CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: triazophos
Accession: CHEBI:38963
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Definition: An organothiophosphate insecticide that has formula C12H16N3O3PS.
Synonyms: exact_synonym: O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) phosphorothioate
related_synonym: 1-Phenyl-1,2,4-triazolyl-3-(O,O-diethylthionophosphate); Formula=C12H16N3O3PS; Hostathion; InChI=1S/C12H16N3O3PS/c1-3-16-19(20,17-4-2)18-12-13-10-15(14-12)11-8-6-5-7-9-11/h5-10H,3-4H2,1-2H3; InChIKey=AMFGTOFWMRQMEM-UHFFFAOYSA-N; Methoxone; O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) thiophosphate; Phosphorothioic acid, O,O-diethyl O-(1-phenyl-1H-1,2,4-triazol-3-yl) ester; SMILES=CCOP(=S)(OCC)Oc1ncn(n1)-c1ccccc1; Triazofos
xref: CAS:24017-47-8; KEGG:C18657
xref_mesh: MESH:C012584
xref: PPDB:653
G
Ache
acetylcholinesterase
decreases activity
ISO
triazophos metabolite results in decreased activity of ACHE protein; triazophos results in decreased activity of ACHE protein
CTD
PMID:33844597
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
G
Bdnf
brain-derived neurotrophic factor
decreases expression
EXP
triazophos results in decreased expression of BDNF mRNA; triazophos results in decreased expression of BDNF protein
CTD
PMID:23949197
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
G
Gip
gastric inhibitory polypeptide
decreases secretion
EXP
triazophos results in decreased secretion of GIP protein
CTD
PMID:34038317
NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503
G
Il6
interleukin 6
decreases secretion
EXP
triazophos results in decreased secretion of IL6 protein
CTD
PMID:34038317
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Lep
leptin
decreases secretion
EXP
triazophos results in decreased secretion of LEP protein
CTD
PMID:34038317
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Pyy
peptide YY
decreases secretion
EXP
triazophos results in decreased secretion of PYY protein
CTD
PMID:34038317
NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
G
Tp53
tumor protein p53
affects activity
ISO
triazophos metabolite affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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