMUSP00000156556.2
  ENSMUSP00000156589
  ENSMUSP00000156589.2
  ENSMUSP00000156810
  ENSMUSP00000156810.2
GenBank Protein Q9WVS6 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_057903   ⟸   NM_016694
- Peptide Label: isoform 1
- UniProtKB: Q9ES22 (UniProtKB/Swiss-Prot),   Q2KHJ9 (UniProtKB/Swiss-Prot),   Q9ES23 (UniProtKB/Swiss-Prot),   Q9WVS6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006523402   ⟸   XM_006523339
- Peptide Label: isoform X6
- UniProtKB: A0A3B2W489 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523400   ⟸   XM_006523337
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001304655   ⟸   NM_001317726
- Peptide Label: isoform 2
- UniProtKB: F6TNF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173061   ⟸   XM_017317572
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017173065   ⟸   XM_017317576
- Peptide Label: isoform X9
- UniProtKB: B8YP90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173062   ⟸   XM_017317573
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_030105754   ⟸   XM_030249894
- Peptide Label: isoform X8
- UniProtKB: F6TNF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000151830   ⟸   ENSMUST00000218435
RefSeq Acc Id: ENSMUSP00000140217   ⟸   ENSMUST00000186406
RefSeq Acc Id: ENSMUSP00000140587   ⟸   ENSMUST00000191124
RefSeq Acc Id: ENSMUSP00000136268   ⟸   ENSMUST00000179624
RefSeq Acc Id: ENSMUSP00000156432   ⟸   ENSMUST00000233436
RefSeq Acc Id: ENSMUSP00000156556   ⟸   ENSMUST00000233411
RefSeq Acc Id: ENSMUSP00000156810   ⟸   ENSMUST00000233706
RefSeq Acc Id: ENSMUSP00000156534   ⟸   ENSMUST00000233782
RefSeq Acc Id: ENSMUSP00000156481   ⟸   ENSMUST00000233634
RefSeq Acc Id: ENSMUSP00000156589   ⟸   ENSMUST00000233294
RefSeq Acc Id: ENSMUSP00000127455   ⟸   ENSMUST00000168593
RefSeq Acc Id: XP_036016576   ⟸   XM_036160683
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036016577   ⟸   XM_036160684
- Peptide Label: isoform X10
- UniProtKB: F6TNF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016575   ⟸   XM_036160682
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001390399   ⟸   NM_001403470
- Peptide Label: isoform 3
Protein Domains
Parkin RING/Ubox like zinc-binding   RING-type   Ubiquitin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WVS6-F1-model_v2 AlphaFold Q9WVS6 1-464 view protein structure

Promoters
RGD ID:13674736
Promoter ID:EPDNEW_M21517
Type:initiation region
Name:Park2_1
Description:Mus musculus Parkinson disease (autosomal recessive, juvenile)2, parkin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21518  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381710,840,391 - 10,840,451EPDNEW
RGD ID:13674738
Promoter ID:EPDNEW_M21518
Type:single initiation site
Name:Park2_2
Description:Mus musculus Parkinson disease (autosomal recessive, juvenile)2, parkin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21517  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381711,013,339 - 11,013,399EPDNEW
RGD ID:6828439
Promoter ID:MM_KWN:22102
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000097413,   NM_016694,   OTTMUST00000077414,   UC008AKJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361711,032,571 - 11,033,422 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1355296 AgrOrtholog
Ensembl Genes ENSMUSG00000023826 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000168593.9 UniProtKB/TrEMBL
  ENSMUST00000179624.8 UniProtKB/TrEMBL
  ENSMUST00000186167 ENTREZGENE
  ENSMUST00000186406.2 UniProtKB/TrEMBL
  ENSMUST00000191124 ENTREZGENE
  ENSMUST00000191124.7 UniProtKB/Swiss-Prot
  ENSMUST00000218435.2 UniProtKB/TrEMBL
  ENSMUST00000233294 ENTREZGENE
  ENSMUST00000233294.2 UniProtKB/TrEMBL
  ENSMUST00000233411.2 UniProtKB/TrEMBL
  ENSMUST00000233436.2 UniProtKB/TrEMBL
  ENSMUST00000233634.2 UniProtKB/TrEMBL
  ENSMUST00000233706 ENTREZGENE
  ENSMUST00000233706.2 UniProtKB/TrEMBL
  ENSMUST00000233782.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1750 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.20.25.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BRcat_RBR_parkin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  E3_UB_ligase_RBR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IBR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Parkin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Parkin_Znf-RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rcat_RBR_parkin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING-HC_RBR_parkin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRIAD_supradom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquilin UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/Swiss-Prot
  Znf-RING_14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:50873 UniProtKB/Swiss-Prot
MGD MGI:1355296 ENTREZGENE
NCBI Gene 50873 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE PARKIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUILIN UniProtKB/TrEMBL
  UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam IBR UniProtKB/TrEMBL
  ubiquitin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-RING_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-RING_14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prkn PhenoGen
PIRSF Parkin UniProtKB/Swiss-Prot
PRINTS PARKIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TRIAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IBR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBQ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WQJ2_MOUSE UniProtKB/TrEMBL
  A0A1W2P7W2_MOUSE UniProtKB/TrEMBL
  A0A3B2W3P9_MOUSE UniProtKB/TrEMBL
  A0A3B2W489 ENTREZGENE, UniProtKB/TrEMBL
  B8YP88_MOUSE UniProtKB/TrEMBL
  B8YP89_MOUSE UniProtKB/TrEMBL
  B8YP90 ENTREZGENE, UniProtKB/TrEMBL
  D3JSV6_MOUSE UniProtKB/TrEMBL
  F6TNF2 ENTREZGENE, UniProtKB/TrEMBL
  J3QMF8_MOUSE UniProtKB/TrEMBL
  PRKN_MOUSE UniProtKB/Swiss-Prot
  Q2KHJ9 ENTREZGENE
  Q3UVA0_MOUSE UniProtKB/TrEMBL
  Q9ES22 ENTREZGENE
  Q9ES23 ENTREZGENE
  Q9WVS6 ENTREZGENE
UniProt Secondary Q2KHJ9 UniProtKB/Swiss-Prot
  Q9ES22 UniProtKB/Swiss-Prot
  Q9ES23 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-05 Prkn  parkin RBR E3 ubiquitin protein ligase  Park2  Parkinson disease (autosomal recessive, juvenile) 2, parkin  Symbol and/or name change 5135510 APPROVED