CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: amitriptylinoxide
Accession: CHEBI:135224
browse the term
Synonyms: related_synonym: Formula=C20H23NO; InChI=1S/C20H23NO/c1-21(2,22)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3; InChIKey=ZPMKQFOGINQDAM-UHFFFAOYSA-N; SMILES=C(CC[N+](C)(C)[O-])=C1C=2C(CCC3=C1C=CC=C3)=CC=CC2; amitriptyline N-oxide; amitriptyline oxide
xref: CAS:4317-14-0; Drug_Central:181
xref_mesh: MESH:C006566
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases abundance
ISO
CYP1A2 protein results in increased abundance of amitriptyline N-oxide
CTD
PMID:27320963
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases abundance
ISO
CYP2B6 protein results in increased abundance of amitriptyline N-oxide
CTD
PMID:27320963
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
increases abundance
ISO
CYP2C19 protein results in increased abundance of amitriptyline N-oxide
CTD
PMID:27320963
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
increases abundance
ISO
CYP2D6 protein results in increased abundance of amitriptyline N-oxide
CTD
PMID:27320963
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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Fmo3
flavin containing dimethylaniline monoxygenase 3
increases abundance
ISO
FMO3 protein results in increased abundance of amitriptyline N-oxide
CTD
PMID:27320963
NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
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