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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cytokine production involved in immune response
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Accession:GO:0002719 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.
Synonyms:narrow_synonym: negative regulation of cytokine biosynthetic process involved in immune response;   negative regulation of cytokine secretion involved in immune response
 related_synonym: down regulation of cytokine production during immune response;   downregulation of cytokine production during immune response;   inhibition of cytokine production during immune response;   negative regulation of cytokine production during immune response
 alt_id: GO:0002740;   GO:0002743



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negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 acts_upstream_of_or_within IDA (PMID:20060382) MGI PMID:20060382 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373
JBrowse link
G Apoa1 apolipoprotein A-I involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoa2 apolipoprotein A-II involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948
JBrowse link
G Il10 interleukin 10 involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Mir302a microRNA 302a acts_upstream_of ISO (PMID:29046356) ARUK-UCL PMID:29046356 NCBI chr 3:127,339,145...127,339,213
Ensembl chr 3:127,339,145...127,339,213
JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in IMP (PMID:16020505) BHF-UCL PMID:16020505 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219
JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within IMP (PMID:11168643) MGI PMID:11168643 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within IMP (PMID:24670807) MGI PMID:24670807 NCBI chr 1:75,157,509...75,168,654
Ensembl chr 1:75,157,504...75,168,840
JBrowse link
G Axl AXL receptor tyrosine kinase acts_upstream_of_or_within IGI (PMID:16831897) MGI PMID:16831897 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within IMP
ISO
(PMID:24882011) MGI PMID:24882011 GO_REF:0000008 NCBI chr19:46,318,251...46,327,144
Ensembl chr19:46,318,251...46,327,141
JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within IMP (PMID:16926417) MGI PMID:16926417 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in IMP (PMID:12150927) BHF-UCL PMID:12150927 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035
JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within IMP (PMID:21703540) MGI PMID:21703540 NCBI chr 9:44,164,010...44,179,896
Ensembl chr 9:44,164,014...44,179,896
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within IMP
IDA
(PMID:15220916) MGI PMID:15220916 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
JBrowse link
G Prg2 proteoglycan 2, bone marrow acts_upstream_of_or_within IMP (PMID:16926417) MGI PMID:16926417 NCBI chr 2:84,810,805...84,813,977
Ensembl chr 2:84,810,805...84,813,976
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
GO_Central
AgBase
GO_REF:0000024 GO_REF:0000119 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISS
ISO
AgBase
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815
JBrowse link
G Twist1 twist basic helix-loop-helix transcription factor 1 acts_upstream_of_or_within IGI (PMID:16831897) MGI PMID:16831897 NCBI chr12:34,007,670...34,009,830
Ensembl chr12:34,007,670...34,009,828
JBrowse link
G Twist2 twist basic helix-loop-helix transcription factor 2 acts_upstream_of_or_within IGI
IMP
(PMID:16831897) MGI PMID:16831897 NCBI chr 1:91,729,183...91,775,756
Ensembl chr 1:91,729,183...91,775,750
JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 B cell leukemia/lymphoma 6 acts_upstream_of_or_within IMP (PMID:15950739) MGI PMID:15950739 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO RGD
GO_Central
PMID:17234154 GO_REF:0000096 RGD:1601626 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 acts_upstream_of_or_within IMP (PMID:16533754) MGI PMID:16533754 NCBI chr 5:130,200,644...130,243,178
Ensembl chr 5:130,200,639...130,243,183
JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 antigen acts_upstream_of_or_within IMP (PMID:24658051) MGI PMID:24658051 NCBI chr16:45,856,015...45,940,611
Ensembl chr16:45,856,020...45,940,614
JBrowse link
G Gm7030 predicted gene 7030 involved_in ISO (PMID:24018270) UniProt PMID:24018270 NCBI chr17:36,438,501...36,440,317
Ensembl chr17:36,420,611...36,440,317
JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100
JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Gm7030 predicted gene 7030 involved_in ISO (PMID:24018270) UniProt PMID:24018270 NCBI chr17:36,438,501...36,440,317
Ensembl chr17:36,420,611...36,440,317
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837
JBrowse link
G Lilrb4a leukocyte immunoglobulin-like receptor, subfamily B, member 4A involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707
JBrowse link
G Lilrb4b leukocyte immunoglobulin-like receptor, subfamily B, member 4B involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in IDA (PMID:11477403) UniProt PMID:11477403 NCBI chr 1:171,594,700...171,628,752
Ensembl chr 1:171,594,695...171,628,752
JBrowse link
G Smad7 SMAD family member 7 involved_in IMP (PMID:25642768) BHF-UCL PMID:25642768 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006
JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within IDA (PMID:21383057) MGI PMID:21383057 NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463
JBrowse link
G Xcl1 chemokine (C motif) ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chr 1:164,759,216...164,763,094
Ensembl chr 1:164,759,213...164,763,096
JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase, liver involved_in IMP (PMID:19360123) UniProt PMID:19360123 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
JBrowse link
G Ifnb1 interferon beta 1, fibroblast involved_in ISO GO_Central GO_REF:0000119 NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011
JBrowse link
G Tbx21 T-box 21 involved_in IMP
IDA
(PMID:23616576)
(PMID:10761931)
UniProt PMID:10761931 PMID:23616576 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28715
    multicellular organismal process 9032
      cytokine production 1006
        negative regulation of cytokine production 422
          negative regulation of cytokine production involved in immune response 38
            negative regulation of B cell cytokine production 0
            negative regulation of T cell cytokine production + 12
            negative regulation of dendritic cell cytokine production + 2
            negative regulation of macrophage cytokine production 14
            negative regulation of mast cell cytokine production 3
            negative regulation of natural killer cell cytokine production 2
Path 2
Term Annotations click to browse term
  biological_process 28715
    biological regulation 13502
      regulation of biological process 13070
        regulation of cellular process 12691
          regulation of metabolic process 7049
            regulation of biosynthetic process 5658
              regulation of cellular biosynthetic process 5558
                regulation of macromolecule biosynthetic process 5441
                  regulation of gene expression 5314
                    regulation of cytokine production 998
                      negative regulation of cytokine production 422
                        negative regulation of cytokine production involved in immune response 38
                          negative regulation of B cell cytokine production 0
                          negative regulation of T cell cytokine production + 12
                          negative regulation of dendritic cell cytokine production + 2
                          negative regulation of macrophage cytokine production 14
                          negative regulation of mast cell cytokine production 3
                          negative regulation of natural killer cell cytokine production 2
paths to the root