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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gramine
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Accession:CHEBI:28948 term browser browse the term
Definition:An aminoalkylindole that is indole carrying a dimethylaminomethyl substituent at postion 3.
Synonyms:exact_synonym: 1-(1H-indol-3-yl)-N,N-dimethylmethanamine
 related_synonym: (1H-indol-3-ylmethyl)dimethylamine;   3-(Dimethylaminomethyl)indole;   3-(N,N-Dimethylaminomethyl)indole;   3-[(Dimethylamino)methyl]indole;   Donaxin;   Donaxine;   Formula=C11H14N2;   Gramin;   InChI=1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3;   InChIKey=OCDGBSUVYYVKQZ-UHFFFAOYSA-N;   Indol-3-ylmethyldimethylamine;   N,N-Dimethyl-1H-indole-3-methanamine;   SMILES=C1(=CNC2=C1C=CC=C2)CN(C)C;   beta-Dimethylaminomethylindole
 alt_id: CHEBI:24428;   CHEBI:5531
 xref: CAS:87-52-5;   HMDB:HMDB0035762;   KEGG:C08304;   KNApSAcK:C00001411;   LINCS:LSM-6572
 xref_mesh: MESH:C007884
 xref: MetaCyc:CPD-8915;   PMID:23700450;   PMID:24332729;   PMID:24979400;   PMID:25149234;   PMID:25281166;   PMID:26920698;   PMID:27037659;   PMID:27138201;   PMID:27157767;   PMID:27250087;   PMID:27280380;   PMID:27854190;   PMID:28004092;   Reaxys:140521
 cyclic_relationship: is_conjugate_base_of CHEBI:136516


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gramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 multiple interactions ISO gramine binds to and results in increased activity of ADIPOR1 protein CTD PMID:23691032 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases phosphorylation ISO gramine results in decreased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO gramine results in increased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases phosphorylation ISO gramine results in increased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        antimicrobial agent 18164
          antiviral agent 11074
            gramine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic heterocyclic compound 18874
                                  organic heteropolycyclic compound 18299
                                    organic heterobicyclic compound 17233
                                      benzopyrrole 9722
                                        indoles 9411
                                          aminoalkylindole 524
                                            gramine 4
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