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ONTOLOGY REPORT - ANNOTATIONS

Term:obsolete protein kinase A signaling
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Accession:GO:0010737 term browser browse the term
Status:
This term is obsolete. We suggest searching for the text of the ontology term or for a keyword rather than searching for the ontology ID. For more information, please contact us.
Definition:OBSOLETE. An intracellular signaling cassette that starts with the activation of protein kinase A (PKA), and ends with the regulation of a downstream cellular process, e.g. transcription. The PKA catalytic subunit (PKA-C) is normally present in a complex with its regulatory subunit, PKA-R. The inhibitory action of PKA-R is released upon cAMP binding, which results in the activation of PKA-C.
Comment:This term was obsoleted because it does not represent a specific pathway. Consider cAMP/PKA signal transduction ; GO:0141156 or adenylate cyclase-activating G protein-coupled receptor signaling pathway ; GO:0007189.
Synonyms:exact_synonym: protein kinase A signal transduction
 related_synonym: PKA signaling cascade;   protein kinase A signaling cascade;   protein kinase A signalling cascade
 xref: Reactome:R-HSA-163358 "PKA-mediated phosphorylation of key metabolic factors"
 consider: GO:0007189;   GO:0141156


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