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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:oxoicosatetraenoic acid
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Accession:CHEBI:61704 term browser browse the term
Definition:Any C20 polyunsaturated fatty acid having four double bonds and at least one oxo group.
Synonyms:related_synonym: keto-ETE;   keto-ETEs;   ketoeicosatetraenoic acid;   ketoeicosatetraenoic acids;   oxo-ETE;   oxo-ETEs;   oxoETE;   oxoETEs;   oxoeicosatetraenoic acid;   oxoeicosatetraenoic acids;   oxoicosatetraenoic acids
 cyclic_relationship: is_conjugate_acid_of CHEBI:131859


show annotations for term's descendants           Sort by:
15-oxo-ETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO 15-keto-5,8,11,13-eicosatetraenoic acid results in increased expression of HMOX1 protein CTD PMID:25450232 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions
decreases activity		 ISO [15-keto-5,8,11,13-eicosatetraenoic acid results in decreased activity of IKBKB protein] which results in decreased phosphorylation of NFKBIA protein CTD PMID:25450232 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 15-keto-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:25450232 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO 15-keto-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:25450232 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [15-keto-5,8,11,13-eicosatetraenoic acid results in decreased activity of IKBKB protein] which results in decreased phosphorylation of NFKBIA protein CTD PMID:25450232 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 15-keto-5,8,11,13-eicosatetraenoic acid results in increased expression of NQO1 protein CTD PMID:25450232 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions		 ISO 15-keto-5,8,11,13-eicosatetraenoic acid results in decreased expression of TNF mRNA
15-keto-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]		 CTD PMID:25450232 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
5-oxo-ETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 increases secretion ISO 5-oxo-6,8,11,14-eicosatetraenoic acid results in increased secretion of CSF2 protein CTD PMID:15136573 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      atom 19806
        nonmetal atom 19744
          carbon atom 19702
            organic molecular entity 19702
              olefinic compound 16951
                olefinic fatty acid 792
                  oxoicosatetraenoic acid 8
                    11-oxo-ETE + 0
                    12-oxo-ETE 0
                    15-oxo-ETE + 7
                    5-oxo-ETE 1
                    8-oxo-ETE 0
                    9-oxo-ETE 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      monocarboxylic acid 17984
                                        fatty acid 16792
                                          unsaturated fatty acid 1095
                                            polyunsaturated fatty acid 838
                                              oxoicosatetraenoic acid 8
                                                11-oxo-ETE + 0
                                                12-oxo-ETE 0
                                                15-oxo-ETE + 7
                                                5-oxo-ETE 1
                                                8-oxo-ETE 0
                                                9-oxo-ETE 0
paths to the root