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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Apicularen A
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Accession:CHEBI:199868 term browser browse the term
Synonyms:exact_synonym: (2Z,4Z)-N-[(E)-3-(7,15-dihydroxy-9-oxo-10,17-dioxatricyclo[11.3.1.03,8]heptadeca-3(8),4,6-trien-11-yl)prop-1-enyl]hepta-2,4-dienamide
 related_synonym: Formula=C25H31NO6;   InChI=1S/C25H31NO6/c1-2-3-4-5-11-23(29)26-12-7-9-19-16-21-15-18(27)14-20(31-21)13-17-8-6-10-22(28)24(17)25(30)32-19/h3-8,10-12,18-21,27-28H,2,9,13-16H2,1H3,(H,26,29)/b4-3-,11-5-,12-7+;   InChIKey=MVOORUCGKRDJFW-UYSGNFFCSA-N;   SMILES=O=C1OC(CC2OC(CC=3C1=C(O)C=CC3)CC(C2)O)C/C=C/NC(=O)/C=C\\C=C/CC
 xref: Chemspider:8021854
 xref_mesh: MESH:C117813


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Apicularen A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity ISO apicularen A results in increased activity of JUN protein CTD PMID:15561798 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO apicularen A results in increased phosphorylation of and results in increased expression of MAPK8 protein CTD PMID:15561798 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO apicularen A results in decreased expression of NFKBIA protein CTD PMID:15561798 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO apicularen A results in increased expression of NOS2 mRNA; apicularen A results in increased expression of NOS2 protein CTD PMID:15561798 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    chemical entity 19836
      molecular entity 19836
        polyatomic entity 19794
          heteroatomic molecular entity 19751
            hydroxides 19330
              organic hydroxy compound 18953
                phenols 18636
                  Apicularen A 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic aromatic compound 19366
                                  phenols 18636
                                    Apicularen A 4
paths to the root