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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:amitriptylinoxide
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Accession:CHEBI:135224 term browser browse the term
Synonyms:related_synonym: Formula=C20H23NO;   InChI=1S/C20H23NO/c1-21(2,22)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3;   InChIKey=ZPMKQFOGINQDAM-UHFFFAOYSA-N;   SMILES=C(CC[N+](C)(C)[O-])=C1C=2C(CCC3=C1C=CC=C3)=CC=CC2;   amitriptyline N-oxide;   amitriptyline oxide
 xref: CAS:4317-14-0;   Drug_Central:181
 xref_mesh: MESH:C006566



show annotations for term's descendants           Sort by:
amitriptylinoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases abundance ISO CYP1A2 protein results in increased abundance of amitriptyline N-oxide CTD PMID:27320963 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases abundance ISO CYP2B6 protein results in increased abundance of amitriptyline N-oxide CTD PMID:27320963 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases abundance ISO CYP2C19 protein results in increased abundance of amitriptyline N-oxide CTD PMID:27320963 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases abundance ISO CYP2D6 protein results in increased abundance of amitriptyline N-oxide CTD PMID:27320963 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases abundance ISO FMO3 protein results in increased abundance of amitriptyline N-oxide CTD PMID:27320963 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19839
      group 19798
        polyatomic entity 19797
          molecule 19701
            cyclic compound 19516
              organic cyclic compound 19498
                organic polycyclic compound 17247
                  organic tricyclic compound 15688
                    amitriptylinoxide 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      p-block molecular entity 19789
                        carbon group molecular entity 19737
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic polycyclic compound 17247
                                  organic tricyclic compound 15688
                                    amitriptylinoxide 5
paths to the root