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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ganoderol B
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Accession:CHEBI:142261 term browser browse the term
Definition:A tetracyclic triterpenoid that is lanosta-7,9(11),24-triene which is substituted by hydroxy groups at positions 3 and 27. It has been isolated from several Ganoderma species.
Synonyms:exact_synonym: (3beta,24E)-lanosta-7,9(11),24-triene-3,26-diol
 related_synonym: Formula=C30H48O2;   InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=AOXXVRDKZLRGTJ-AZIDVCJLSA-N;   SMILES=C1([C@]2([C@](CC[C@@H]1O)(C=3C(=CC2)[C@]4([C@@](CC3)(C)[C@](CC4)([C@@H](CC/C=C(/CO)\\C)C)[H])C)C)[H])(C)C;   ganodermadiol
 xref: CAS:104700-96-1;   FooDB:FDB013983;   HMDB:HMDB0035314;   KNApSAcK:C00023868
 xref_mesh: MESH:C521787
 xref: PMID:11908995;   PMID:12628419;   PMID:17313101;   PMID:17499997;   PMID:21596546;   PMID:23790868;   PMID:28875673;   PMID:28912878;   PMID:29748985


show annotations for term's descendants           Sort by:
ganoderol B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO ganoderol B binds to and results in decreased activity of AR protein; ganoderol B inhibits the reaction [Dihydrotestosterone binds to AR protein] CTD PMID:17499997 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO ganoderol B results in decreased expression of KLK3 mRNA CTD PMID:17499997 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity EXP ganoderol B results in decreased activity of SRD5A1 protein CTD PMID:17499997 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        antimicrobial agent 18166
          antiviral agent 11074
            ganoderol B 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic polycyclic compound 17247
                                  steroid 14693
                                    hydroxy steroid 14439
                                      3-hydroxy steroid 12775
                                        sterol 463
                                          3beta-sterol 457
                                            ganoderol B 3
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