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ONTOLOGY REPORT - ANNOTATIONS

Term:transcription factor TFIID complex
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Accession:GO:0005669 term browser browse the term
Definition:A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.


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transcription factor TFIID complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit part_of IEA Ensembl GO_REF:0000107 NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819 		JBrowse link
G ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit part_of IEA Ensembl GO_REF:0000107 NCBI chr2B:32,983,492...33,020,492
Ensembl chr2B:127,922,483...127,959,372 		JBrowse link
G GTF2A1 general transcription factor IIA subunit 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr14:61,751,492...61,797,083
Ensembl chr14:80,951,886...80,996,777 		JBrowse link
G GTF2A2 general transcription factor IIA subunit 2 part_of IEA Ensembl GO_REF:0000107 NCBI chr15:38,608,360...38,627,156
Ensembl chr15:56,913,452...56,932,052 		JBrowse link
G GTF2B general transcription factor IIB part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:91,568,296...91,607,467
Ensembl chr 1:90,319,637...90,359,134 		JBrowse link
G GTF2E1 general transcription factor IIE subunit 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 3:117,850,234...117,890,719
Ensembl chr 3:124,760,926...124,801,230 		JBrowse link
G GTF2E2 general transcription factor IIE subunit 2 part_of IEA Ensembl GO_REF:0000107 NCBI chr 8:29,881,879...29,961,554
Ensembl chr 8:27,071,634...27,151,147 		JBrowse link
G GTF2F1 general transcription factor IIF subunit 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr19:5,401,090...5,414,142
Ensembl chr19:6,323,780...6,336,215 		JBrowse link
G GTF2H3 general transcription factor IIH subunit 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr12:121,218,813...121,246,807
Ensembl chr12:125,445,381...125,473,763 		JBrowse link
G GTF2H4 general transcription factor IIH subunit 4 part_of IEA Ensembl GO_REF:0000107 NCBI chr 6:30,653,398...30,659,316
Ensembl chr 6:31,521,501...31,527,456 		JBrowse link
G GTF2H5 general transcription factor IIH subunit 5 part_of IEA Ensembl GO_REF:0000107 Ensembl chr 6:158,126,665...158,153,663 JBrowse link
G LOC100987487 general transcription factor IIH subunit 2 part_of ISO (PMID:27193682) UniProt PMID:27193682 NCBI chr 5:44,412,653...44,445,158 JBrowse link
G SUPT3H SPT3 homolog, SAGA and STAGA complex component part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 6:44,406,978...44,960,039 JBrowse link
G TAF1 TATA-box binding protein associated factor 1 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
InterPro
UniProt
Ensembl		 PMID:23332750 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:60,630,137...60,729,904
Ensembl chr  X:70,684,217...70,782,323 		JBrowse link
G TAF10 TATA-box binding protein associated factor 10 part_of
located_in		 ISO (PMID:14580349), (PMID:15099517), (PMID:29111974), (PMID:7729427), (PMID:7923369)
(PMID:23332750)		 MGI
ComplexPortal		 PMID:7729427 PMID:7923369 PMID:14580349 PMID:15099517 PMID:23332750 More... NCBI chr11:6,742,862...6,744,260 JBrowse link
G TAF11 TATA-box binding protein associated factor 11 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
InterPro
Ensembl		 PMID:23332750 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:34,439,369...34,449,501
Ensembl chr 6:35,536,614...35,546,805 		JBrowse link
G TAF12 TATA-box binding protein associated factor 12 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
InterPro		 PMID:23332750 GO_REF:0000002 GO_REF:0000118 NCBI chr 1:27,874,675...27,914,672 JBrowse link
G TAF13 TATA-box binding protein associated factor 13 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
Ensembl		 PMID:23332750 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:111,441,202...111,452,773
Ensembl chr 1:110,604,654...110,617,808 		JBrowse link
G TAF1L TATA-box binding protein associated factor 1 like part_of IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr 9:32,403,835...32,409,767
Ensembl chr 9:33,216,048...33,221,525 		JBrowse link
G TAF2 TATA-box binding protein associated factor 2 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
InterPro
Ensembl		 PMID:23332750 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:116,421,520...116,523,138
Ensembl chr 8:119,170,327...119,271,405 		JBrowse link
G TAF3 TATA-box binding protein associated factor 3 part_of
located_in		 ISO (PMID:11438666), (PMID:29111974)
(PMID:23332750)		 MGI
ComplexPortal		 PMID:11438666 PMID:23332750 PMID:29111974 NCBI chr10:7,851,294...8,047,100 JBrowse link
G TAF4 TATA-box binding protein associated factor 4 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
InterPro		 PMID:23332750 GO_REF:0000002 GO_REF:0000118 NCBI chr20:58,341,086...58,431,623 JBrowse link
G TAF4B TATA-box binding protein associated factor 4b part_of IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr18:19,480,844...19,648,936
Ensembl chr18:23,089,736...23,254,518 		JBrowse link
G TAF5 TATA-box binding protein associated factor 5 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
Ensembl		 PMID:23332750 GO_REF:0000107 GO_REF:0000118 NCBI chr10:99,965,537...99,986,955
Ensembl chr10:103,426,334...103,447,046 		JBrowse link
G TAF6 TATA-box binding protein associated factor 6 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
InterPro
Ensembl		 PMID:23332750 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:92,142,646...92,154,951
Ensembl chr 7:105,575,861...105,588,142 		JBrowse link
G TAF6L TATA-box binding protein associated factor 6 like part_of IEA InterPro GO_REF:0000002 NCBI chr11:58,126,480...58,142,752
Ensembl chr11:61,485,259...61,495,877 		JBrowse link
G TAF7 TATA-box binding protein associated factor 7 part_of
located_in		 ISO (PMID:14580349), (PMID:24927529), (PMID:25412659), (PMID:27007846), (PMID:29111974), (PMID:7824954)
(PMID:10438527), (PMID:28893950)
(PMID:23332750)		 ParkinsonsUK-UCL
MGI
ComplexPortal		 PMID:7824954 PMID:10438527 PMID:14580349 PMID:23332750 PMID:24927529 More... NCBI chr 5:136,680,554...136,682,862 JBrowse link
G TAF7L TATA-box binding protein associated factor 7 like part_of IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr  X:90,471,354...90,496,618
Ensembl chr  X:100,607,488...100,631,301 		JBrowse link
G TAF8 TATA-box binding protein associated factor 8 located_in
part_of		 ISO
IEA		 (PMID:23332750) ComplexPortal
TreeGrafter
InterPro		 PMID:23332750 GO_REF:0000002 GO_REF:0000118 NCBI chr 6:41,631,483...41,672,988
Ensembl chr 6:42,933,107...42,978,271 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 part_of
located_in		 ISO (PMID:14580349), (PMID:15899866), (PMID:29111974)
(PMID:23332750)		 ARUK-UCL
ComplexPortal		 PMID:14580349 PMID:15899866 PMID:23332750 PMID:29111974 NCBI chr 5:44,630,503...44,635,760 JBrowse link
G TAF9B TATA-box binding protein associated factor 9b part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:67,305,754...67,315,714
Ensembl chr  X:77,417,232...77,427,193 		JBrowse link
G TBP TATA-box binding protein part_of
located_in		 ISO
IEA		 (PMID:23332750) RGD
Ensembl
ComplexPortal		 PMID:7980586 PMID:23332750 GO_REF:0000107 RGD:2306552 NCBI chr 6:168,714,214...168,732,744
Ensembl chr 6:173,800,240...173,826,909 		JBrowse link
G TCEA1 transcription elongation factor A1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 8:50,393,553...50,449,698
Ensembl chr 8:47,770,661...47,825,804 		JBrowse link
G WDR38 WD repeat domain 38 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 9:95,973,932...95,978,398
Ensembl chr 9:124,491,733...124,496,133 		JBrowse link
G WDR5 WD repeat domain 5 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 9:105,241,415...105,265,925
Ensembl chr 9:133,848,185...133,872,889 		JBrowse link
G WDR86 WD repeat domain 86 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 7:142,962,837...142,997,810
Ensembl chr 7:155,118,575...155,147,724 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17180
    cellular anatomical entity 16965
      nucleoplasm 3511
        RNA polymerase II, holoenzyme 68
          transcription factor TFIID complex 36
            TAF4B-containing transcription factor TFIID complex 0
Path 2
Term Annotations click to browse term
  cellular_component 17180
    cellular anatomical entity 16965
      organelle 12482
        membrane-bounded organelle 11391
          intracellular membrane-bounded organelle 10860
            nucleus 6800
              nuclear protein-containing complex 1235
                nuclear DNA-directed RNA polymerase complex 93
                  RNA polymerase II, holoenzyme 68
                    transcription factor TFIID complex 36
                      TAF4B-containing transcription factor TFIID complex 0
paths to the root