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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:CDP
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Accession:CHEBI:17239 term browser browse the term
Definition:A pyrimidine ribonucleoside 5'-diphosphate having cytosine as the nucleobase.
Synonyms:related_synonym: 5'-CDP;   Cytidine 5'-diphosphate;   Cytidine 5'-diphosphoric acid;   Cytidine 5'-pyrophosphate;   Cytidine diphosphate;   Cytidine, 5'-(trihydrogen pyrophosphate);   Formula=C9H15N3O11P2;   InChI=1S/C9H15N3O11P2/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1;   InChIKey=ZWIADYZPOWUWEW-XVFCMESISA-N;   SMILES=Nc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1;   cytidine 5'-(trihydrogen diphosphate)
 alt_id: CHEBI:13254;   CHEBI:23519;   CHEBI:3260;   CHEBI:41451
 xref: CAS:63-38-7;   DrugBank:DB04555;   KEGG:C00112;   PDBeChem:CDF;   PDBeChem:CDP
 cyclic_relationship: is_conjugate_acid_of CHEBI:58069


show annotations for term's descendants           Sort by:
CDP-choline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of CASP3 protein CTD PMID:12443983 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP Cytidine Diphosphate Choline results in decreased expression of ICAM1 mRNA CTD PMID:16193989 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions ISO NCEH1 protein inhibits the reaction [[Chlorpyrifos metabolite co-treated with Cytidine Diphosphate Choline] results in increased abundance of Platelet Activating Factor] CTD PMID:18164358 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form CTD PMID:12443983 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Sirt1 sirtuin 1 increases expression
multiple interactions		 EXP Cytidine Diphosphate Choline results in increased expression of SIRT1 protein
Cytidine Diphosphate Choline results in increased expression of and results in increased activity of SIRT1 protein		 CTD PMID:23600725 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        biochemical role 19522
          metabolite 19509
            prokaryotic metabolite 18587
              bacterial metabolite 18587
                Escherichia coli metabolite 18498
                  CDP 5
                    2'-deoxy-5-hydroxymethyl-CDP 0
                    CDP-1L-myo-inositol 0
                    CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol 0
                    CDP-choline 5
                    CDP-sugar + 0
                    dCDP 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      chalcogen 19543
                        oxygen atom 19518
                          oxygen molecular entity 19518
                            hydroxides 19330
                              oxoacid 18765
                                pnictogen oxoacid 13224
                                  phosphorus oxoacid 12428
                                    phosphoric acids 11428
                                      phosphoric acid 11428
                                        phosphoric acid derivative 11237
                                          phosphate 11236
                                            organic phosphate 11236
                                              carbohydrate phosphate 1856
                                                phospho sugar 1701
                                                  aldose phosphate 1698
                                                    aldopentose phosphate 1690
                                                      ribose phosphate 1685
                                                        ribonucleotide 1646
                                                          ribonucleoside 5'-phosphate 645
                                                            ribonucleoside 5'-diphosphate 114
                                                              pyrimidine ribonucleoside 5'-diphosphate 23
                                                                CDP 5
                                                                  2'-deoxy-5-hydroxymethyl-CDP 0
                                                                  CDP-1L-myo-inositol 0
                                                                  CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol 0
                                                                  CDP-choline 5
                                                                  CDP-sugar + 0
                                                                  dCDP 0
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