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ONTOLOGY REPORT - ANNOTATIONS

Term:activation of Janus kinase activity
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Accession:GO:0042976 term browser browse the term
Definition:The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
Synonyms:exact_synonym: activation of JAK protein;   activation of JAK protein by tyrosine phosphorylation
 narrow_synonym: activation of JAK1 kinase activity;   activation of JAK1 protein;   activation of JAK2 kinase activity;   activation of JAK2 protein;   tyrosine phosphorylation of JAK1 protein;   tyrosine phosphorylation of JAK2 protein
 broad_synonym: positive regulation of JAK protein activity by tyrosine phosphorylation
 related_synonym: tyrosine phosphorylation of JAK protein
 alt_id: GO:0010531;   GO:0042977


show annotations for term's descendants           Sort by:
activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:9314843 RGD:6478796 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ghr growth hormone receptor IDA RGD PMID:11244571 RGD:1624962 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Prl3d4 prolactin family 3, subfamily D, member 4 IMP RGD PMID:8822264 RGD:1298822 NCBI chr17:37,325,804...37,332,641
Ensembl chr17:37,325,806...37,332,667 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:11818507 RGD:633057 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf4a hepatocyte nuclear factor 4, alpha IDA RGD PMID:16584384 RGD:1625011 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    cellular process 18196
      signal transduction 7020
        positive regulation of signal transduction 1713
          positive regulation of receptor signaling pathway via STAT 71
            positive regulation of receptor signaling pathway via JAK-STAT 65
              activation of Janus kinase activity 5
                negative regulation of activation of Janus kinase activity 1
                positive regulation of activation of Janus kinase activity 0
                regulation of activation of Janus kinase activity + 1
Path 2
Term Annotations click to browse term
  biological_process 19694
    biological regulation 13309
      regulation of biological process 12906
        regulation of metabolic process 6432
          regulation of cellular metabolic process 5821
            regulation of phosphorus metabolic process 906
              regulation of phosphate metabolic process 903
                regulation of phosphorylation 743
                  regulation of protein phosphorylation 710
                    positive regulation of protein phosphorylation 495
                      positive regulation of protein kinase activity 40
                        activation of protein kinase activity 12
                          activation of Janus kinase activity 5
                            negative regulation of activation of Janus kinase activity 1
                            positive regulation of activation of Janus kinase activity 0
                            regulation of activation of Janus kinase activity + 1
paths to the root