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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
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Accession:GO:0043154 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
Synonyms:exact_synonym: down regulation of caspase activity;   downregulation of caspase activity;   negative regulation of caspase activation
 narrow_synonym: inhibition of caspase activation;   inhibition of caspase activity
 broad_synonym: negative regulation of caspase activity
 alt_id: GO:0001719



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negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO RGD PMID:15211592 RGD:1625666 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO caspase 3 RGD PMID:18348079 RGD:2313324 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536
JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:19171933 RGD:5510006 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G EP300 E1A binding protein p300 ISO cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077
JBrowse link
G GPI glucose-6-phosphate isomerase ISO RGD PMID:12615053 RGD:1600634 NCBI chr19:34,359,718...34,402,413
Ensembl chr19:34,359,480...34,402,413
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 ISO RGD PMID:15102845 RGD:1304324 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864
JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:21874357 RGD:150540304 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B ISO reduced cleavage of Casp8 and Casp9 in brain following hypoxic/ischemic injury RGD PMID:16397188 RGD:1626654 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G IL6 interleukin 6 ISO RGD PMID:19061939 RGD:2306937 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
JBrowse link
G POR cytochrome p450 oxidoreductase ISO caspase-3 RGD PMID:19264869 RGD:2316785 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855
JBrowse link
G PTMA prothymosin alpha ISO RGD PMID:12522243 RGD:734494 NCBI chr 2:231,708,525...231,713,551
Ensembl chr 2:231,706,895...231,713,551
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    cellular process 18233
      negative regulation of cellular process 6046
        negative regulation of programmed cell death 1159
          negative regulation of apoptotic process 1118
            negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 12
              inhibition of cysteine-type endopeptidase activity involved in apoptotic process 0
              negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 0
              negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 0
Path 2
Term Annotations click to browse term
  biological_process 19613
    biological regulation 13363
      regulation of biological process 12979
        regulation of metabolic process 7321
          regulation of macromolecule metabolic process 6733
            regulation of protein metabolic process 2005
              regulation of proteolysis 431
                regulation of peptidase activity 36
                  regulation of endopeptidase activity 36
                    regulation of cysteine-type endopeptidase activity 30
                      regulation of cysteine-type endopeptidase activity involved in apoptotic process 27
                        negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 12
                          inhibition of cysteine-type endopeptidase activity involved in apoptotic process 0
                          negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 0
                          negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 0
paths to the root