The PhysGen Knockout program (“Mechanistic Characterization of Genes for Hypertension and Renal Disease”) aimed to knock out a large number of genes nominated by genome wide association studies, combine these gene knockouts (KO) with hypertensive and normotensive strains, and phenotypically characterize them.
The scientific community was asked to nominate genes involved in the development of hypertension and renal disease. If interested in obtaining any of these strains, please contact Mindy Dwinell, Ph.D. (mrdwinel@mcw.edu). |
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