Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
go back to main search page
Accession:GO:1902237 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
Synonyms:exact_synonym: positive regulation of ER stress-induced apoptosis;   positive regulation of apoptosis in response to ER stress;   positive regulation of apoptosis triggered by ER stress;   positive regulation of endoplasmic reticulum stress-induced apoptosis;   positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   positive regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress;   up regulation of ER stress-induced apoptosis;   up regulation of apoptosis in response to ER stress;   up regulation of apoptosis triggered by ER stress;   up regulation of endoplasmic reticulum stress-induced apoptosis;   up regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   up regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress;   upregulation of ER stress-induced apoptosis;   upregulation of apoptosis in response to ER stress;   upregulation of apoptosis triggered by ER stress;   upregulation of endoplasmic reticulum stress-induced apoptosis;   upregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   upregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress
 narrow_synonym: activation of ER stress-induced apoptosis;   activation of apoptosis in response to ER stress;   activation of apoptosis triggered by ER stress;   activation of endoplasmic reticulum stress-induced apoptosis;   activation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   activation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress


show annotations for term's descendants           Sort by:
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(MGI:5648772|PMID:26015568), (MGI:5796067|PMID:26949185)		 UniProt
RGD		 PMID:26015568 PMID:26949185 GO_REF:0000024 MGI:5648772 MGI:5796067 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:1913418 (PMID:22240901) RGD PMID:22240901 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA		 (PMID:14676213)
UniProtKB:O55033 (MGI:5613475|PMID:16835242)
GO_REF:0000033		 RGD
GO_Central		 PMID:14676213 PMID:16835242 GO_REF:0000033 MGI:5613475 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA		 UniProtKB:Q99M51 (MGI:5613475|PMID:16835242)
GO_REF:0000033		 RGD
GO_Central		 PMID:16835242 GO_REF:0000033 MGI:5613475 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA		 (MGI:5619464|PMID:21216966)
GO_REF:0000107		 RGD
Ensembl		 PMID:21216966 GO_REF:0000107 MGI:5619464 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO
IBA		 (PMID:29507230)
GO_REF:0000033		 RGD
GO_Central		 PMID:29507230 GO_REF:0000033 NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191 		JBrowse link
G Serinc3 serine incorporator 3 acts_upstream_of_or_within ISO (PMID:12486168) RGD PMID:12486168 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:5607229|PMID:20955178)
GO_REF:0000107		 RGD
Ensembl		 PMID:20955178 GO_REF:0000107 MGI:5607229 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of_or_within ISO MGI:102851 (PMID:20811152) RGD PMID:20811152 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    positive regulation of biological process 6650
      positive regulation of response to stimulus 2486
        positive regulation of response to endoplasmic reticulum stress 36
          positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 9
Path 2
Term Annotations click to browse term
  biological_process 19694
    biological regulation 13309
      regulation of biological process 12906
        regulation of cellular process 12363
          signal transduction 7020
            apoptotic signaling pathway 671
              regulation of apoptotic signaling pathway 452
                positive regulation of apoptotic signaling pathway 185
                  positive regulation of intrinsic apoptotic signaling pathway 76
                    positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 9
paths to the root