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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cytokine production involved in immune response
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Accession:GO:0002719 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.
Synonyms:narrow_synonym: negative regulation of cytokine biosynthetic process involved in immune response;   negative regulation of cytokine secretion involved in immune response
 related_synonym: down regulation of cytokine production during immune response;   downregulation of cytokine production during immune response;   inhibition of cytokine production during immune response;   negative regulation of cytokine production during immune response
 alt_id: GO:0002740;   GO:0002743


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negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 acts_upstream_of_or_within IDA (PMID:20060382) MGI PMID:20060382 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373 		JBrowse link
G Apoa1 apolipoprotein A-I involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Apoa2 apolipoprotein A-II involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948 		JBrowse link
G Il10 interleukin 10 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Mir302a microRNA 302a acts_upstream_of ISO (PMID:29046356) ARUK-UCL PMID:29046356 NCBI chr 3:127,339,145...127,339,213
Ensembl chr 3:127,339,145...127,339,213 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in IMP (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within IMP (PMID:11168643) MGI PMID:11168643 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007 		JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within IMP (PMID:24670807) MGI PMID:24670807 NCBI chr 1:75,157,509...75,168,654
Ensembl chr 1:75,157,504...75,168,840 		JBrowse link
G Axl AXL receptor tyrosine kinase acts_upstream_of_or_within IGI (PMID:16831897) MGI PMID:16831897 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130 		JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within IMP
ISO		 (PMID:24882011) MGI PMID:24882011 GO_REF:0000008 NCBI chr19:46,318,251...46,327,144
Ensembl chr19:46,318,251...46,327,141 		JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within IMP (PMID:16926417) MGI PMID:16926417 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in IMP (MGI:2183694|PMID:12150927) BHF-UCL PMID:12150927 MGI:2183694 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within IMP (PMID:21703540) MGI PMID:21703540 NCBI chr 9:44,164,010...44,179,896
Ensembl chr 9:44,164,014...44,179,896 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within IMP
IDA		 (PMID:15220916) MGI PMID:15220916 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Prg2 proteoglycan 2, bone marrow acts_upstream_of_or_within IMP (PMID:16926417) MGI PMID:16926417 NCBI chr 2:84,810,805...84,813,977
Ensembl chr 2:84,810,805...84,813,976 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815 		JBrowse link
G Twist1 twist basic helix-loop-helix transcription factor 1 acts_upstream_of_or_within IGI (PMID:16831897) MGI PMID:16831897 NCBI chr12:34,007,670...34,009,830
Ensembl chr12:34,007,670...34,009,828 		JBrowse link
G Twist2 twist basic helix-loop-helix transcription factor 2 acts_upstream_of_or_within IGI
IMP		 (PMID:16831897) MGI PMID:16831897 NCBI chr 1:91,729,183...91,775,756
Ensembl chr 1:91,729,183...91,775,750 		JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 B cell leukemia/lymphoma 6 acts_upstream_of_or_within IMP (PMID:15950739) MGI PMID:15950739 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO RGD
MGI		 PMID:17234154 GO_REF:0000096 MGI:4417868 RGD:1601626 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 acts_upstream_of_or_within IMP (PMID:16533754) MGI PMID:16533754 NCBI chr 5:130,200,644...130,243,178
Ensembl chr 5:130,200,639...130,243,183 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 antigen acts_upstream_of_or_within IMP (PMID:24658051) MGI PMID:24658051 NCBI chr16:45,856,015...45,940,611
Ensembl chr16:45,856,020...45,940,614 		JBrowse link
G Gm7030 predicted gene 7030 involved_in ISO (PMID:24018270) UniProt PMID:24018270 NCBI chr17:36,438,501...36,440,317
Ensembl chr17:36,420,611...36,440,317 		JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100 		JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gm7030 predicted gene 7030 involved_in ISO (PMID:24018270) UniProt PMID:24018270 NCBI chr17:36,438,501...36,440,317
Ensembl chr17:36,420,611...36,440,317 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837 		JBrowse link
G Lilrb4a leukocyte immunoglobulin-like receptor, subfamily B, member 4A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707 		JBrowse link
G Lilrb4b leukocyte immunoglobulin-like receptor, subfamily B, member 4B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in IDA (MGI:5700313|PMID:11477403) UniProt PMID:11477403 MGI:5700313 NCBI chr 1:171,594,700...171,628,752
Ensembl chr 1:171,594,695...171,628,752 		JBrowse link
G Smad7 SMAD family member 7 involved_in IMP (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006 		JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within IDA (PMID:21383057) MGI PMID:21383057 NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463 		JBrowse link
G Xcl1 chemokine (C motif) ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chr 1:164,759,216...164,763,094
Ensembl chr 1:164,759,213...164,763,096 		JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase, liver involved_in IMP (MGI:5908339|PMID:19360123) UniProt PMID:19360123 MGI:5908339 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382 		JBrowse link
G Ifnb1 interferon beta 1, fibroblast involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011 		JBrowse link
G Tbx21 T-box 21 involved_in IMP
IDA		 (MGI:5543347|PMID:23616576)
(MGI:1354779|PMID:10761931)		 UniProt PMID:10761931 PMID:23616576 MGI:1354779 MGI:5543347 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28577
    multicellular organismal process 8917
      cytokine production 985
        negative regulation of cytokine production 420
          negative regulation of cytokine production involved in immune response 38
            negative regulation of B cell cytokine production 0
            negative regulation of T cell cytokine production + 12
            negative regulation of dendritic cell cytokine production + 2
            negative regulation of macrophage cytokine production 14
            negative regulation of mast cell cytokine production 3
            negative regulation of natural killer cell cytokine production 2
Path 2
Term Annotations click to browse term
  biological_process 28577
    biological regulation 13126
      regulation of biological process 12731
        regulation of metabolic process 6599
          regulation of biosynthetic process 5426
            regulation of cellular biosynthetic process 5336
              regulation of macromolecule biosynthetic process 5219
                regulation of gene expression 5099
                  regulation of cytokine production 977
                    negative regulation of cytokine production 420
                      negative regulation of cytokine production involved in immune response 38
                        negative regulation of B cell cytokine production 0
                        negative regulation of T cell cytokine production + 12
                        negative regulation of dendritic cell cytokine production + 2
                        negative regulation of macrophage cytokine production 14
                        negative regulation of mast cell cytokine production 3
                        negative regulation of natural killer cell cytokine production 2
paths to the root