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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:butamben
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Accession:CHEBI:3231 term browser browse the term
Definition:An amino acid ester resulting from the formal condensation of the carboxy group of 4-aminobenzoic acid with the hydroxy group of butan-1-ol. Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders.
Synonyms:exact_synonym: butyl 4-aminobenzoate
 related_synonym: 4-(butoxycarbonyl)aniline;   4-aminobenzoic acid butyl ester;   BAB;   Butesin;   Butoform;   Formula=C11H15NO2;   InChI=1S/C11H15NO2/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7H,2-3,8,12H2,1H3;   InChIKey=IUWVALYLNVXWKX-UHFFFAOYSA-N;   Planoform;   SMILES=CCCCOC(=O)c1ccc(N)cc1;   Scuroform;   Scuroforme;   butyl aminobenzoate;   butyl p-aminobenzoate;   n-butyl p-aminobenzoate;   p-aminobenzoic acid butyl ester
 xref: CAS:94-25-7;   Drug_Central:3051;   KEGG:C07875;   KEGG:D00730;   LINCS:LSM-5413
 xref_mesh: MESH:C004605
 xref: PMID:15920194;   PMID:15923341;   PMID:16368819;   PMID:18499609;   PMID:22133806;   PMID:2393134;   PMID:24486399;   PMID:7793660;   PMID:9009953;   PMID:9690593;   Patent:GB252870;   Patent:US1440652;   Reaxys:1211465;   Wikipedia:Butamben
 cyclic_relationship: is_conjugate_base_of CHEBI:86302


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butamben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP butamben binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to MED1 protein]; butamben promotes the reaction [NR1I2.S protein binds to MED1 protein] CTD PMID:12198127 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA1 protein]; butamben promotes the reaction [NR1I2.S protein binds to NCOA1 protein] CTD PMID:12198127 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA2 protein] CTD PMID:12198127 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA3 protein] CTD PMID:12198127 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        aetiopathogenetic role 19166
          allergen 17646
            4-aminobenzoic acid 31
              butamben 5
                butamben picrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      monocarboxylic acid 17984
                                        fatty acid 16792
                                          fatty acid derivative 8960
                                            fatty alcohol 6103
                                              primary fatty alcohol 5765
                                                short-chain primary fatty alcohol 5756
                                                  butan-1-ol 5722
                                                    butamben 5
                                                      butamben picrate 0
paths to the root