Tlr7, 8, 9 ligands

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Tlr7, 8, 9 ligands

These receptors are localized to endosomes and other intracellular vesicles and respond to nucleic acids.The ligands for Tlr7, 8 and 9 are listed:

Tlr7 – single stranded RNA from viruses or endogenous sources, specific RNA sequences
Tlr8 – single stranded RNA from viruses or endogenous sources, specific RNA sequences
Tlr9 – DNA containing unmethylated CpG motifs, a common type of bacterial DNA

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.