CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1,3,5-triazinylamino nitrile
Accession: CHEBI:38176
browse the term
Definition: Any diamino-1,3,5-triazine in which the amino group is substituted by at least one cyano group.
Synonyms: related_synonym: 1,3,5-triazinylamino nitriles
G
Adra2a
adrenoceptor alpha 2A
affects binding affects activity
EXP
cyanazine binds to ADRA2A protein cyanazine affects the activity of ADRA2A protein
CTD
PMID:11071396
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
G
Dbh
dopamine beta-hydroxylase
increases expression
EXP
cyanazine results in increased expression of DBH protein
CTD
PMID:14550852
NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
G
Drd2
dopamine receptor D2
affects activity
EXP
cyanazine affects the activity of DRD2 protein
CTD
PMID:11071396
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
G
Esr1
estrogen receptor 1
affects binding multiple interactions
ISO
cyanazine binds to ESR1 protein cyanazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]
CTD
PMID:8858116
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Esr2
estrogen receptor 2
affects binding
ISO
cyanazine binds to ESR2 protein
CTD
PMID:12224631
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
G
Gper1
G protein-coupled estrogen receptor 1
affects expression
ISO
cyanazine affects the expression of GPER1 mRNA
CTD
PMID:26955487
NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
G
Pde4a
phosphodiesterase 4A
decreases activity
ISO
cyanazine results in decreased activity of PDE4A protein
CTD
PMID:21251949
NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961
G
Pde5a
phosphodiesterase 5A
affects activity
ISO
cyanazine affects the activity of PDE5 protein
CTD
PMID:21251949
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
G
Prl
prolactin
increases expression
EXP
cyanazine metabolite results in increased expression of PRL protein; cyanazine results in increased expression of PRL protein
CTD
PMID:11071396
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
G
Th
tyrosine hydroxylase
increases expression
EXP
cyanazine results in increased expression of TH protein
CTD
PMID:14550852
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19808
chemical entity
19806
group
19765
pseudohalo group
4566
cyano group
4566
nitrile
4566
1,3,5-triazinylamino nitrile
10
2-\{[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino\}-2-methylbutanenitrile +
0
cyanazine +
10
Path 2
CHEBI ontology
19808
subatomic particle
19806
composite particle
19806
hadron
19806
baryon
19806
nucleon
19806
atomic nucleus
19806
atom
19806
main group element atom
19756
main group molecular entity
19756
s-block molecular entity
19595
hydrogen molecular entity
19582
hydrides
19095
inorganic hydride
18093
pnictogen hydride
18082
nitrogen hydride
17989
azane
17798
ammonia
17797
organic amino compound
17797
polyamine
9021
diamine
8956
diamino-1,3,5-triazine
5102
1,3,5-triazinylamino nitrile
10
2-\{[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino\}-2-methylbutanenitrile +
0
cyanazine +
10