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Phenotypes – Blood Pressure

PGA Blood Pressure Data

PhysGen Program for Genomic Application is funded by NHLBI to develop consomic and knockout rat strains, phenotypically characterize these strains, and provide these resources to the scientific community. 

     Left ventricular systolic pressure (Cardiac protocol) [download data]
     Mean arterial blood pressure (Renal Protocol, high salt) [download data]
     Mean arterial blood pressure (Respiratory protocol, low salt) [download data]


 

Mean arterial blood pressure (mmHg)

MALES

Low salt (0.4%)

High salt (4%)

LS (depleted)

Mean

SEM

Mean

SEM

Mean

SEM

BN

118.7

4.1

101.9

2.0

95.3

4.4

CDF

112.3

2.4

117.3

1.3

111.8

2.1

CD@IGS

120.6

1.7

113.2

1.9

108.6

3.8

FHH

130.6

2.3

134.0

2.1

132.8

3.5

GH

171.6

4.5

175.9

4.8

163.8

6.0

LE/BluGill

109.9

3.1

LEW

104.5

3.5

103.9

3.0

96.1

2.3

SHR

154.6

3.6

163.2

4.0

140.0

4.9

SD/Hsd

116.2

5.0

116.2

1.6

114.4

2.0

SS

126.1

1.4

147.9

3.4

131.5

2.9

WKY

121.4

5.0

118.7

1.1

103.9

5.5

 

             

 

Mean arterial blood pressure (mmHg)

FEMALES

Low salt (0.4%)

High salt (4%)

LS (depleted)

Mean

SEM

Mean

SEM

Mean

SEM

BN

112.3

3.6

101.8

1.5

94.4

4.1

CDF

115.1

6.6

115.8

2.1

109.8

2.6

CD@IGS

110.7

6.2

107.2

2.6

101.2

3.3

FHH

129.3

3.6

131.5

2.6

126.5

3.0

GH

158.6

5.2

166.9

4.2

155.7

5.8

LE/BluGill

103.5

6.9

LEW

112.7

2.6

105.7

2.3

97.5

1.7

SHR

145.2

3.9

145.8

2.7

127.0

4.1

SD/Hsd

116.5

5.7

111.0

1.2

108.6

1.9

SS

127.4

2.0

148.5

3.8

130.9

4.1

WKY

120.3

4.4

115.7

1.6

114.0

3.8

 

NBRP Blood Pressure Data

The NBRP is a rat repository founded by the the Ministry of Education, Culture, Sports, Science and Technology (Monkasho) in Japan.  The NBRP-Rat collects, preserves and supplies rat strains and maintains a public database with charcterization of phenotypes and genetic profiles. 

     NBRP systolic blood pressure     

Methods & Details

Phenotyping methods and details

 


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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.