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Strain Registration

Strain: LER/N

Symbol: LER/N
Strain: LER
Substrain: N
RGD ID: 68071
Citation ID: RRID:RRRC_00164
Ontology ID: RS:0000455
Type: inbred
Available Source: Not Available
Description: Originally designated Le-R and thought to be a mutation within LEW conferring resistance of experimental allergic encephalomyelitis (EAE) (Waxman et al, 1981, Driscoll et al 1985, Gasser et al, 1983). However, it now appears to have been an accidental genetic contamination by BUF/N rats (Goldmuntz et al, 1993),. See LEW, Immunology.
Genetic Markers: c
Coat Color: Albino.
Inbred Generations: F30 (NIH 1989)
Last Known Status: Extinct






References

References - curated
# Reference Title Reference Citation
1. Inbred Strains Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
2. Rat Strain List M. Festing Rat Strain List
3. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Resistant to the induction of EAE, though susceptible to adoptively transferred EAE when theyare injected with encephalitogenic T cells from EAE-susceptible LEW rats (Blankenhorn et al,1995). 1004
strain_characteristics Resistant to the induction of EAE, though susceptible to adoptively transferred EAE when theyare injected with encephalitogenic T cells from EAE-susceptible LEW rats (Blankenhorn et al,1995). 634612

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-03 LER/N    LER/N    Name updated 68913 APPROVED
2015-04-03 LER/N    LER/N    Name updated 68913 APPROVED
2013-04-15 LER/N    LER/N    Name updated 68913 APPROVED
2013-04-15 LER/N    LER/N    Name updated 68913 APPROVED
2012-04-18 LER/N    LER/N    Name updated 68913 APPROVED
2012-04-18 LER/N    LER/N    Name updated 68913 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00164 RGD