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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-Hydroxybenzyl isothiocyanate
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Accession:CHEBI:178135 term browser browse the term
Synonyms:exact_synonym: 4-(isothiocyanatomethyl)phenol
 related_synonym: Formula=C8H7NOS;   InChI=1S/C8H7NOS/c10-8-3-1-7(2-4-8)5-9-6-11/h1-4,10H,5H2;   InChIKey=ATKWJXUJUNLTFU-UHFFFAOYSA-N;   SMILES=S=C=NCC1=CC=C(O)C=C1
 xref: CAS:2086-86-4;   Chemspider:141134;   HMDB:HMDB0032580
 xref_mesh: MESH:C031364


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4-Hydroxybenzyl isothiocyanate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP 4-hydroxybenzyl isothiocyanate results in increased activity of CAT protein CTD PMID:22664424 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions		 EXP 4-hydroxybenzyl isothiocyanate results in increased expression of CYP1A1 mRNA
4-hydroxybenzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]		 CTD PMID:22664424 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression		 EXP 4-hydroxybenzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]
4-hydroxybenzyl isothiocyanate results in increased expression of CYP1A2 mRNA		 CTD PMID:22664424 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
decreases expression		 EXP 4-hydroxybenzyl isothiocyanate results in decreased activity of CYP3A2 protein
4-hydroxybenzyl isothiocyanate results in decreased expression of CYP3A2 mRNA		 CTD PMID:22664424 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
increases activity		 EXP 4-hydroxybenzyl isothiocyanate results in increased expression of HMOX1 mRNA; 4-hydroxybenzyl isothiocyanate results in increased expression of HMOX1 protein
4-hydroxybenzyl isothiocyanate results in increased activity of HMOX1 protein		 CTD PMID:22664424 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression EXP 4-hydroxybenzyl isothiocyanate results in increased expression of NFE2L2 protein CTD PMID:22664424 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
increases activity		 EXP 4-hydroxybenzyl isothiocyanate results in increased expression of NQO1 mRNA
4-hydroxybenzyl isothiocyanate results in increased activity of NQO1 protein		 CTD PMID:22664424 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      molecular entity 19806
        polyatomic entity 19764
          heteroatomic molecular entity 19720
            hydroxides 19299
              organic hydroxy compound 18923
                phenols 18605
                  4-Hydroxybenzyl isothiocyanate 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic aromatic compound 19336
                                  phenols 18605
                                    4-Hydroxybenzyl isothiocyanate 7
paths to the root