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Phenotypes – Myocardial Ischemia

PGA Myocardial Ischemia Data

The PhysGen Program for Genomic Application was funded by NHLBI to develop consomic and knockout rat strains, phenotypically characterize these strains, and provide these resources to the scientific community. The data generated by the PGA studies has been deposited into the RGD Phenominer Database. 

 

Post-ischemic infarct size

% left ventricle

MALES

Normoxia

Chronic Hypoxia

Mean

SEM

Mean

SEM

BN

3.1

0.9

6.3

2.0

CDF

12.9

6.6

7.5

1.5

CD@IGS

15.0

4.8

9.4

4.4

FHH

10.9

1.6

7.9

0.9

GH

13.1

3.3

9.1

3.7

LE/BluGill

10.7

2.9

17.5

7.3

LEW

22.7

4.2

16.5

3.8

SHR

17.3

2.6

27.3

4.5

SD/Hsd

25.7

3.2

16.1

2.7

SS

27.0

1.7

20.2

1.5

WKY

9.0

3.0

19.5

9.7

 

                  

 

Post-ischemic infarct size

% left ventricle

FEMALES

Normoxia

Chronic Hypoxia

Mean

SEM

Mean

SEM

BN

2.3

0.7

4.3

1.1

CDF

5.9

2.5

12.8

5.1

CD@IGS

7.2

4.6

6.6

3.6

FHH

11.8

2.7

10.1

2.2

GH

17.5

4.0

7.9

2.0

LE/BluGill

12.1

3.5

7.4

3.8

LEW

20.7

7.3

9.0

2.2

SHR

14.2

2.6

23.2

3.4

SD/Hsd

16.4

2.7

17.7

2.9

SS

21.5

1.8

23.5

4.5

WKY

9.7

3.0

19.1

8.8

 

NBRP Myocardial Ischemia Data

The NBRP is a rat repository founded by the the Ministry of Education, Culture, Sports, Science and Technology (Monkasho) in Japan.  The NBRP-Rat collects, preserves and supplies rat strains and maintains a public database with charcterization of phenotypes and genetic profiles. 

     No myocardial ischemia data available.     

Methods & Details

Phenotyping protocols

 

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.