Hras Variant Search Result - Rat Genome Database

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673 records found for search term Hras

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RGD ID	Symbol	Variant Type	Name	Trait	Clinical Significance	Chr	Start	Stop	Species	Annotations	Match
126746061	CV1015371	single nucleotide variant	NM_005343.4(HRAS):c.-2C>A	not specified [RCV001328343]	uncertain significance	11	534324	534324	Human		name
8691300	CV141260	single nucleotide variant	NM_005343.4(HRAS):c.*1C>T	HRAS-related disorder [RCV003894980]\|not provided [RCV000588758]\|not specified [RCV000125382]	benign\|likely benign	11	532635	532635	Human		name , trait , alternate_id
38598423	CV963282	single nucleotide variant	NM_005343.4(HRAS):c.-5G>A	not specified [RCV001251409]	uncertain significance	11	534327	534327	Human		name
150335764	CV1172267	single nucleotide variant	NM_005343.4(HRAS):c.*76G>C	not provided [RCV001540698]	likely benign	11	532452	532452	Human		name
150473467	CV1217633	single nucleotide variant	NM_005343.4(HRAS):c.-33G>A	not provided [RCV001615644]	benign	11	534355	534355	Human		name
8691299	CV141259	single nucleotide variant	NM_005343.4(HRAS):c.-10C>T	Costello syndrome [RCV002512524]\|Noonan syndrome and Noonan-related syndrome [RCV001813385]\|not provided [RCV000509255]\|not specified [RCV000154268]	benign\|not provided	11	534332	534332	Human	3	name
8691299	CV141259	single nucleotide variant	NM_005343.4(HRAS):c.-10C>T	Costello syndrome [RCV002512524]\|Noonan syndrome and Noonan-related syndrome [RCV001813385]\|not provided [RCV000509255]\|not specified [RCV000154268]	benign\|not provided	11	534332	534333	Human	3	name
405654892	CV3228370	single nucleotide variant	NM_005343.4(HRAS):c.-17C>T	not specified [RCV003995105]	benign	11	534339	534339	Human		name
13797394	CV552664	single nucleotide variant	NM_005343.4(HRAS):c.-19C>T	not provided [RCV000681168]	likely benign	11	534341	534341	Human		name
150474726	CV1217844	single nucleotide variant	NM_005343.4(HRAS):c.-101C>T	Noonan syndrome and Noonan-related syndrome [RCV001813603]\|not provided [RCV001615855]	benign\|uncertain significance	11	535463	535463	Human		name
598122695	CV3884627	single nucleotide variant	NM_005343.4(HRAS):c.*5+4A>T	not specified [RCV005237319]	uncertain significance	11	532627	532627	Human		name
9832734	CV48920	single nucleotide variant	NM_005343.4(HRAS):c.*6-2A>C	not specified [RCV000157910]	likely benign	11	532524	532524	Human		name
127251883	CV1078344	single nucleotide variant	NM_005343.4(HRAS):c.112-6C>T	Costello syndrome [RCV001400227]	likely benign	11	533950	533950	Human	1	name
127325089	CV1142410	deletion	NM_005343.4(HRAS):c.291-9del	Costello syndrome [RCV001505890]\|HRAS-related disorder [RCV003948481]	likely benign	11	533621	533621	Human	1	name , trait , alternate_id
150462616	CV1234938	single nucleotide variant	NM_005343.4(HRAS):c.*5+29C>T	not provided [RCV001649520]	benign	11	532602	532602	Human		name
150504609	CV1240788	single nucleotide variant	NM_005343.4(HRAS):c.*5+24C>T	not provided [RCV001657631]	benign	11	532607	532607	Human		name
150451692	CV1260291	single nucleotide variant	NM_005343.4(HRAS):c.*5+35C>T	not provided [RCV001680781]	benign	11	532596	532596	Human		name
8691301	CV141261	single nucleotide variant	NM_005343.4(HRAS):c.*5+14C>A	not specified [RCV000125383]	benign	11	532617	532617	Human		name
152122046	CV1547690	single nucleotide variant	NM_005343.4(HRAS):c.451-6T>C	Costello syndrome [RCV002081687]	likely benign	11	532761	532761	Human	1	name
152147049	CV1608094	single nucleotide variant	NM_005343.4(HRAS):c.111+8T>C	Costello syndrome [RCV002178880]	likely benign	11	534204	534204	Human	1	name
152142270	CV1629083	single nucleotide variant	NM_005343.4(HRAS):c.112-9C>T	Costello syndrome [RCV002100938]	likely benign	11	533953	533953	Human	1	name
152159967	CV1649968	single nucleotide variant	NM_005343.4(HRAS):c.451-9C>T	Costello syndrome [RCV002159464]	likely benign	11	532764	532764	Human	1	name
155676040	CV1854361	single nucleotide variant	NM_005343.4(HRAS):c.290+3G>T	Cardiovascular phenotype [RCV002438068]\|Costello syndrome [RCV003102855]	uncertain significance	11	533763	533763	Human	1	name
156046443	CV1887503	single nucleotide variant	NM_005343.4(HRAS):c.450+7C>T	Costello syndrome [RCV003078717]	likely benign\|uncertain significance	11	533446	533446	Human	1	name
156316703	CV1901273	single nucleotide variant	NM_005343.4(HRAS):c.450+9G>A	Costello syndrome [RCV002578989]	likely benign	11	533444	533444	Human	1	name
156016331	CV1993285	single nucleotide variant	NM_005343.4(HRAS):c.290+7C>T	Costello syndrome [RCV002636482]	likely benign	11	533759	533759	Human	1	name
156293414	CV2152727	single nucleotide variant	NM_005343.4(HRAS):c.451-4C>G	Costello syndrome [RCV003010060]	likely benign	11	532759	532759	Human	1	name
11347570	CV241156	single nucleotide variant	NM_005343.4(HRAS):c.290+6C>A	Costello syndrome [RCV000232587]	uncertain significance	11	533760	533760	Human	1	name
11348575	CV241158	single nucleotide variant	NM_005343.4(HRAS):c.111+6C>T	Cardiovascular phenotype [RCV004020817]\|Costello syndrome [RCV000227164]	uncertain significance	11	534206	534206	Human	1	name
401723858	CV2737895	single nucleotide variant	NM_005343.4(HRAS):c.-53-5G>A	not provided [RCV003315067]	uncertain significance	11	534380	534380	Human		name
401940292	CV2832651	single nucleotide variant	NM_005343.4(HRAS):c.-54+3G>A	Costello syndrome [RCV003448632]	uncertain significance	11	535413	535413	Human	1	name
405024673	CV2890509	single nucleotide variant	NM_005343.4(HRAS):c.290+3G>A	Costello syndrome [RCV003516258]	uncertain significance	11	533763	533763	Human	1	name
405012956	CV2910151	single nucleotide variant	NM_005343.4(HRAS):c.291-5C>G	Costello syndrome [RCV003515141]	likely benign	11	533617	533617	Human	1	name
402501104	CV2995985	single nucleotide variant	NM_005343.4(HRAS):c.290+7C>G	Costello syndrome [RCV003628317]	likely benign	11	533759	533759	Human	1	name
404977736	CV3127260	single nucleotide variant	NM_005343.4(HRAS):c.450+4A>C	Costello syndrome [RCV003825484]	uncertain significance	11	533449	533449	Human	1	name
408375998	CV3505460	single nucleotide variant	NM_005343.4(HRAS):c.112-9C>G	Costello syndrome [RCV005103651]\|HRAS-related disorder [RCV004726495]	likely benign	11	533953	533953	Human	1	name , trait , alternate_id
12846482	CV371481	single nucleotide variant	NM_005343.4(HRAS):c.*5+20C>T	not provided [RCV004718629]\|not specified [RCV000441723]	benign	11	532611	532611	Human		name
12841911	CV374139	single nucleotide variant	NM_005343.4(HRAS):c.291-8C>T	Costello syndrome [RCV001084880]\|not provided [RCV000433431]	likely benign	11	533620	533620	Human	1	name
597845472	CV3765483	deletion	NM_005343.4(HRAS):c.450+6del	Costello syndrome [RCV005121127]	uncertain significance	11	533447	533447	Human	1	name
597862705	CV3795711	single nucleotide variant	NM_005343.4(HRAS):c.291-7C>G	Costello syndrome [RCV005136721]	likely benign	11	533619	533619	Human	1	name
597905535	CV3836030	single nucleotide variant	NM_005343.4(HRAS):c.111+3G>A	Costello syndrome [RCV005179803]	uncertain significance	11	534209	534209	Human	1	name
12891199	CV398664	single nucleotide variant	NM_005343.4(HRAS):c.451-5C>G	Costello syndrome [RCV001078758]\|not provided [RCV000681281]	likely benign\|conflicting interpretations of pathogenicity\|uncertain significance	11	532760	532760	Human	1	name
617152962	CV4018516	single nucleotide variant	NM_005343.4(HRAS):c.*5+11C>A	not specified [RCV005418777]	uncertain significance	11	532620	532620	Human		name
13479635	CV442535	single nucleotide variant	NM_005343.4(HRAS):c.291-6T>G	Costello syndrome [RCV000872282]\|HRAS-related disorder [RCV003962443]\|Hereditary cancer-predisposing syndrome [RCV002257777]\|Large congenital melanocytic nevus [RCV002497006]\|RASopathy [RCV000521008]\|not specified [RCV001255585]	benign\|likely benign	11	533618	533618	Human	16	name , trait , alternate_id
13470429	CV461205	single nucleotide variant	NM_005343.4(HRAS):c.290+9C>T	Costello syndrome [RCV001425103]	likely benign	11	533757	533757	Human	1	name
150485741	CV48919	single nucleotide variant	NM_005343.4(HRAS):c.*6-48G>A	not provided [RCV001715658]	benign	11	532570	532570	Human		name
13536590	CV503299	single nucleotide variant	NM_005343.4(HRAS):c.-54+7G>A	not specified [RCV000609219]	likely benign	11	535409	535409	Human		name
13527898	CV503676	single nucleotide variant	NM_005343.4(HRAS):c.451-5C>T	Cardiovascular phenotype [RCV004024985]\|Costello syndrome [RCV000637310]\|not provided [RCV001698422]	likely benign\|uncertain significance	11	532760	532760	Human	1	name
13797922	CV552658	single nucleotide variant	NM_005343.4(HRAS):c.*5+14C>G	not provided [RCV000680622]	likely benign	11	532617	532617	Human		name
14691366	CV621820	single nucleotide variant	NM_005343.4(HRAS):c.291-9A>G	Costello syndrome [RCV000864531]\|not specified [RCV000781471]	likely benign\|uncertain significance	11	533621	533621	Human	1	name
14706248	CV652212	single nucleotide variant	NM_005343.4(HRAS):c.451-3C>T	Costello syndrome [RCV000803345]\|not specified [RCV005407973]	uncertain significance	11	532758	532758	Human	1	name
14705936	CV652331	single nucleotide variant	NM_005343.4(HRAS):c.290+9C>G	Costello syndrome [RCV000802561]	uncertain significance	11	533757	533757	Human	1	name
14702869	CV653976	single nucleotide variant	NM_005343.4(HRAS):c.451-4C>T	Costello syndrome [RCV000874555]\|Noonan syndrome [RCV000824933]	likely benign	11	532759	532759	Human	2	name
15137589	CV695528	single nucleotide variant	NM_005343.4(HRAS):c.451-8T>C	Costello syndrome [RCV000877025]	likely benign	11	532763	532763	Human	1	name
15176688	CV775696	single nucleotide variant	NM_005343.4(HRAS):c.111+7C>T	Costello syndrome [RCV001463156]	likely benign	11	534205	534205	Human	1	name
15174039	CV775857	single nucleotide variant	NM_005343.4(HRAS):c.112-4G>A	Costello syndrome [RCV001416693]\|not specified [RCV001797803]	likely benign\|uncertain significance	11	533948	533948	Human	1	name
15107782	CV779544	single nucleotide variant	NM_005343.4(HRAS):c.112-7C>T	Costello syndrome [RCV002066363]	likely benign	11	533951	533951	Human	1	name
34896626	CV917489	single nucleotide variant	NM_005343.4(HRAS):c.290+1G>C	not specified [RCV001194130]	uncertain significance	11	533765	533765	Human		name
38457167	CV959992	single nucleotide variant	NM_005343.4(HRAS):c.451-6T>G	Costello syndrome [RCV001228584]	likely benign\|uncertain significance	11	532761	532761	Human	1	name
126740336	CV994568	single nucleotide variant	NM_005343.4(HRAS):c.291-3C>T	Costello syndrome [RCV001305262]\|Hereditary cancer-predisposing syndrome [RCV002258190]	uncertain significance	11	533615	533615	Human	2	name
127266782	CV1100059	single nucleotide variant	NM_005343.4(HRAS):c.291-10C>T	Costello syndrome [RCV001440352]	likely benign	11	533622	533622	Human	1	name
150340433	CV1168241	single nucleotide variant	NM_005343.4(HRAS):c.291-30C>T	not provided [RCV001535365]	benign	11	533642	533642	Human		name
150509306	CV1214267	single nucleotide variant	NM_005343.4(HRAS):c.450+38C>T	not provided [RCV001596788]	benign	11	533415	533415	Human		name
150462240	CV1234883	single nucleotide variant	NM_005343.4(HRAS):c.-54+47C>T	not provided [RCV001649465]	benign	11	535369	535369	Human		name
150500480	CV1256106	single nucleotide variant	NM_005343.4(HRAS):c.450+49G>A	not provided [RCV001676730]	benign	11	533404	533404	Human		name
151817366	CV1337424	single nucleotide variant	NM_005343.4(HRAS):c.112-13T>C	Costello syndrome [RCV001919222]	likely benign	11	533957	533957	Human	1	name
151856966	CV1401962	single nucleotide variant	NM_005343.4(HRAS):c.111+11C>T	Costello syndrome [RCV002017298]	likely benign\|uncertain significance	11	534201	534201	Human	1	name
151837109	CV1416846	single nucleotide variant	NM_005343.4(HRAS):c.112-10C>A	Costello syndrome [RCV002014909]	likely benign\|uncertain significance	11	533954	533954	Human	1	name
152117932	CV1522228	single nucleotide variant	NM_005343.4(HRAS):c.451-17C>T	Costello syndrome [RCV002081150]	likely benign	11	532772	532772	Human	1	name
152159429	CV1522637	single nucleotide variant	NM_005343.4(HRAS):c.112-19G>C	Costello syndrome [RCV002140662]	likely benign	11	533963	533963	Human	1	name
152057790	CV1523246	single nucleotide variant	NM_005343.4(HRAS):c.291-16G>C	Costello syndrome [RCV002167655]	likely benign	11	533628	533628	Human	1	name
152152420	CV1529506	single nucleotide variant	NM_005343.4(HRAS):c.111+17C>T	Costello syndrome [RCV002202177]	likely benign	11	534195	534195	Human	1	name
152126997	CV1530216	duplication	NM_005343.4(HRAS):c.112-20dup	Costello syndrome [RCV002198809]	likely benign	11	533963	533964	Human	1	name
152110065	CV1536917	single nucleotide variant	NM_005343.4(HRAS):c.451-14C>T	Costello syndrome [RCV002215359]	likely benign	11	532769	532769	Human	1	name
152116512	CV1540987	single nucleotide variant	NM_005343.4(HRAS):c.112-19G>A	Costello syndrome [RCV002197464]	likely benign	11	533963	533963	Human	1	name
152149288	CV1545362	single nucleotide variant	NM_005343.4(HRAS):c.451-15T>C	Costello syndrome [RCV002121516]	likely benign	11	532770	532770	Human	1	name
152075738	CV1551258	single nucleotide variant	NM_005343.4(HRAS):c.112-14C>T	Costello syndrome [RCV002192380]	likely benign	11	533958	533958	Human	1	name
152123703	CV1570622	single nucleotide variant	NM_005343.4(HRAS):c.451-12C>T	Costello syndrome [RCV002217118]	likely benign	11	532767	532767	Human	1	name
152033988	CV1573184	single nucleotide variant	NM_005343.4(HRAS):c.290+14G>A	Costello syndrome [RCV002187185]	likely benign	11	533752	533752	Human	1	name
152053995	CV1575120	single nucleotide variant	NM_005343.4(HRAS):c.111+18G>A	Costello syndrome [RCV002109318]	likely benign	11	534194	534194	Human	1	name
152113149	CV1586634	single nucleotide variant	NM_005343.4(HRAS):c.450+20C>G	Costello syndrome [RCV002197051]	likely benign	11	533433	533433	Human	1	name
152026978	CV1593726	single nucleotide variant	NM_005343.4(HRAS):c.291-13T>G	Costello syndrome [RCV002104738]	likely benign	11	533625	533625	Human	1	name
152176427	CV1594208	single nucleotide variant	NM_005343.4(HRAS):c.291-18T>C	Costello syndrome [RCV002164572]	likely benign	11	533630	533630	Human	1	name
152082086	CV1607942	single nucleotide variant	NM_005343.4(HRAS):c.451-13C>A	Costello syndrome [RCV002193154]	likely benign	11	532768	532768	Human	1	name
152087997	CV1614720	single nucleotide variant	NM_005343.4(HRAS):c.291-15C>T	Costello syndrome [RCV002093772]	likely benign	11	533627	533627	Human	1	name
152043208	CV1624367	single nucleotide variant	NM_005343.4(HRAS):c.451-13C>T	Costello syndrome [RCV002126356]	likely benign	11	532768	532768	Human	1	name
152141917	CV1629020	single nucleotide variant	NM_005343.4(HRAS):c.450+15C>T	Costello syndrome [RCV002100893]	likely benign	11	533438	533438	Human	1	name
152115569	CV1640023	single nucleotide variant	NM_005343.4(HRAS):c.291-17C>T	Costello syndrome [RCV002080842]	likely benign	11	533629	533629	Human	1	name
152123450	CV1641126	single nucleotide variant	NM_005343.4(HRAS):c.450+13T>C	Costello syndrome [RCV002098481]	likely benign	11	533440	533440	Human	1	name
152101804	CV1645911	single nucleotide variant	NM_005343.4(HRAS):c.450+16A>G	Costello syndrome [RCV002173201]	likely benign	11	533437	533437	Human	1	name
152038875	CV1647858	single nucleotide variant	NM_005343.4(HRAS):c.291-16G>A	Costello syndrome [RCV002087656]	likely benign	11	533628	533628	Human	1	name
152115513	CV1654081	single nucleotide variant	NM_005343.4(HRAS):c.112-12G>A	Costello syndrome [RCV002097425]	likely benign	11	533956	533956	Human	1	name
152124380	CV1665670	single nucleotide variant	NM_005343.4(HRAS):c.290+10G>C	Costello syndrome [RCV002198483]	likely benign	11	533756	533756	Human	1	name
152125316	CV1665783	single nucleotide variant	NM_005343.4(HRAS):c.291-15C>A	Costello syndrome [RCV002198596]	likely benign	11	533627	533627	Human	1	name
9690632	CV174802	single nucleotide variant	NM_005343.4(HRAS):c.450+84C>A	not specified [RCV000156318]	uncertain significance	11	533369	533369	Human		name
9691714	CV175215	single nucleotide variant	NM_005343.4(HRAS):c.112-10C>T	Costello syndrome [RCV000637313]\|not specified [RCV000150833]	likely benign	11	533954	533954	Human	1	name
156405714	CV1884567	single nucleotide variant	NM_005343.4(HRAS):c.112-14C>G	Costello syndrome [RCV003070110]	likely benign	11	533958	533958	Human	1	name
156046674	CV1887518	single nucleotide variant	NM_005343.4(HRAS):c.451-19C>T	Costello syndrome [RCV003078725]	likely benign	11	532774	532774	Human	1	name
156411107	CV1892920	single nucleotide variant	NM_005343.4(HRAS):c.112-11T>A	Costello syndrome [RCV003072336]	uncertain significance	11	533955	533955	Human	1	name
156330206	CV1954038	single nucleotide variant	NM_005343.4(HRAS):c.450+20C>T	Costello syndrome [RCV002579954]	likely benign	11	533433	533433	Human	1	name
156035025	CV2002596	single nucleotide variant	NM_005343.4(HRAS):c.450+14C>T	Costello syndrome [RCV002658816]	likely benign	11	533439	533439	Human	1	name
156274898	CV2014890	single nucleotide variant	NM_005343.4(HRAS):c.450+18C>A	Costello syndrome [RCV002715106]	likely benign	11	533435	533435	Human	1	name
156074101	CV2029213	single nucleotide variant	NM_005343.4(HRAS):c.290+19G>C	Costello syndrome [RCV002760412]	likely benign	11	533747	533747	Human	1	name
156315560	CV2086013	single nucleotide variant	NM_005343.4(HRAS):c.451-20T>G	Costello syndrome [RCV002898970]	likely benign	11	532775	532775	Human	1	name
156026702	CV2139217	single nucleotide variant	NM_005343.4(HRAS):c.112-17G>T	Costello syndrome [RCV002998955]	likely benign	11	533961	533961	Human	1	name
155964988	CV2155923	single nucleotide variant	NM_005343.4(HRAS):c.112-18A>T	Costello syndrome [RCV003015653]	likely benign	11	533962	533962	Human	1	name
156351689	CV2190347	single nucleotide variant	NM_005343.4(HRAS):c.111+12G>A	Costello syndrome [RCV003048383]	likely benign	11	534200	534200	Human	1	name
405016332	CV2856476	single nucleotide variant	NM_005343.4(HRAS):c.451-16A>G	Costello syndrome [RCV003515472]	likely benign	11	532771	532771	Human	1	name
405015602	CV2859078	single nucleotide variant	NM_005343.4(HRAS):c.290+16C>T	Costello syndrome [RCV003515370]	likely benign	11	533750	533750	Human	1	name
405004453	CV2889088	single nucleotide variant	NM_005343.4(HRAS):c.290+15G>A	Costello syndrome [RCV003514181]	likely benign	11	533751	533751	Human	1	name
405010631	CV2915442	single nucleotide variant	NM_005343.4(HRAS):c.290+15G>C	Costello syndrome [RCV003514925]	likely benign	11	533751	533751	Human	1	name
405013631	CV2921187	single nucleotide variant	NM_005343.4(HRAS):c.450+19C>T	Costello syndrome [RCV003515202]	likely benign	11	533434	533434	Human	1	name
402496845	CV2965888	single nucleotide variant	NM_005343.4(HRAS):c.111+15G>C	Costello syndrome [RCV003627839]	likely benign	11	534197	534197	Human	1	name
402497112	CV2966200	single nucleotide variant	NM_005343.4(HRAS):c.290+19G>T	Costello syndrome [RCV003627867]	likely benign	11	533747	533747	Human	1	name
405221846	CV3158182	single nucleotide variant	NM_005343.4(HRAS):c.290+11T>C	Costello syndrome [RCV003863678]	likely benign	11	533755	533755	Human	1	name
405249485	CV3170095	single nucleotide variant	NM_005343.4(HRAS):c.451-14C>A	Costello syndrome [RCV003869724]	likely benign	11	532769	532769	Human	1	name
405000808	CV3183978	single nucleotide variant	NM_005343.4(HRAS):c.291-11C>T	Costello syndrome [RCV003882561]	likely benign	11	533623	533623	Human	1	name
12846731	CV371488	single nucleotide variant	NM_005343.4(HRAS):c.450+18C>T	Costello syndrome [RCV002059560]\|not provided [RCV000442192]	likely benign	11	533435	533435	Human	1	name
12839713	CV374147	single nucleotide variant	NM_005343.4(HRAS):c.-53-17A>G	not provided [RCV000429334]	benign\|likely benign	11	534392	534392	Human		name
597969557	CV3753399	single nucleotide variant	NM_005343.4(HRAS):c.451-13C>G	Costello syndrome [RCV005083884]	likely benign	11	532768	532768	Human	1	name
597854672	CV3778875	single nucleotide variant	NM_005343.4(HRAS):c.450+12C>T	Costello syndrome [RCV005129220]	likely benign	11	533441	533441	Human	1	name
597854763	CV3778923	single nucleotide variant	NM_005343.4(HRAS):c.112-11T>C	Costello syndrome [RCV005129268]	likely benign	11	533955	533955	Human	1	name
597926002	CV3856468	single nucleotide variant	NM_005343.4(HRAS):c.290+20C>T	Costello syndrome [RCV005200533]	likely benign	11	533746	533746	Human	1	name
150485706	CV48899	single nucleotide variant	NM_005343.4(HRAS):c.-53-10T>C	not provided [RCV001715651]	benign	11	534385	534385	Human		name
8608134	CV48902	single nucleotide variant	NM_005343.4(HRAS):c.111+15G>A	Costello syndrome [RCV002054538]\|not provided [RCV001636610]\|not specified [RCV000038454]	benign	11	534197	534197	Human	1	name
150485731	CV48903	single nucleotide variant	NM_005343.4(HRAS):c.111+50C>G	not provided [RCV001715656]	benign	11	534162	534162	Human		name
150468204	CV48904	single nucleotide variant	NM_005343.4(HRAS):c.111+75C>G	not provided [RCV001650464]	benign	11	534137	534137	Human		name
13538494	CV503876	single nucleotide variant	NM_005343.4(HRAS):c.291-17C>G	Costello syndrome [RCV003767572]\|not specified [RCV000611909]	likely benign	11	533629	533629	Human	1	name
13529657	CV503878	single nucleotide variant	NM_005343.4(HRAS):c.111+14C>T	Costello syndrome [RCV002064333]\|not specified [RCV000600392]	likely benign	11	534198	534198	Human	1	name
13796762	CV552659	single nucleotide variant	NM_005343.4(HRAS):c.451-48C>T	not provided [RCV000680739]	likely benign	11	532803	532803	Human		name
15116581	CV744533	single nucleotide variant	NM_005343.4(HRAS):c.451-10C>T	Costello syndrome [RCV000895227]	likely benign	11	532765	532765	Human	1	name
15194268	CV775739	single nucleotide variant	NM_005343.4(HRAS):c.111+10G>A	Costello syndrome [RCV003514442]	likely benign	11	534202	534202	Human	1	name
38597919	CV861315	duplication	NM_005343.4(HRAS):c.450+38dup	Squamous cell lung carcinoma [RCV001250978]	uncertain significance	11	533414	533415	Human	2	name
38597921	CV861316	single nucleotide variant	NM_005343.4(HRAS):c.450+35A>C	Squamous cell lung carcinoma [RCV001250979]	uncertain significance	11	533418	533418	Human	2	name
38597923	CV861317	single nucleotide variant	NM_005343.4(HRAS):c.450+31A>G	Squamous cell lung carcinoma [RCV001250980]	uncertain significance	11	533422	533422	Human	2	name
38597924	CV861318	single nucleotide variant	NM_005343.4(HRAS):c.111+18G>C	Squamous cell lung carcinoma [RCV001250981]	uncertain significance	11	534194	534194	Human	2	name
34891285	CV906055	single nucleotide variant	NM_005343.4(HRAS):c.450+17C>T	Costello syndrome [RCV002559679]\|not specified [RCV001174936]	likely benign\|uncertain significance	11	533436	533436	Human	1	name
34896633	CV917487	single nucleotide variant	NM_005343.4(HRAS):c.450+20C>A	Costello syndrome [RCV002069249]\|not specified [RCV001194133]	likely benign\|uncertain significance	11	533433	533433	Human	1	name
34896629	CV917488	single nucleotide variant	NM_005343.4(HRAS):c.290+10G>A	Costello syndrome [RCV002559226]\|not specified [RCV001194131]	likely benign\|uncertain significance	11	533756	533756	Human	1	name
40903250	CV975806	single nucleotide variant	NM_005343.4(HRAS):c.112-13T>A	Costello syndrome [RCV002069390]\|not provided [RCV001683760]\|not specified [RCV001269170]	likely benign\|uncertain significance	11	533957	533957	Human	1	name
150514185	CV1228096	single nucleotide variant	NM_005343.4(HRAS):c.451-224G>A	not provided [RCV001638374]	benign	11	532979	532979	Human		name
9693607	CV175213	single nucleotide variant	NM_005343.4(HRAS):c.450+171C>T	not specified [RCV000156659]	not provided	11	533282	533282	Human		name
401946258	CV2839621	single nucleotide variant	NM_005343.4(HRAS):c.450+181G>A	Epidermolytic nevus [RCV003458963]	uncertain significance	11	533272	533272	Human		name
405274707	CV3209588	single nucleotide variant	NM_005343.4(HRAS):c.450+170T>G	HRAS-related disorder [RCV003951848]	likely benign	11	533283	533283	Human		name , trait , alternate_id
12848431	CV371486	single nucleotide variant	NM_005343.4(HRAS):c.450+174G>A	HRAS-related disorder [RCV003902493]\|not provided [RCV000445288]	likely benign	11	533279	533279	Human		name , trait , alternate_id
13796639	CV552660	single nucleotide variant	NM_005343.4(HRAS):c.451-168T>G	not provided [RCV000680678]	benign	11	532923	532923	Human		name
13797546	CV552661	single nucleotide variant	NM_005343.4(HRAS):c.451-282C>T	not provided [RCV000681305]	benign	11	533037	533037	Human		name
13796765	CV552662	single nucleotide variant	NM_005343.4(HRAS):c.451-341G>A	not provided [RCV000680741]	likely benign	11	533096	533096	Human		name
151805012	CV1444278	deletion	NM_005343.4(HRAS):c.110_111+5del	Costello syndrome [RCV001918065]	uncertain significance	11	534207	534213	Human	1	name
8568000	CV38866	duplication	NM_005343.4(HRAS):c.110_111+1dup	Costello syndrome [RCV000022797]	pathogenic	11	534210	534211	Human	1	name
12901611	CV408385	microsatellite	NM_005343.4(HRAS):c.-95CGGCCC[1]	not specified [RCV000485121]	benign	11	535446	535451	Human		name
150536418	CV1293057	microsatellite	NM_005343.4(HRAS):c.-54+103CGG[6]	not provided [RCV001762843]	benign	11	535290	535295	Human		name
152157092	CV1668956	deletion	NM_176795.5(HRAS):c.451-12_451del	not specified [RCV002223165]	uncertain significance	11	533358	533370	Human		name
402503552	CV3016782	deletion	NM_005343.4(HRAS):c.440_450+16del	Costello syndrome [RCV003628571]	uncertain significance	11	533437	533463	Human	1	name
152158732	CV1529100	single nucleotide variant	NM_005343.4(HRAS):c.6G>A (p.Thr2=)	Cardiovascular phenotype [RCV002373015]\|Costello syndrome [RCV002159247]	likely benign	11	534317	534317	Human	1	name
15170412	CV779542	microsatellite	NM_005343.4(HRAS):c.291-4_291-3del	Costello syndrome [RCV001401902]	likely benign	11	533615	533616	Human		name
26905478	CV852362	microsatellite	NM_005343.4(HRAS):c.112-7_112-5del	Costello syndrome [RCV001037002]	likely benign\|uncertain significance	11	533949	533951	Human		name
127245650	CV1078346	single nucleotide variant	NM_005343.4(HRAS):c.15G>A (p.Lys5=)	Cardiovascular phenotype [RCV002404980]\|Costello syndrome [RCV001416541]	likely benign	11	534308	534308	Human	1	name
150409896	CV1191238	single nucleotide variant	NM_005343.4(HRAS):c.24G>C (p.Val8=)	Costello syndrome [RCV002072165]\|not provided [RCV001565820]	likely benign	11	534299	534299	Human	1	name
152086419	CV1573882	duplication	NM_005343.4(HRAS):c.451-22_451-8dup	Costello syndrome [RCV002149986]	likely benign	11	532762	532763	Human	1	name
152035260	CV1590349	single nucleotide variant	NM_005343.4(HRAS):c.12T>C (p.Tyr4=)	Costello syndrome [RCV002205476]	likely benign	11	534311	534311	Human	1	name
155689800	CV1850591	single nucleotide variant	NM_005343.4(HRAS):c.21G>C (p.Val7=)	Cardiovascular phenotype [RCV002425716]\|Costello syndrome [RCV003098707]\|not provided [RCV002466758]	likely benign\|uncertain significance	11	534302	534302	Human	1	name
12890998	CV398321	single nucleotide variant	NM_005343.4(HRAS):c.16C>T (p.Leu6=)	Cardiovascular phenotype [RCV002411554]\|Costello syndrome [RCV001473659]	likely benign	11	534307	534307	Human	1	name
38597854	CV964672	deletion	NM_005343.4(HRAS):c.112-59_*6-51del	Costello syndrome [RCV001253224]	uncertain significance	11	532573	534003	Human	1	name
127233370	CV1078345	single nucleotide variant	NM_005343.4(HRAS):c.99C>T (p.Asp33=)	Costello syndrome [RCV001413845]	likely benign	11	534224	534224	Human	1	name
127276422	CV1100066	single nucleotide variant	NM_005343.4(HRAS):c.55C>T (p.Leu19=)	Costello syndrome [RCV001443802]	likely benign	11	534268	534268	Human	1	name
127323781	CV1121550	single nucleotide variant	NM_005343.4(HRAS):c.33C>T (p.Ala11=)	Costello syndrome [RCV001467991]	likely benign	11	534290	534290	Human	1	name
127298609	CV1121551	single nucleotide variant	NM_005343.4(HRAS):c.30C>T (p.Gly10=)	Costello syndrome [RCV001453365]	likely benign	11	534293	534293	Human	1	name
151804301	CV1444150	single nucleotide variant	NM_005343.4(HRAS):c.5C>G (p.Thr2Arg)	Costello syndrome [RCV001917995]	uncertain significance	11	534318	534318	Human	1	name
9690198	CV174804	single nucleotide variant	NM_005343.4(HRAS):c.45C>T (p.Gly15=)	Costello syndrome [RCV000818776]\|HRAS-related disorder [RCV003952786]\|Hereditary cancer-predisposing syndrome [RCV002257458]\|not provided [RCV000585962]\|not specified [RCV000155869]	likely benign\|uncertain significance	11	534278	534278	Human	2	name , trait , alternate_id
9689178	CV175216	single nucleotide variant	NM_005343.4(HRAS):c.36C>A (p.Gly12=)	not specified [RCV000154620]	not provided	11	534287	534287	Human		name
156359400	CV1904226	duplication	NM_005343.4(HRAS):c.25dup (p.Val9fs)	Costello syndrome [RCV002581623]	uncertain significance	11	534297	534298	Human	1	name
11039904	CV223774	single nucleotide variant	NM_005343.4(HRAS):c.36C>T (p.Gly12=)	Costello syndrome [RCV000207496]\|HRAS-related disorder [RCV003927887]\|Noonan syndrome and Noonan-related syndrome [RCV001813428]\|RASopathy [RCV000522904]\|not provided [RCV000586057]	pathogenic\|likely pathogenic\|benign\|likely benign\|conflicting interpretations of pathogenicity\|uncertain significance	11	534287	534287	Human	2	name , trait , alternate_id
11347479	CV241159	single nucleotide variant	NM_005343.4(HRAS):c.4A>G (p.Thr2Ala)	Costello syndrome [RCV000232309]	uncertain significance	11	534319	534319	Human	1	name
11544859	CV254211	single nucleotide variant	NM_005343.4(HRAS):c.57G>C (p.Leu19=)	Cardiovascular phenotype [RCV002356348]\|Costello syndrome [RCV000874891]\|not specified [RCV000244358]	likely benign	11	534266	534266	Human	1	name
11547182	CV254212	single nucleotide variant	NM_005343.4(HRAS):c.42G>A (p.Val14=)	Cardiovascular phenotype [RCV002328743]\|Costello syndrome [RCV000462480]\|not provided [RCV001597013]\|not specified [RCV000247431]	likely benign	11	534281	534281	Human	1	name
405009272	CV2860501	single nucleotide variant	NM_005343.4(HRAS):c.45C>G (p.Gly15=)	Costello syndrome [RCV003514704]	likely benign	11	534278	534278	Human	1	name
402494219	CV3074836	single nucleotide variant	NM_005343.4(HRAS):c.67C>T (p.Leu23=)	Costello syndrome [RCV003627545]	likely benign	11	534256	534256	Human	1	name
12844300	CV372233	single nucleotide variant	NM_005343.4(HRAS):c.54G>A (p.Ala18=)	Cardiovascular phenotype [RCV002348170]\|Costello syndrome [RCV001084746]\|not provided [RCV000437756]\|not specified [RCV001175031]	benign\|likely benign	11	534269	534269	Human	1	name
597930703	CV3851987	single nucleotide variant	NM_005343.4(HRAS):c.48G>A (p.Lys16=)	Costello syndrome [RCV005204967]	likely benign	11	534275	534275	Human	1	name
8608147	CV48901	single nucleotide variant	NM_005343.4(HRAS):c.81T>C (p.His27=)	Cardiovascular phenotype [RCV002426537]\|Costello syndrome [RCV000659682]\|Noonan syndrome and Noonan-related syndrome [RCV001813233]\|RASopathy [RCV000149841]\|Squamous cell lung carcinoma [RCV001250943]\|not provided [RCV000509400]\|not specified [RCV000038468]	benign\|likely benign\|conflicting interpretations of pathogenicity\|uncertain significance\|not provided	11	534242	534242	Human	4	name
13528930	CV503881	single nucleotide variant	NM_005343.4(HRAS):c.84T>C (p.Phe28=)	Costello syndrome [RCV001463449]\|not specified [RCV000600165]	likely benign	11	534239	534239	Human	1	name
13605872	CV526310	single nucleotide variant	NM_005343.4(HRAS):c.96C>T (p.Tyr32=)	Cardiovascular phenotype [RCV002386025]\|Costello syndrome [RCV000637312]\|not provided [RCV001564192]\|not specified [RCV000781470]	likely benign\|uncertain significance	11	534227	534227	Human	1	name
13796557	CV552665	deletion	NM_005343.4(HRAS):c.-53-40_-53-29del	not provided [RCV000680644]	benign	11	534404	534415	Human		name
13796559	CV552666	deletion	NM_005343.4(HRAS):c.-53-40_-53-35del	not provided [RCV000680646]	benign	11	534410	534415	Human		name
14728459	CV640158	single nucleotide variant	NM_005343.4(HRAS):c.5C>T (p.Thr2Met)	Costello syndrome [RCV000816525]	uncertain significance	11	534318	534318	Human	1	name
15124549	CV693060	single nucleotide variant	NM_005343.4(HRAS):c.90C>T (p.Asp30=)	Costello syndrome [RCV000874791]	likely benign	11	534233	534233	Human	1	name
15105657	CV693061	single nucleotide variant	NM_005343.4(HRAS):c.69G>A (p.Leu23=)	Costello syndrome [RCV000871145]\|not specified [RCV001420954]	likely benign	11	534254	534254	Human	1	name
15119704	CV693062	single nucleotide variant	NM_005343.4(HRAS):c.60C>T (p.Thr20=)	Costello syndrome [RCV000873928]	likely benign	11	534263	534263	Human	1	name
15105267	CV701803	single nucleotide variant	NM_005343.4(HRAS):c.54G>C (p.Ala18=)	Costello syndrome [RCV001502715]	likely benign	11	534269	534269	Human	1	name
127238397	CV1078342	single nucleotide variant	NM_005343.4(HRAS):c.261C>T (p.Thr87=)	Cardiovascular phenotype [RCV002456666]\|Costello syndrome [RCV001415096]\|not provided [RCV004801008]	likely benign\|uncertain significance	11	533795	533795	Human	1	name
127268581	CV1078343	single nucleotide variant	NM_005343.4(HRAS):c.159G>A (p.Leu53=)	Costello syndrome [RCV001404417]	likely benign	11	533897	533897	Human	1	name
127279433	CV1100060	single nucleotide variant	NM_005343.4(HRAS):c.288C>T (p.Tyr96=)	Costello syndrome [RCV001445773]	likely benign	11	533768	533768	Human	1	name
127246123	CV1100061	single nucleotide variant	NM_005343.4(HRAS):c.279C>T (p.Ile93=)	Costello syndrome [RCV001435343]	likely benign	11	533777	533777	Human	1	name
127267667	CV1100062	single nucleotide variant	NM_005343.4(HRAS):c.222C>G (p.Thr74=)	Costello syndrome [RCV001429768]	likely benign	11	533834	533834	Human	1	name
127258569	CV1100063	single nucleotide variant	NM_005343.4(HRAS):c.198C>T (p.Ala66=)	Costello syndrome [RCV001438160]	likely benign	11	533858	533858	Human	1	name
127283141	CV1100064	single nucleotide variant	NM_005343.4(HRAS):c.147G>A (p.Glu49=)	Cardiovascular phenotype [RCV002396039]\|Costello syndrome [RCV001448313]\|not specified [RCV005237822]	likely benign	11	533909	533909	Human	1	name
127282231	CV1100065	single nucleotide variant	NM_005343.4(HRAS):c.123G>C (p.Arg41=)	Cardiovascular phenotype [RCV002384695]\|Costello syndrome [RCV001447692]	likely benign	11	533933	533933	Human	1	name
127335421	CV1121543	single nucleotide variant	NM_005343.4(HRAS):c.297G>A (p.Gln99=)	Cardiovascular phenotype [RCV002439133]\|Costello syndrome [RCV001474289]	likely benign	11	533606	533606	Human	1	name
127294375	CV1121544	single nucleotide variant	NM_005343.4(HRAS):c.258C>T (p.Asn86=)	Costello syndrome [RCV001452227]	likely benign	11	533798	533798	Human	1	name
127318402	CV1121545	single nucleotide variant	NM_005343.4(HRAS):c.255C>T (p.Asn85=)	Cardiovascular phenotype [RCV002432305]\|Costello syndrome [RCV001466181]	likely benign	11	533801	533801	Human	1	name
127292911	CV1121546	single nucleotide variant	NM_005343.4(HRAS):c.235C>T (p.Leu79=)	Costello syndrome [RCV001459074]	likely benign	11	533821	533821	Human	1	name
127292836	CV1121547	single nucleotide variant	NM_005343.4(HRAS):c.192C>T (p.Tyr64=)	Cardiovascular phenotype [RCV004995846]\|Costello syndrome [RCV001459048]\|HRAS-related disorder [RCV003965911]\|not specified [RCV002282553]	likely benign	11	533864	533864	Human	1	name , trait , alternate_id
127314533	CV1121548	single nucleotide variant	NM_005343.4(HRAS):c.177C>G (p.Ala59=)	Costello syndrome [RCV001457720]	likely benign	11	533879	533879	Human	1	name
127334957	CV1121549	single nucleotide variant	NM_005343.4(HRAS):c.165C>T (p.Ile55=)	Costello syndrome [RCV001473943]	likely benign	11	533891	533891	Human	1	name
127336650	CV1142411	single nucleotide variant	NM_005343.4(HRAS):c.273G>A (p.Glu91=)	Costello syndrome [RCV001492334]	likely benign	11	533783	533783	Human	1	name
127299817	CV1142412	single nucleotide variant	NM_005343.4(HRAS):c.202C>A (p.Arg68=)	Costello syndrome [RCV001498417]	likely benign	11	533854	533854	Human	1	name
151748478	CV1353219	single nucleotide variant	NM_005343.4(HRAS):c.11A>C (p.Tyr4Ser)	Costello syndrome [RCV001912723]	uncertain significance	11	534312	534312	Human	1	name
152050475	CV1527775	single nucleotide variant	NM_005343.4(HRAS):c.166C>T (p.Leu56=)	Costello syndrome [RCV002089090]	likely benign	11	533890	533890	Human	1	name
152143507	CV1557016	single nucleotide variant	NM_005343.4(HRAS):c.138T>C (p.Ile46=)	Costello syndrome [RCV002200887]	likely benign	11	533918	533918	Human	1	name
152035125	CV1582924	single nucleotide variant	NM_005343.4(HRAS):c.210G>A (p.Gln70=)	Costello syndrome [RCV002106859]	likely benign	11	533846	533846	Human	1	name
152133337	CV1585229	single nucleotide variant	NM_005343.4(HRAS):c.237G>T (p.Leu79=)	Costello syndrome [RCV002083168]	likely benign	11	533819	533819	Human	1	name
152050269	CV1585702	single nucleotide variant	NM_005343.4(HRAS):c.150G>T (p.Thr50=)	Cardiovascular phenotype [RCV002391278]\|Costello syndrome [RCV002145600]	likely benign	11	533906	533906	Human	1	name
152097117	CV1587042	single nucleotide variant	NM_005343.4(HRAS):c.249C>G (p.Ala83=)	Costello syndrome [RCV002078499]	likely benign	11	533807	533807	Human	1	name
152159805	CV1588277	single nucleotide variant	NM_005343.4(HRAS):c.195C>T (p.Ser65=)	Costello syndrome [RCV002180731]	likely benign	11	533861	533861	Human	1	name
152047720	CV1619952	single nucleotide variant	NM_005343.4(HRAS):c.126G>A (p.Lys42=)	Costello syndrome [RCV002207120]	likely benign	11	533930	533930	Human	1	name
155643744	CV1709540	single nucleotide variant	NM_005343.4(HRAS):c.243G>T (p.Val81=)	Prostate cancer, hereditary, 1 [RCV002292423]	uncertain significance	11	533813	533813	Human	1	name
155721355	CV1776444	single nucleotide variant	NM_005343.4(HRAS):c.19G>T (p.Val7Leu)	Costello syndrome [RCV002296714]	uncertain significance	11	534304	534304	Human	1	name
9832731	CV179418	single nucleotide variant	NM_005343.4(HRAS):c.177C>T (p.Ala59=)	Cardiovascular phenotype [RCV002408711]\|Costello syndrome [RCV000470354]\|Hereditary cancer-predisposing syndrome [RCV002258815]\|Noonan syndrome and Noonan-related syndrome [RCV001813409]\|not provided [RCV003390854]\|not specified [RCV000157907]	benign\|likely benign\|conflicting interpretations of pathogenicity	11	533879	533879	Human	2	name
155680009	CV1853143	single nucleotide variant	NM_005343.4(HRAS):c.276C>T (p.Asp92=)	Cardiovascular phenotype [RCV002439594]	likely benign	11	533780	533780	Human		name
156419401	CV1932766	single nucleotide variant	NM_005343.4(HRAS):c.294G>A (p.Glu98=)	Costello syndrome [RCV002612633]	likely benign\|uncertain significance	11	533609	533609	Human	1	name
156409573	CV1961851	single nucleotide variant	NM_005343.4(HRAS):c.243G>A (p.Val81=)	Costello syndrome [RCV002586862]	likely benign	11	533813	533813	Human	1	name
156077388	CV2011852	single nucleotide variant	NM_005343.4(HRAS):c.183G>A (p.Gln61=)	Cardiovascular phenotype [RCV005351004]\|Costello syndrome [RCV002705877]	likely benign	11	533873	533873	Human	1	name
155950882	CV2013982	single nucleotide variant	NM_005343.4(HRAS):c.157T>C (p.Leu53=)	Costello syndrome [RCV002686015]	likely benign	11	533899	533899	Human	1	name
155904587	CV2084082	single nucleotide variant	NM_005343.4(HRAS):c.150G>C (p.Thr50=)	Costello syndrome [RCV002858072]	likely benign	11	533906	533906	Human	1	name
156265213	CV2100898	single nucleotide variant	NM_005343.4(HRAS):c.291G>A (p.Arg97=)	Costello syndrome [RCV002877412]	likely benign\|uncertain significance	11	533612	533612	Human	1	name
156161815	CV2135397	single nucleotide variant	NM_005343.4(HRAS):c.225G>C (p.Gly75=)	Cardiovascular phenotype [RCV005343565]\|Costello syndrome [RCV002983034]	likely benign	11	533831	533831	Human	1	name
11546795	CV254210	single nucleotide variant	NM_005343.4(HRAS):c.171T>C (p.Asp57=)	Costello syndrome [RCV000871401]\|Hereditary cancer-predisposing syndrome [RCV002258867]\|not specified [RCV000246927]	likely benign\|uncertain significance	11	533885	533885	Human	2	name
405004725	CV2882696	single nucleotide variant	NM_005343.4(HRAS):c.189G>A (p.Glu63=)	Costello syndrome [RCV003514223]	likely benign	11	533867	533867	Human	1	name
402488381	CV2943811	single nucleotide variant	NM_005343.4(HRAS):c.135C>T (p.Val45=)	Cardiovascular phenotype [RCV004992683]\|Costello syndrome [RCV003626915]	likely benign	11	533921	533921	Human	1	name
402499794	CV2990236	single nucleotide variant	NM_005343.4(HRAS):c.105T>C (p.Thr35=)	Costello syndrome [RCV003628152]	likely benign	11	534218	534218	Human	1	name
597717828	CV3689505	single nucleotide variant	NM_005343.4(HRAS):c.213C>T (p.Tyr71=)	Cardiovascular phenotype [RCV004991730]\|Costello syndrome [RCV005110359]	likely benign	11	533843	533843	Human	1	name
12837120	CV371490	single nucleotide variant	NM_005343.4(HRAS):c.234C>T (p.Phe78=)	Costello syndrome [RCV002059794]\|not provided [RCV000424616]	likely benign	11	533822	533822	Human	1	name
12839006	CV371492	single nucleotide variant	NM_005343.4(HRAS):c.150G>A (p.Thr50=)	Costello syndrome [RCV002061575]\|not provided [RCV000428021]	likely benign	11	533906	533906	Human	1	name
12836353	CV372231	single nucleotide variant	NM_005343.4(HRAS):c.228G>A (p.Glu76=)	Costello syndrome [RCV002063360]\|not provided [RCV000423251]	likely benign	11	533828	533828	Human	1	name
12844471	CV372462	single nucleotide variant	NM_005343.4(HRAS):c.162C>T (p.Asp54=)	Costello syndrome [RCV003514353]\|HRAS-related disorder [RCV003897851]\|not specified [RCV000438047]	likely benign	11	533894	533894	Human	1	name , trait , alternate_id
597842597	CV3775042	single nucleotide variant	NM_005343.4(HRAS):c.285G>A (p.Gln95=)	Costello syndrome [RCV005117868]	likely benign	11	533771	533771	Human	1	name
598192735	CV3971947	single nucleotide variant	NM_005343.4(HRAS):c.204G>A (p.Arg68=)	Cardiovascular phenotype [RCV005354513]	likely benign	11	533852	533852	Human		name
12888755	CV398226	single nucleotide variant	NM_005343.4(HRAS):c.219C>T (p.Arg73=)	Cardiovascular phenotype [RCV002431368]\|Costello syndrome [RCV000471546]\|HRAS-related disorder [RCV003899987]\|not provided [RCV003392297]\|not specified [RCV005239056]	likely benign	11	533837	533837	Human	1	name , trait , alternate_id
12882820	CV398227	single nucleotide variant	NM_005343.4(HRAS):c.156G>A (p.Leu52=)	Cardiovascular phenotype [RCV004992255]\|Costello syndrome [RCV000460380]\|not provided [RCV001613309]	benign\|likely benign	11	533900	533900	Human	1	name
12880796	CV398679	single nucleotide variant	NM_005343.4(HRAS):c.120C>T (p.Tyr40=)	Costello syndrome [RCV000456682]\|not provided [RCV001310581]	likely benign	11	533936	533936	Human	1	name
13488113	CV461207	single nucleotide variant	NM_005343.4(HRAS):c.156G>T (p.Leu52=)	Cardiovascular phenotype [RCV003380607]\|Costello syndrome [RCV001497959]	likely benign	11	533900	533900	Human	1	name
13521868	CV487541	single nucleotide variant	NM_005343.4(HRAS):c.10T>C (p.Tyr4His)	not provided [RCV000590817]	uncertain significance	11	534313	534313	Human		name
13519923	CV487566	single nucleotide variant	NM_005343.4(HRAS):c.222C>T (p.Thr74=)	Cardiovascular phenotype [RCV002431742]\|Costello syndrome [RCV001082400]\|not provided [RCV000586814]	benign\|likely benign	11	533834	533834	Human	1	name
13520279	CV494970	single nucleotide variant	NM_005343.4(HRAS):c.11A>G (p.Tyr4Cys)	Costello syndrome [RCV001322927]\|Large congenital melanocytic nevus [RCV002483665]\|not specified [RCV000598510]	uncertain significance	11	534312	534312	Human	7	name
13605871	CV526264	single nucleotide variant	NM_005343.4(HRAS):c.153C>T (p.Cys51=)	Cardiovascular phenotype [RCV002404781]\|Costello syndrome [RCV000637311]	likely benign	11	533903	533903	Human	1	name
13605869	CV526298	single nucleotide variant	NM_005343.4(HRAS):c.141T>C (p.Asp47=)	Cardiovascular phenotype [RCV002388047]\|Costello syndrome [RCV000637306]\|not specified [RCV001194129]	likely benign	11	533915	533915	Human	1	name
13605873	CV526306	single nucleotide variant	NM_005343.4(HRAS):c.102C>T (p.Pro34=)	Cardiovascular phenotype [RCV002386026]\|Costello syndrome [RCV000637314]\|Noonan syndrome and Noonan-related syndrome [RCV001813533]	likely benign	11	534221	534221	Human	1	name
8608135	CV54465	single nucleotide variant	NM_005343.4(HRAS):c.249C>T (p.Ala83=)	Cardiovascular phenotype [RCV003162337]\|Costello syndrome [RCV000531092]\|HRAS-related disorder [RCV003964858]\|Hereditary cancer-predisposing syndrome [RCV002257382]\|not provided [RCV004597734]\|not specified [RCV000038455]	likely benign	11	533807	533807	Human	2	name , trait , alternate_id
8608136	CV54466	single nucleotide variant	NM_005343.4(HRAS):c.282C>T (p.His94=)	Cardiovascular phenotype [RCV002433504]\|Costello syndrome [RCV001458613]\|HRAS-related disorder [RCV003894865]\|not provided [RCV005243107]\|not specified [RCV000038456]	likely benign	11	533774	533774	Human	1	name , trait , alternate_id
15138651	CV687787	single nucleotide variant	NM_005343.4(HRAS):c.174C>T (p.Thr58=)	Cardiovascular phenotype [RCV002409032]\|Costello syndrome [RCV000864872]	likely benign	11	533882	533882	Human	1	name
15157081	CV687788	single nucleotide variant	NM_005343.4(HRAS):c.102C>G (p.Pro34=)	Costello syndrome [RCV001493838]\|not provided [RCV000868366]	likely benign\|conflicting interpretations of pathogenicity\|uncertain significance	11	534221	534221	Human	1	name
15130463	CV693059	single nucleotide variant	NM_005343.4(HRAS):c.237G>A (p.Leu79=)	Cardiovascular phenotype [RCV002454037]\|Costello syndrome [RCV000875822]	likely benign	11	533819	533819	Human	1	name
15132061	CV712873	single nucleotide variant	NM_005343.4(HRAS):c.144G>A (p.Gly48=)	Costello syndrome [RCV001483338]	likely benign	11	533912	533912	Human	1	name
15195861	CV752702	single nucleotide variant	NM_005343.4(HRAS):c.231C>T (p.Gly77=)	Costello syndrome [RCV000911535]	likely benign	11	533825	533825	Human	1	name
126735089	CV1009740	single nucleotide variant	NM_005343.4(HRAS):c.426C>A (p.Ile142=)	Costello syndrome [RCV001324473]	likely benign\|uncertain significance	11	533477	533477	Human	1	name
126916954	CV1047288	duplication	NM_005343.4(HRAS):c.108dup (p.Glu37fs)	Costello syndrome [RCV001371797]\|not provided [RCV005256783]	uncertain significance	11	534214	534215	Human	1	name
127282745	CV1078337	single nucleotide variant	NM_005343.4(HRAS):c.483T>C (p.Arg161=)	Costello syndrome [RCV001411333]	likely benign	11	532723	532723	Human	1	name
127283302	CV1078338	single nucleotide variant	NM_005343.4(HRAS):c.420C>T (p.Pro140=)	Costello syndrome [RCV001411688]\|not specified [RCV005419122]	likely benign	11	533483	533483	Human	1	name
127253537	CV1078339	single nucleotide variant	NM_005343.4(HRAS):c.399C>T (p.Leu133=)	Costello syndrome [RCV001400583]	likely benign	11	533504	533504	Human	1	name
127262861	CV1078340	single nucleotide variant	NM_005343.4(HRAS):c.390T>G (p.Ala130=)	Costello syndrome [RCV001402800]	likely benign	11	533513	533513	Human	1	name
127277283	CV1078341	single nucleotide variant	NM_005343.4(HRAS):c.375G>C (p.Val125=)	Costello syndrome [RCV001407667]	likely benign	11	533528	533528	Human	1	name
127275652	CV1100055	single nucleotide variant	NM_005343.4(HRAS):c.438C>A (p.Ala146=)	Costello syndrome [RCV001432469]	likely benign	11	533465	533465	Human	1	name
127271403	CV1100056	single nucleotide variant	NM_005343.4(HRAS):c.417C>T (p.Ile139=)	Costello syndrome [RCV001430947]	likely benign	11	533486	533486	Human	1	name
127277918	CV1100057	single nucleotide variant	NM_005343.4(HRAS):c.414C>A (p.Gly138=)	Costello syndrome [RCV001444684]	likely benign	11	533489	533489	Human	1	name
127272257	CV1100058	single nucleotide variant	NM_005343.4(HRAS):c.318G>A (p.Ser106=)	Cardiovascular phenotype [RCV004995815]\|Costello syndrome [RCV001442126]	likely benign	11	533585	533585	Human	1	name
127315195	CV1121538	single nucleotide variant	NM_005343.4(HRAS):c.567C>G (p.Ser189=)	Costello syndrome [RCV001465161]	likely benign	11	532639	532639	Human	1	name
127299309	CV1121539	single nucleotide variant	NM_005343.4(HRAS):c.489C>A (p.Ile163=)	Costello syndrome [RCV001453562]	likely benign	11	532717	532717	Human	1	name
127305161	CV1121540	single nucleotide variant	NM_005343.4(HRAS):c.396C>T (p.Asp132=)	Costello syndrome [RCV001455181]	likely benign	11	533507	533507	Human	1	name
127324653	CV1121541	single nucleotide variant	NM_005343.4(HRAS):c.393G>A (p.Gln131=)	Costello syndrome [RCV001468249]	likely benign	11	533510	533510	Human	1	name
127293456	CV1121542	single nucleotide variant	NM_005343.4(HRAS):c.366A>G (p.Ala122=)	Costello syndrome [RCV001459233]	likely benign	11	533537	533537	Human	1	name
127326639	CV1142405	single nucleotide variant	NM_005343.4(HRAS):c.465C>T (p.Ala155=)	Costello syndrome [RCV001486095]	likely benign	11	532741	532741	Human	1	name
127316498	CV1142406	single nucleotide variant	NM_005343.4(HRAS):c.435G>C (p.Ser145=)	Costello syndrome [RCV001503034]	likely benign	11	533468	533468	Human	1	name
127302193	CV1142407	single nucleotide variant	NM_005343.4(HRAS):c.402C>G (p.Ala134=)	Costello syndrome [RCV001499031]	likely benign	11	533501	533501	Human	1	name
127332035	CV1142408	single nucleotide variant	NM_005343.4(HRAS):c.360G>C (p.Leu120=)	Cardiovascular phenotype [RCV002456867]\|Costello syndrome [RCV001489223]	likely benign	11	533543	533543	Human	1	name
127327297	CV1142409	single nucleotide variant	NM_005343.4(HRAS):c.345G>A (p.Gly115=)	Costello syndrome [RCV001506532]	likely benign	11	533558	533558	Human	1	name
150428518	CV1187758	single nucleotide variant	NM_176795.5(HRAS):c.501G>A (p.Pro167=)	not provided [RCV001562363]	likely benign	11	533308	533308	Human		name
150502400	CV1254518	single nucleotide variant	NM_176795.5(HRAS):c.498C>G (p.Pro166=)	not provided [RCV001677220]	likely benign	11	533311	533311	Human		name
151845901	CV1341917	single nucleotide variant	NM_005343.4(HRAS):c.44G>C (p.Gly15Ala)	Costello syndrome [RCV001922109]	uncertain significance	11	534279	534279	Human	1	name
151853779	CV1376363	single nucleotide variant	NM_005343.4(HRAS):c.88G>A (p.Asp30Asn)	Costello syndrome [RCV001996287]	uncertain significance	11	534235	534235	Human	1	name
151713422	CV1384111	single nucleotide variant	NM_005343.4(HRAS):c.99C>A (p.Asp33Glu)	Costello syndrome [RCV001908473]	uncertain significance	11	534224	534224	Human	1	name
151823285	CV1385471	single nucleotide variant	NM_005343.4(HRAS):c.375G>A (p.Val125=)	Costello syndrome [RCV001975953]	likely benign\|uncertain significance	11	533528	533528	Human	1	name
151769521	CV1410600	single nucleotide variant	NM_005343.4(HRAS):c.543C>T (p.Cys181=)	Costello syndrome [RCV001988101]	likely benign\|uncertain significance	11	532663	532663	Human	1	name
151800661	CV1474888	single nucleotide variant	NM_005343.4(HRAS):c.414C>T (p.Gly138=)	Costello syndrome [RCV001952892]	likely benign\|uncertain significance	11	533489	533489	Human	1	name
152086907	CV1531848	single nucleotide variant	NM_005343.4(HRAS):c.540C>T (p.Gly180=)	Costello syndrome [RCV002077104]	likely benign	11	532666	532666	Human	1	name
152170961	CV1536771	single nucleotide variant	NM_005343.4(HRAS):c.342G>C (p.Val114=)	Costello syndrome [RCV002183336]	likely benign	11	533561	533561	Human	1	name
152145122	CV1543231	single nucleotide variant	NM_005343.4(HRAS):c.447G>A (p.Arg149=)	Costello syndrome [RCV002178605]	likely benign	11	533456	533456	Human	1	name
152094078	CV1561416	single nucleotide variant	NM_005343.4(HRAS):c.324C>T (p.Asp108=)	Costello syndrome [RCV002094596]	likely benign	11	533579	533579	Human	1	name
152175999	CV1562141	single nucleotide variant	NM_005343.4(HRAS):c.564C>G (p.Leu188=)	Costello syndrome [RCV002164139]	likely benign	11	532642	532642	Human	1	name
152088874	CV1563001	single nucleotide variant	NM_005343.4(HRAS):c.304C>A (p.Arg102=)	Costello syndrome [RCV002113793]	likely benign	11	533599	533599	Human	1	name
152057659	CV1567358	single nucleotide variant	NM_005343.4(HRAS):c.315C>T (p.Asp105=)	Costello syndrome [RCV002146422]\|not specified [RCV005239293]	likely benign	11	533588	533588	Human	1	name
152148758	CV1569121	single nucleotide variant	NM_005343.4(HRAS):c.462T>C (p.Asp154=)	Cardiovascular phenotype [RCV002337232]\|Costello syndrome [RCV002220462]	likely benign	11	532744	532744	Human	1	name
152059484	CV1597646	single nucleotide variant	NM_005343.4(HRAS):c.480G>C (p.Val160=)	Costello syndrome [RCV002128170]	likely benign	11	532726	532726	Human	1	name
152137719	CV1603782	single nucleotide variant	NM_005343.4(HRAS):c.495G>A (p.Gln165=)	Costello syndrome [RCV002218948]	likely benign	11	532711	532711	Human	1	name
152156235	CV1615731	single nucleotide variant	NM_005343.4(HRAS):c.408C>T (p.Ser136=)	Costello syndrome [RCV002158888]	likely benign	11	533495	533495	Human	1	name
152041040	CV1627807	single nucleotide variant	NM_005343.4(HRAS):c.459G>A (p.Glu153=)	Costello syndrome [RCV002188265]	likely benign	11	532747	532747	Human	1	name
152104703	CV1658732	single nucleotide variant	NM_005343.4(HRAS):c.555G>A (p.Lys185=)	Costello syndrome [RCV002152245]	likely benign	11	532651	532651	Human	1	name
152122799	CV1664282	single nucleotide variant	NM_005343.4(HRAS):c.300C>T (p.Ile100=)	Cardiovascular phenotype [RCV002434578]\|Costello syndrome [RCV002154476]	likely benign	11	533603	533603	Human	1	name
155643741	CV1709537	deletion	NM_005343.4(HRAS):c.146del (p.Glu49fs)	Prostate cancer, hereditary, 1 [RCV002292420]	uncertain significance	11	533910	533910	Human	1	name
9689988	CV175217	single nucleotide variant	NM_005343.4(HRAS):c.31G>A (p.Ala11Thr)	Cardiovascular phenotype [RCV004019863]\|Costello syndrome [RCV000694918]\|not specified [RCV000155632]	uncertain significance	11	534292	534292	Human	1	name
9831513	CV179419	single nucleotide variant	NM_005343.4(HRAS):c.38G>T (p.Gly13Val)	Costello syndrome [RCV000590121]\|KA-like vemurafenib-induced squamous lesions [RCV001849323]\|Large congenital melanocytic nevus [RCV004562310]\|Linear nevus sebaceous syndrome [RCV004767097]\|Lip and oral cavity carcinoma [RCV001255688]\|not provided [RCV000157914]	pathogenic\|likely pathogenic	11	534285	534285	Human	7	name
156363736	CV1881555	single nucleotide variant	NM_005343.4(HRAS):c.330C>A (p.Pro110=)	Costello syndrome [RCV003065809]	likely benign	11	533573	533573	Human	1	name
156332175	CV1884536	single nucleotide variant	NM_005343.4(HRAS):c.438C>T (p.Ala146=)	Costello syndrome [RCV003089864]	likely benign	11	533465	533465	Human	1	name
156441481	CV1944138	single nucleotide variant	NM_005343.4(HRAS):c.55C>A (p.Leu19Met)	Costello syndrome [RCV003111807]	uncertain significance	11	534268	534268	Human	1	name
156122682	CV1952810	single nucleotide variant	NM_005343.4(HRAS):c.531T>C (p.Ser177=)	Costello syndrome [RCV002571927]	likely benign	11	532675	532675	Human	1	name
156116773	CV1972862	single nucleotide variant	NM_005343.4(HRAS):c.567C>T (p.Ser189=)	Costello syndrome [RCV002592978]	likely benign	11	532639	532639	Human	1	name
156049046	CV2006639	single nucleotide variant	NM_005343.4(HRAS):c.402C>T (p.Ala134=)	Costello syndrome [RCV002659302]	likely benign	11	533501	533501	Human	1	name
155947378	CV2036019	single nucleotide variant	NM_005343.4(HRAS):c.534C>T (p.Gly178=)	Costello syndrome [RCV002775568]	likely benign	11	532672	532672	Human	1	name
156026948	CV2078177	single nucleotide variant	NM_005343.4(HRAS):c.540C>A (p.Gly180=)	Costello syndrome [RCV002866882]	likely benign	11	532666	532666	Human	1	name
156194757	CV2175443	single nucleotide variant	NM_005343.4(HRAS):c.44G>T (p.Gly15Val)	Costello syndrome [RCV003057955]	uncertain significance	11	534279	534279	Human	1	name
156396931	CV2178287	single nucleotide variant	NM_005343.4(HRAS):c.351G>A (p.Lys117=)	Costello syndrome [RCV003051932]	likely benign	11	533552	533552	Human	1	name
11096307	CV230220	single nucleotide variant	NM_005343.4(HRAS):c.468C>T (p.Phe156=)	Cardiovascular phenotype [RCV005338112]\|Costello syndrome [RCV002517470]\|not specified [RCV000223407]	likely benign	11	532738	532738	Human	1	name
11349413	CV241155	single nucleotide variant	NM_005343.4(HRAS):c.339G>A (p.Leu113=)	Costello syndrome [RCV001490462]	likely benign	11	533564	533564	Human	1	name
11543251	CV254209	single nucleotide variant	NM_005343.4(HRAS):c.369C>T (p.Arg123=)	Cardiovascular phenotype [RCV002347960]\|Costello syndrome [RCV001079542]\|Hereditary cancer-predisposing syndrome [RCV002257620]\|Noonan syndrome and Noonan-related syndrome [RCV001813437]\|RASopathy [RCV000520797]\|not provided [RCV000588992]\|not specified [RCV000242213]	benign\|likely benign	11	533534	533534	Human	3	name
11636492	CV264487	single nucleotide variant	NM_005343.4(HRAS):c.64C>T (p.Gln22Ter)	not provided [RCV000269895]	likely benign\|uncertain significance	11	534259	534259	Human		name
401766034	CV2732135	single nucleotide variant	NM_005343.4(HRAS):c.432C>T (p.Thr144=)	Cardiovascular phenotype [RCV003301684]	likely benign	11	533471	533471	Human		name
8563222	CV27639	single nucleotide variant	NM_005343.4(HRAS):c.35G>T (p.Gly12Val)	Cardiovascular phenotype [RCV004018622]\|Costello syndrome [RCV000013432]\|Epidermal nevus [RCV000032850]\|HRAS-related disorder [RCV003415692]\|Malignant tumor of urinary bladder [RCV000013431]\|Myopathy, congenital, with excess of muscle spindles [RCV000013433]\|not ... (more) provided [RCV000157912]	pathogenic\|likely pathogenic\|other	11	534288	534288	Human	7	name , trait , alternate_id
8563224	CV27641	single nucleotide variant	NM_005343.4(HRAS):c.34G>A (p.Gly12Ser)	Cardiovascular phenotype [RCV002453256]\|Costello syndrome [RCV000013435]\|Epidermal nevus [RCV003450636]\|Epidermal nevus with urothelial cancer, somatic [RCV000022796]\|HRAS-related disorder [RCV003398496]\|Large congenital melanocytic nevus [RCV004795404]\|Lip and ... (more) oral cavity carcinoma [RCV001255689]\|Myopathy, congenital, with excess of muscle spindles [RCV000013436]\|Nevus sebaceous [RCV000029209]\|Noonan syndrome 1 [RCV003450635]\|Noonan syndrome and Noonan-related syndrome [RCV001813185]\|RASopathy [RCV000149828]\|Rhabdomyosarcoma [RCV001257537]\|See cases [RCV003156059]\|Wooly hair nevus [RCV000487471]\|not provided [RCV000081295]	pathogenic\|likely pathogenic\|other	11	534289	534289	Human	22	name , trait , alternate_id
8563225	CV27642	single nucleotide variant	NM_005343.4(HRAS):c.35G>C (p.Gly12Ala)	Costello syndrome [RCV000013437]\|Inborn genetic diseases [RCV000623953]\|Large congenital melanocytic nevus [RCV000762848]\|Noonan syndrome and Noonan-related syndrome [RCV001813186]\|Rhabdomyosarcoma [RCV001257536]\|not provided [RCV000207503]	pathogenic\|likely pathogenic	11	534288	534288	Human	17	name
8563226	CV27643	single nucleotide variant	NM_005343.4(HRAS):c.38G>A (p.Gly13Asp)	Costello syndrome [RCV000013438]\|HRAS-related disorder [RCV003390677]\|Large congenital melanocytic nevus [RCV002476960]\|Non-immune hydrops fetalis [RCV001376018]\|Noonan syndrome and Noonan-related syndrome [RCV001813187]\|RASopathy [RCV000781469]\|not provided [RC ... (more) V000157913]	pathogenic\|likely pathogenic\|not provided	11	534285	534285	Human	17	name , trait , alternate_id
8599073	CV27645	single nucleotide variant	NM_005343.4(HRAS):c.37G>T (p.Gly13Cys)	Costello syndrome [RCV000013440]\|HRAS-related disorder [RCV003421918]\|Large congenital melanocytic nevus [RCV000762847]\|Linear nevus sebaceous syndrome [RCV004767004]\|Noonan syndrome [RCV000678903]\|Noonan syndrome and Noonan-related syndrome [RCV001813188]\|RASop ... (more) athy [RCV000149831]\|not provided [RCV000207504]	pathogenic\|likely pathogenic	11	534286	534286	Human	16	name , trait , alternate_id
8563229	CV27648	single nucleotide variant	NM_005343.4(HRAS):c.64C>A (p.Gln22Lys)	Costello syndrome [RCV000143898]\|Myopathy, congenital, with excess of muscle spindles [RCV000013443]\|not provided [RCV000157915]	pathogenic\|likely pathogenic	11	534259	534259	Human	2	name
8563231	CV27651	single nucleotide variant	NM_005343.4(HRAS):c.35G>A (p.Gly12Asp)	Costello syndrome [RCV000038460]\|Costello syndrome, severe [RCV000013446]\|HRAS-related disorder [RCV004739303]\|Lip and oral cavity carcinoma [RCV001255681]\|Nevus sebaceous [RCV000029210]\|Non-immune hydrops fetalis [RCV001375956]\|Noonan syndrome and Noonan-relate ... (more) d syndrome [RCV001813189]\|RASopathy [RCV000149830]\|not provided [RCV000212496]	pathogenic\|likely pathogenic\|other	11	534288	534288	Human	7	name , trait , alternate_id
8569126	CV27652	single nucleotide variant	NM_005343.4(HRAS):c.34G>T (p.Gly12Cys)	Costello syndrome [RCV000013447]\|Epidermal nevus [RCV000032851]\|Large congenital melanocytic nevus [RCV000762849]\|Nevus sebaceous [RCV000029211]\|RASopathy [RCV000149829]\|not provided [RCV000212495]	pathogenic\|likely pathogenic\|other	11	534289	534289	Human	10	name
401904006	CV2806382	single nucleotide variant	NM_005343.4(HRAS):c.483T>G (p.Arg161=)	not provided [RCV003394672]	likely benign	11	532723	532723	Human		name
405007991	CV2863699	single nucleotide variant	NM_005343.4(HRAS):c.59C>T (p.Thr20Ile)	Costello syndrome [RCV003514667]	uncertain significance	11	534264	534264	Human	1	name
405003483	CV2888703	single nucleotide variant	NM_005343.4(HRAS):c.342G>A (p.Val114=)	Costello syndrome [RCV003514117]	likely benign	11	533561	533561	Human	1	name
402499377	CV2983125	single nucleotide variant	NM_005343.4(HRAS):c.91G>C (p.Glu31Gln)	Costello syndrome [RCV003628135]	uncertain significance	11	534232	534232	Human	1	name
402490931	CV3049003	single nucleotide variant	NM_005343.4(HRAS):c.429G>A (p.Glu143=)	Costello syndrome [RCV003627206]	likely benign	11	533474	533474	Human	1	name
402486229	CV3050208	single nucleotide variant	NM_005343.4(HRAS):c.474G>C (p.Thr158=)	Costello syndrome [RCV003626581]	likely benign	11	532732	532732	Human	1	name
402499551	CV3077857	single nucleotide variant	NM_005343.4(HRAS):c.306G>A (p.Arg102=)	Costello syndrome [RCV003628098]	likely benign	11	533597	533597	Human	1	name
405010035	CV3127988	single nucleotide variant	NM_005343.4(HRAS):c.74A>G (p.Gln25Arg)	Costello syndrome [RCV003828868]	uncertain significance	11	534249	534249	Human	1	name
405031586	CV3130255	single nucleotide variant	NM_005343.4(HRAS):c.522T>C (p.Pro174=)	Costello syndrome [RCV003830662]	likely benign	11	532684	532684	Human	1	name
405145049	CV3141479	single nucleotide variant	NM_005343.4(HRAS):c.445C>A (p.Arg149=)	Costello syndrome [RCV003839596]	uncertain significance	11	533458	533458	Human	1	name
405292767	CV3193128	single nucleotide variant	NM_005343.4(HRAS):c.306G>C (p.Arg102=)	HRAS-related disorder [RCV003964692]	likely benign	11	533597	533597	Human		name , trait , alternate_id
407528317	CV3433920	single nucleotide variant	NM_005343.4(HRAS):c.387G>A (p.Gln129=)	Cardiovascular phenotype [RCV004633109]	likely benign	11	533516	533516	Human		name
12835378	CV362840	single nucleotide variant	NM_005343.4(HRAS):c.34G>C (p.Gly12Arg)	Costello syndrome [RCV002230756]	pathogenic\|likely pathogenic	11	534289	534289	Human	1	name
12834339	CV363202	single nucleotide variant	NM_005343.4(HRAS):c.37G>A (p.Gly13Ser)	Costello syndrome [RCV002524694]\|Vascular Tumors Including Pyogenic Granuloma [RCV000662270]	likely pathogenic	11	534286	534286	Human	1	name
12835267	CV363322	single nucleotide variant	NM_005343.4(HRAS):c.38G>C (p.Gly13Ala)	Acute myeloid leukemia [RCV000424186]\|B-cell chronic lymphocytic leukemia [RCV000426316]\|Gastric adenocarcinoma [RCV000421384]\|Hepatocellular carcinoma [RCV000445345]\|Lung adenocarcinoma [RCV000434457]\|Malignant neoplasm of body of uterus [RCV000434248]\|Multiple myeloma [RCV000442365]\|Neoplasm of th ... (more) e large intestine [RCV000440965]\|Neoplasm of uterine cervix [RCV000433957]\|Pancreatic adenocarcinoma [RCV000425652]	likely pathogenic	11	534285	534285	Human	8	name
12842336	CV371489	single nucleotide variant	NM_005343.4(HRAS):c.426C>T (p.Ile142=)	Cardiovascular phenotype [RCV002328927]\|Costello syndrome [RCV002524810]\|not provided [RCV000434218]	likely benign	11	533477	533477	Human	1	name
12836329	CV372230	single nucleotide variant	NM_176795.5(HRAS):c.480C>T (p.Ser160=)	not provided [RCV000423204]	likely benign	11	533329	533329	Human		name
598232052	CV3893188	single nucleotide variant	NM_005343.4(HRAS):c.68T>G (p.Leu23Arg)	Costello syndrome [RCV005255547]	likely pathogenic	11	534255	534255	Human	1	name
12888890	CV398222	single nucleotide variant	NM_005343.4(HRAS):c.537C>T (p.Pro179=)	Cardiovascular phenotype [RCV004992254]\|Costello syndrome [RCV000471783]\|not provided [RCV001576338]	likely benign	11	532669	532669	Human	1	name
12884980	CV398316	single nucleotide variant	NM_005343.4(HRAS):c.534C>G (p.Gly178=)	Cardiovascular phenotype [RCV002350036]\|Costello syndrome [RCV000464492]\|HRAS-related disorder [RCV003970343]\|not provided [RCV001575546]\|not specified [RCV001420905]	likely benign	11	532672	532672	Human	1	name , trait , alternate_id
12883067	CV398318	single nucleotide variant	NM_005343.4(HRAS):c.516C>T (p.Asn172=)	Costello syndrome [RCV000460869]\|not specified [RCV000610082]	likely benign	11	532690	532690	Human	1	name
12885599	CV398657	single nucleotide variant	NM_005343.4(HRAS):c.519T>G (p.Pro173=)	Costello syndrome [RCV000465686]	likely benign	11	532687	532687	Human	1	name
12883887	CV398766	single nucleotide variant	NM_005343.4(HRAS):c.312G>A (p.Lys104=)	Cardiovascular phenotype [RCV004992256]\|Costello syndrome [RCV000462463]\|not provided [RCV001613310]	likely benign	11	533591	533591	Human	1	name
8569127	CV44227	single nucleotide variant	NM_005343.4(HRAS):c.37G>C (p.Gly13Arg)	Costello syndrome [RCV001781319]\|Epidermal nevus [RCV000032852]\|Epidermolytic nevus [RCV003458340]\|HRAS-related disorder [RCV004739310]\|Linear nevus sebaceous syndrome [RCV000029213]\|Lip and oral cavity carcinoma [RCV001255682]\|NEVUS SPILUS, SOMATIC [RCV00017300 ... (more) 5]\|Nevus sebaceous [RCV000029212]\|Non-immune hydrops fetalis [RCV001376004]\|Noonan syndrome and Noonan-related syndrome [RCV001813211]\|SPITZ NEVUS, SOMATIC [RCV000173006]\|cutaneous-skeletal hypophosphatemia syndrome [RCV001849283]	pathogenic\|likely pathogenic\|other	11	534286	534286	Human	10	name , trait , alternate_id
13501393	CV461200	single nucleotide variant	NM_005343.4(HRAS):c.474G>A (p.Thr158=)	Cardiovascular phenotype [RCV005338231]\|Costello syndrome [RCV001463916]	likely benign	11	532732	532732	Human	1	name
13495553	CV461203	single nucleotide variant	NM_005343.4(HRAS):c.435G>A (p.Ser145=)	Cardiovascular phenotype [RCV004023889]\|Costello syndrome [RCV000537215]	likely benign	11	533468	533468	Human	1	name
13473171	CV462038	single nucleotide variant	NM_005343.4(HRAS):c.441G>A (p.Lys147=)	Cardiovascular phenotype [RCV002330854]\|Costello syndrome [RCV001494759]\|not provided [RCV004707323]	likely benign	11	533462	533462	Human	1	name
11346165	CV48910	single nucleotide variant	NM_005343.4(HRAS):c.309G>A (p.Val103=)	Costello syndrome [RCV000227548]\|HRAS-related disorder [RCV003894842]\|Noonan syndrome and Noonan-related syndrome [RCV001813235]\|RASopathy [RCV000519223]\|not provided [RCV001711138]	benign\|likely benign	11	533594	533594	Human	2	name , trait , alternate_id
8608138	CV48911	single nucleotide variant	NM_005343.4(HRAS):c.357C>T (p.Asp119=)	Cardiovascular phenotype [RCV002453280]\|Costello syndrome [RCV000227939]\|HRAS-related disorder [RCV003924885]\|Hereditary cancer-predisposing syndrome [RCV002257371]\|Large congenital melanocytic nevus [RCV002477043]\|Noonan syndrome and Noonan-related syndrome [RC ... (more) V001813236]\|RASopathy [RCV000522686]\|not provided [RCV001711139]\|not specified [RCV000038458]	benign\|likely benign	11	533546	533546	Human	16	name , trait , alternate_id
8608141	CV48912	single nucleotide variant	NM_005343.4(HRAS):c.378A>G (p.Glu126=)	Cardiovascular phenotype [RCV002345262]\|Costello syndrome [RCV001081660]\|Noonan syndrome and Noonan-related syndrome [RCV001813237]\|RASopathy [RCV000519017]\|not provided [RCV000588072]\|not specified [RCV000038462]	benign\|likely benign	11	533525	533525	Human	2	name
8608144	CV48916	single nucleotide variant	NM_005343.4(HRAS):c.477G>A (p.Leu159=)	Cardiovascular phenotype [RCV002336104]\|Costello syndrome [RCV000234776]\|Hereditary cancer-predisposing syndrome [RCV002257372]\|Noonan syndrome and Noonan-related syndrome [RCV001813238]\|RASopathy [RCV000522477]\|not provided [RCV001538584]\|not specified [RCV000038465]	benign\|likely benign\|conflicting interpretations of pathogenicity	11	532729	532729	Human	3	name
13605870	CV526483	single nucleotide variant	NM_005343.4(HRAS):c.411C>T (p.Tyr137=)	Costello syndrome [RCV000637307]	likely benign	11	533492	533492	Human	1	name
13703160	CV539147	single nucleotide variant	NM_005343.4(HRAS):c.44G>A (p.Gly15Asp)	Vascular Tumors Including Pyogenic Granuloma [RCV000662271]	uncertain significance	11	534279	534279	Human		name
8608137	CV54467	single nucleotide variant	NM_005343.4(HRAS):c.330C>T (p.Pro110=)	Cardiovascular phenotype [RCV002321512]\|Costello syndrome [RCV000467667]\|HRAS-related disorder [RCV004739326]\|Large congenital melanocytic nevus [RCV002490523]\|Noonan syndrome and Noonan-related syndrome [RCV001813351]\|not specified [RCV000038457]	benign\|likely benign\|conflicting interpretations of pathogenicity	11	533573	533573	Human	14	name , trait , alternate_id
8608139	CV54468	single nucleotide variant	NM_005343.4(HRAS):c.358C>T (p.Leu120=)	Cardiovascular phenotype [RCV003362675]\|Costello syndrome [RCV000457956]\|not specified [RCV000038459]	likely benign	11	533545	533545	Human	1	name
8608140	CV54469	single nucleotide variant	NM_005343.4(HRAS):c.363T>C (p.Ala121=)	Cardiovascular phenotype [RCV004018873]\|Costello syndrome [RCV000560800]\|Noonan syndrome and Noonan-related syndrome [RCV001813352]\|not provided [RCV001659973]\|not specified [RCV000038461]	benign\|likely benign	11	533540	533540	Human	1	name
8608145	CV54472	single nucleotide variant	NM_005343.4(HRAS):c.510G>A (p.Lys170=)	Cardiovascular phenotype [RCV003162338]\|Costello syndrome [RCV000473658]\|RASopathy [RCV000520548]\|not specified [RCV000038466]	benign\|likely benign\|conflicting interpretations of pathogenicity	11	532696	532696	Human	2	name
14712555	CV640157	single nucleotide variant	NM_005343.4(HRAS):c.41T>G (p.Val14Gly)	Costello syndrome [RCV000810329]	uncertain significance	11	534282	534282	Human	1	name
15194390	CV701802	single nucleotide variant	NM_005343.4(HRAS):c.492G>A (p.Arg164=)	Costello syndrome [RCV000955635]\|not specified [RCV005236479]	likely benign	11	532714	532714	Human	1	name
15200610	CV768485	single nucleotide variant	NM_005343.4(HRAS):c.423C>T (p.Tyr141=)	Cardiovascular phenotype [RCV004629387]\|Costello syndrome [RCV001400667]	likely benign	11	533480	533480	Human	1	name
38485103	CV926275	single nucleotide variant	NM_005343.4(HRAS):c.97G>A (p.Asp33Asn)	Costello syndrome [RCV001219408]	uncertain significance	11	534226	534226	Human	1	name
126728028	CV1009744	single nucleotide variant	NM_005343.4(HRAS):c.236T>A (p.Leu79Gln)	Costello syndrome [RCV001312421]	uncertain significance	11	533820	533820	Human	1	name
126768148	CV1009745	single nucleotide variant	NM_005343.4(HRAS):c.203G>T (p.Arg68Leu)	Costello syndrome [RCV001321198]	uncertain significance	11	533853	533853	Human	1	name
126737231	CV1020875	single nucleotide variant	NM_005343.4(HRAS):c.134T>A (p.Val45Asp)	Cardiovascular phenotype [RCV003169563]\|Costello syndrome [RCV001335259]	uncertain significance	11	533922	533922	Human	1	name
126774747	CV1030305	single nucleotide variant	NM_005343.4(HRAS):c.260C>T (p.Thr87Ile)	Costello syndrome [RCV001347584]	uncertain significance	11	533796	533796	Human	1	name
126913668	CV1047286	single nucleotide variant	NM_005343.4(HRAS):c.211T>C (p.Tyr71His)	Costello syndrome [RCV001370190]	uncertain significance	11	533845	533845	Human	1	name
126917823	CV1047287	single nucleotide variant	NM_005343.4(HRAS):c.202C>G (p.Arg68Gly)	Cardiovascular phenotype [RCV002420839]\|Costello syndrome [RCV001372298]	uncertain significance	11	533854	533854	Human	1	name
126916897	CV1047289	single nucleotide variant	NM_005343.4(HRAS):c.101C>T (p.Pro34Leu)	Costello syndrome [RCV001360851]	uncertain significance	11	534222	534222	Human	1	name
151352139	CV1325102	single nucleotide variant	NM_005343.4(HRAS):c.175G>T (p.Ala59Ser)	Costello syndrome [RCV002541490]\|Noonan syndrome and Noonan-related syndrome [RCV001813657]	uncertain significance	11	533881	533881	Human	1	name
151714239	CV1330556	single nucleotide variant	NM_005343.4(HRAS):c.278T>C (p.Ile93Thr)	Parathyroid gland adenoma [RCV001843332]	uncertain significance	11	533778	533778	Human	4	name
151890890	CV1346807	single nucleotide variant	NM_005343.4(HRAS):c.145G>C (p.Glu49Gln)	Costello syndrome [RCV002038934]	uncertain significance	11	533911	533911	Human	1	name
151862952	CV1365172	single nucleotide variant	NM_005343.4(HRAS):c.136A>G (p.Ile46Val)	Costello syndrome [RCV002017989]\|not provided [RCV003332372]	uncertain significance	11	533920	533920	Human	1	name
151812531	CV1376890	single nucleotide variant	NM_005343.4(HRAS):c.223G>A (p.Gly75Arg)	Costello syndrome [RCV001900092]	uncertain significance	11	533833	533833	Human	1	name
151836019	CV1382991	single nucleotide variant	NM_005343.4(HRAS):c.285G>C (p.Gln95His)	Costello syndrome [RCV001935564]	uncertain significance	11	533771	533771	Human	1	name
151799677	CV1396584	deletion	NM_005343.4(HRAS):c.445del (p.Arg149fs)	Costello syndrome [RCV001917597]	uncertain significance	11	533458	533458	Human	1	name
151874502	CV1408420	single nucleotide variant	NM_005343.4(HRAS):c.202C>T (p.Arg68Trp)	Costello syndrome [RCV001906898]\|not provided [RCV003235615]	likely pathogenic\|uncertain significance	11	533854	533854	Human	1	name
151795093	CV1435603	single nucleotide variant	NM_005343.4(HRAS):c.292G>A (p.Glu98Lys)	Costello syndrome [RCV001931785]	uncertain significance	11	533611	533611	Human	1	name
151889144	CV1509500	single nucleotide variant	NM_005343.4(HRAS):c.107T>C (p.Ile36Thr)	Costello syndrome [RCV001888117]	uncertain significance	11	534216	534216	Human	1	name
151861255	CV1511180	single nucleotide variant	NM_005343.4(HRAS):c.127C>T (p.Gln43Ter)	Costello syndrome [RCV001959252]	uncertain significance	11	533929	533929	Human	1	name
151865163	CV1511634	single nucleotide variant	NM_005343.4(HRAS):c.103A>G (p.Thr35Ala)	Costello syndrome [RCV001997641]	uncertain significance	11	534220	534220	Human	1	name
151757455	CV1514193	single nucleotide variant	NM_005343.4(HRAS):c.115T>A (p.Ser39Thr)	Costello syndrome [RCV001948765]	uncertain significance	11	533941	533941	Human	1	name
152122457	CV1554962	single nucleotide variant	NM_005343.4(HRAS):c.284A>G (p.Gln95Arg)	Costello syndrome [RCV002198241]	likely benign	11	533772	533772	Human	1	name
153002530	CV1685328	single nucleotide variant	NM_005343.4(HRAS):c.221C>T (p.Thr74Ile)	Costello syndrome [RCV003774794]\|Hereditary cancer-predisposing syndrome [RCV002259278]	uncertain significance	11	533835	533835	Human	2	name
9684519	CV170209	single nucleotide variant	NM_005343.4(HRAS):c.182A>G (p.Gln61Arg)	Large congenital melanocytic nevus [RCV004796045]\|Linear nevus sebaceous syndrome [RCV000148033]\|Noonan syndrome and Noonan-related syndrome [RCV001813393]\|Salivary gland neoplasm [RCV001844808]\|Vascular Tumors Including Pyogenic Granuloma [RCV000662268]\|not provided [RCV000157918]	pathogenic\|likely pathogenic\|uncertain significance\|not provided	11	533874	533874	Human	16	name
155645940	CV1709298	single nucleotide variant	NM_005343.4(HRAS):c.262A>T (p.Lys88Ter)	not provided [RCV002292174]	uncertain significance	11	533794	533794	Human		name
155643743	CV1709539	single nucleotide variant	NM_005343.4(HRAS):c.170A>C (p.Asp57Ala)	Prostate cancer, hereditary, 1 [RCV002292422]	uncertain significance	11	533886	533886	Human	1	name
155643745	CV1709541	single nucleotide variant	NM_005343.4(HRAS):c.199A>T (p.Met67Leu)	Prostate cancer, hereditary, 1 [RCV002292424]	uncertain significance	11	533857	533857	Human	1	name
9832736	CV179417	single nucleotide variant	NM_005343.4(HRAS):c.203G>A (p.Arg68Gln)	Costello syndrome [RCV000557317]\|not provided [RCV004696860]\|not specified [RCV002271424]	likely pathogenic\|uncertain significance	11	533853	533853	Human	1	name
401722611	CV1867353	single nucleotide variant	NM_005343.4(HRAS):c.176C>G (p.Ala59Gly)	RASopathy [RCV003238902]	pathogenic	11	533880	533880	Human	1	name
155958320	CV1873513	single nucleotide variant	NM_005343.4(HRAS):c.194G>A (p.Ser65Asn)	Costello syndrome [RCV003074548]	uncertain significance	11	533862	533862	Human	1	name
156145308	CV1895080	single nucleotide variant	NM_005343.4(HRAS):c.178G>C (p.Gly60Arg)	Costello syndrome [RCV003082358]	uncertain significance	11	533878	533878	Human	1	name
156197279	CV1912390	single nucleotide variant	NM_005343.4(HRAS):c.230G>A (p.Gly77Asp)	Costello syndrome [RCV002595577]	uncertain significance	11	533826	533826	Human	1	name
156439209	CV1944075	single nucleotide variant	NM_005343.4(HRAS):c.220A>G (p.Thr74Ala)	Costello syndrome [RCV003109166]	uncertain significance	11	533836	533836	Human	1	name
156115691	CV1952324	single nucleotide variant	NM_005343.4(HRAS):c.250A>G (p.Ile84Val)	Costello syndrome [RCV002571664]	uncertain significance	11	533806	533806	Human	1	name
156070788	CV2018541	single nucleotide variant	NM_005343.4(HRAS):c.189G>C (p.Glu63Asp)	Costello syndrome [RCV002705677]	uncertain significance	11	533867	533867	Human	1	name
156207568	CV2040325	single nucleotide variant	NM_005343.4(HRAS):c.122G>C (p.Arg41Pro)	Costello syndrome [RCV002790114]	uncertain significance	11	533934	533934	Human	1	name
156155655	CV2049286	single nucleotide variant	NM_005343.4(HRAS):c.253A>G (p.Asn85Asp)	Costello syndrome [RCV002801443]	uncertain significance	11	533803	533803	Human	1	name
156052197	CV2064605	single nucleotide variant	NM_005343.4(HRAS):c.262A>G (p.Lys88Glu)	Costello syndrome [RCV002846474]	uncertain significance	11	533794	533794	Human	1	name
156259739	CV2100536	duplication	NM_005343.4(HRAS):c.191dup (p.Tyr64Ter)	Costello syndrome [RCV002877228]	uncertain significance	11	533864	533865	Human	1	name
156343607	CV2124097	single nucleotide variant	NM_005343.4(HRAS):c.215T>C (p.Met72Thr)	Costello syndrome [RCV002939038]	uncertain significance	11	533841	533841	Human	1	name
156280288	CV2137530	single nucleotide variant	NM_005343.4(HRAS):c.247G>A (p.Ala83Thr)	Costello syndrome [RCV003009575]	uncertain significance	11	533809	533809	Human	1	name
156152395	CV2175438	single nucleotide variant	NM_005343.4(HRAS):c.151T>C (p.Cys51Arg)	Costello syndrome [RCV003040416]	uncertain significance	11	533905	533905	Human	1	name
156285008	CV2187093	single nucleotide variant	NM_005343.4(HRAS):c.218G>A (p.Arg73His)	Costello syndrome [RCV003044909]	uncertain significance	11	533838	533838	Human	1	name
8563223	CV27640	single nucleotide variant	NM_005343.4(HRAS):c.181C>A (p.Gln61Lys)	Epidermal nevus [RCV004562206]\|Lip and oral cavity carcinoma [RCV001255683]\|Noonan syndrome 3 [RCV000587258]\|Spermatocytic seminoma [RCV000022795]\|Thyroid cancer, nonmedullary, 2 [RCV000013434]\|not provided [RCV000681435]	pathogenic\|likely pathogenic\|other	11	533875	533875	Human	7	name
8563228	CV27647	single nucleotide variant	NM_005343.4(HRAS):c.187G>A (p.Glu63Lys)	Costello syndrome [RCV002272015]\|Myopathy, congenital, with excess of muscle spindles [RCV000013442]\|not provided [RCV000485616]	pathogenic	11	533869	533869	Human	2	name
8599074	CV27649	single nucleotide variant	NM_005343.4(HRAS):c.173C>T (p.Thr58Ile)	Costello syndrome [RCV000013444]\|HRAS-related disorder [RCV004724738]\|RASopathy [RCV005252034]\|not provided [RCV003221783]	pathogenic	11	533883	533883	Human	2	name , trait , alternate_id
405010972	CV2904416	single nucleotide variant	NM_005343.4(HRAS):c.131T>C (p.Val44Ala)	Costello syndrome [RCV003514885]	uncertain significance	11	533925	533925	Human	1	name
405012219	CV2913760	single nucleotide variant	NM_005343.4(HRAS):c.146A>G (p.Glu49Gly)	Costello syndrome [RCV003515072]	uncertain significance	11	533910	533910	Human	1	name
405020319	CV2925424	single nucleotide variant	NM_005343.4(HRAS):c.122G>A (p.Arg41Gln)	Costello syndrome [RCV003515838]	uncertain significance	11	533934	533934	Human	1	name
405021229	CV2926265	single nucleotide variant	NM_005343.4(HRAS):c.129G>C (p.Gln43His)	Costello syndrome [RCV003515930]	uncertain significance	11	533927	533927	Human	1	name
405021490	CV2932307	single nucleotide variant	NM_005343.4(HRAS):c.158T>G (p.Leu53Trp)	Costello syndrome [RCV003515956]	uncertain significance	11	533898	533898	Human	1	name
402497335	CV2976712	deletion	NM_005343.4(HRAS):c.373del (p.Val125fs)	Costello syndrome [RCV003627893]	uncertain significance	11	533530	533530	Human	1	name
402501147	CV2996237	single nucleotide variant	NM_005343.4(HRAS):c.158T>A (p.Leu53Ter)	Costello syndrome [RCV003628322]	uncertain significance	11	533898	533898	Human	1	name
402501751	CV3000479	single nucleotide variant	NM_005343.4(HRAS):c.201G>A (p.Met67Ile)	Costello syndrome [RCV003628373]	uncertain significance	11	533855	533855	Human	1	name
402503186	CV3013202	single nucleotide variant	NM_005343.4(HRAS):c.197C>T (p.Ala66Val)	Costello syndrome [RCV003628532]	uncertain significance	11	533859	533859	Human	1	name
402484831	CV3041355	single nucleotide variant	NM_005343.4(HRAS):c.295C>T (p.Gln99Ter)	Costello syndrome [RCV003626439]	uncertain significance	11	533608	533608	Human	1	name
402486375	CV3043658	single nucleotide variant	NM_005343.4(HRAS):c.221C>G (p.Thr74Ser)	Costello syndrome [RCV003626595]	uncertain significance	11	533835	533835	Human	1	name
405029623	CV3129917	single nucleotide variant	NM_005343.4(HRAS):c.217C>T (p.Arg73Cys)	Costello syndrome [RCV003830515]	uncertain significance	11	533839	533839	Human	1	name
407424973	CV3411019	duplication	NM_005343.4(HRAS):c.445dup (p.Arg149fs)	not provided [RCV004588709]	uncertain significance	11	533457	533458	Human		name
408388147	CV3520661	single nucleotide variant	NM_005343.4(HRAS):c.195C>G (p.Ser65Arg)	not provided [RCV004761494]	uncertain significance	11	533861	533861	Human		name
596927729	CV3532675	single nucleotide variant	NM_005343.4(HRAS):c.104C>T (p.Thr35Ile)	not provided [RCV004778773]	uncertain significance	11	534219	534219	Human		name
12834697	CV362912	single nucleotide variant	NM_005343.4(HRAS):c.182A>T (p.Gln61Leu)	Costello syndrome [RCV001372584]\|KA-like vemurafenib-induced squamous lesions [RCV001849368]\|Lip and oral cavity carcinoma [RCV001255684]	pathogenic\|likely pathogenic\|uncertain significance	11	533874	533874	Human	2	name
12834935	CV363197	single nucleotide variant	NM_005343.4(HRAS):c.183G>T (p.Gln61His)	Noonan syndrome 3 [RCV000589258]	likely pathogenic	11	533873	533873	Human	1	name
12839001	CV363198	single nucleotide variant	NM_005343.4(HRAS):c.183G>C (p.Gln61His)	Neoplasm [RCV000428014]	likely pathogenic	11	533873	533873	Human	1	name
12834311	CV363201	single nucleotide variant	NM_005343.4(HRAS):c.182A>C (p.Gln61Pro)	Acute myeloid leukemia [RCV000428741]\|B-cell chronic lymphocytic leukemia [RCV000424105]\|Gastric adenocarcinoma [RCV000435489]\|Hepatocellular carcinoma [RCV000440764]\|Lung adenocarcinoma [RCV000441832]\|Malignant melanoma of skin [RCV000430658]\|Malignant neoplasm of body of uterus [RCV000430030]\|Mult ... (more) iple myeloma [RCV000420448]\|Neoplasm [RCV000428681]\|Neoplasm of the large intestine [RCV000425877]\|Pancreatic adenocarcinoma [RCV000419094]\|Squamous cell lung carcinoma [RCV000435915]\|Thyroid tumor [RCV000435275]\|Transitional cell carcinoma of the bladder [RCV000417619]	likely pathogenic	11	533874	533874	Human	13	name
12834908	CV363323	single nucleotide variant	NM_005343.4(HRAS):c.181C>G (p.Gln61Glu)	Acute myeloid leukemia [RCV000435578]\|B-cell chronic lymphocytic leukemia [RCV000420757]\|Gastric adenocarcinoma [RCV000431015]\|Hepatocellular carcinoma [RCV000427302]\|Lung adenocarcinoma [RCV000444619]\|Malignant melanoma of skin [RCV000422470]\|Malignant neoplasm of body of uterus [RCV000442518]\|Mult ... (more) iple myeloma [RCV000444550]\|Neoplasm of the large intestine [RCV000437532]\|Pancreatic adenocarcinoma [RCV000423098]\|Squamous cell lung carcinoma [RCV000432499]\|Thyroid tumor [RCV000424391]\|Transitional cell carcinoma of the bladder [RCV000432733]	likely pathogenic	11	533875	533875	Human	12	name
12850259	CV374144	single nucleotide variant	NM_005343.4(HRAS):c.179G>T (p.Gly60Val)	Costello syndrome [RCV005090865]\|Large congenital melanocytic nevus [RCV002060067]\|not provided [RCV000443979]	pathogenic	11	533877	533877	Human	7	name
597966514	CV3751597	single nucleotide variant	NM_005343.4(HRAS):c.139G>A (p.Asp47Asn)	Costello syndrome [RCV005082967]	uncertain significance	11	533917	533917	Human	1	name
597904449	CV3839077	single nucleotide variant	NM_005343.4(HRAS):c.149C>T (p.Thr50Met)	Costello syndrome [RCV005179162]	uncertain significance	11	533907	533907	Human	1	name
12890843	CV398682	single nucleotide variant	NM_005343.4(HRAS):c.106A>G (p.Ile36Val)	Costello syndrome [RCV000475424]	uncertain significance	11	534217	534217	Human	1	name
9691715	CV48905	single nucleotide variant	NM_005343.4(HRAS):c.175G>A (p.Ala59Thr)	Costello syndrome [RCV000150835]\|Non-small cell lung carcinoma [RCV000150834]\|RASopathy [RCV004760350]	likely pathogenic\|conflicting interpretations of pathogenicity	11	533881	533881	Human	4	name
9832735	CV48906	single nucleotide variant	NM_005343.4(HRAS):c.179G>A (p.Gly60Asp)	Costello syndrome [RCV001387769]\|not provided [RCV000157917]	pathogenic	11	533877	533877	Human	1	name
9689087	CV48907	single nucleotide variant	NM_005343.4(HRAS):c.257A>C (p.Asn86Thr)	Costello syndrome [RCV001085194]\|HRAS-related disorder [RCV003944864]\|Hereditary cancer-predisposing syndrome [RCV002257370]\|Noonan syndrome [RCV001261051]\|Noonan syndrome and Noonan-related syndrome [RCV001813234]\|RASopathy [RCV000519779]\|not provided [RCV00068 ... (more) 0288]\|not specified [RCV000154506]	benign\|likely benign\|conflicting interpretations of pathogenicity\|uncertain significance	11	533799	533799	Human	4	name , trait , alternate_id
11039905	CV48908	single nucleotide variant	NM_005343.4(HRAS):c.266C>G (p.Ser89Cys)	not provided [RCV000207497]	likely pathogenic	11	533790	533790	Human		name
9586841	CV48909	single nucleotide variant	NM_005343.4(HRAS):c.277A>G (p.Ile93Val)	Costello syndrome [RCV000524082]\|Pulmonic stenosis [RCV000143899]\|RASopathy [RCV004760351]\|not provided [RCV000157920]	likely benign\|uncertain significance	11	533779	533779	Human	4	name
13527931	CV513316	duplication	NM_176795.5(HRAS):c.500dup (p.Pro169fs)	Congenital fibrosis of extraocular muscles [RCV003883157]\|Costello syndrome [RCV000625815]	pathogenic\|uncertain significance	11	533308	533309	Human	3	name
13605867	CV526481	duplication	NM_005343.4(HRAS):c.552dup (p.Lys185fs)	Costello syndrome [RCV000637304]	uncertain significance	11	532653	532654	Human	1	name
13703159	CV539145	single nucleotide variant	NM_005343.4(HRAS):c.145G>A (p.Glu49Lys)	Costello syndrome [RCV002530595]\|Vascular Tumors Including Pyogenic Granuloma [RCV000662269]	likely pathogenic\|uncertain significance	11	533911	533911	Human	1	name
13703161	CV539146	single nucleotide variant	NM_005343.4(HRAS):c.100C>T (p.Pro34Ser)	Vascular Tumors Including Pyogenic Granuloma [RCV000662272]	uncertain significance	11	534223	534223	Human		name
13797295	CV552663	single nucleotide variant	NM_005343.4(HRAS):c.137T>C (p.Ile46Thr)	Costello syndrome [RCV001861890]\|not provided [RCV000681108]	likely pathogenic\|uncertain significance	11	533919	533919	Human	1	name
13813842	CV570706	single nucleotide variant	NM_005343.4(HRAS):c.238T>A (p.Cys80Ser)	Costello syndrome [RCV000704627]	uncertain significance	11	533818	533818	Human	1	name
14393681	CV609793	single nucleotide variant	NM_005343.4(HRAS):c.214A>C (p.Met72Leu)	Costello syndrome [RCV005056501]\|not provided [RCV000756250]	uncertain significance	11	533842	533842	Human	1	name
14743746	CV640155	single nucleotide variant	NM_005343.4(HRAS):c.275A>C (p.Asp92Ala)	Costello syndrome [RCV000823640]	uncertain significance	11	533781	533781	Human	1	name
14732220	CV640156	single nucleotide variant	NM_005343.4(HRAS):c.178G>A (p.Gly60Ser)	Costello syndrome [RCV000818197]	likely pathogenic\|uncertain significance	11	533878	533878	Human	1	name
26917036	CV838563	single nucleotide variant	NM_005343.4(HRAS):c.282C>G (p.His94Gln)	Cardiovascular phenotype [RCV004031788]\|Costello syndrome [RCV001056731]	uncertain significance	11	533774	533774	Human	1	name
26895536	CV838564	single nucleotide variant	NM_005343.4(HRAS):c.280C>T (p.His94Tyr)	Costello syndrome [RCV001069666]	uncertain significance	11	533776	533776	Human	1	name
26886955	CV838565	single nucleotide variant	NM_005343.4(HRAS):c.133G>A (p.Val45Ile)	Costello syndrome [RCV001044559]	uncertain significance	11	533923	533923	Human	1	name
38493267	CV926274	single nucleotide variant	NM_005343.4(HRAS):c.260C>A (p.Thr87Asn)	Costello syndrome [RCV001224158]	uncertain significance	11	533796	533796	Human	1	name
38488591	CV935598	single nucleotide variant	NM_005343.4(HRAS):c.274G>A (p.Asp92Asn)	Costello syndrome [RCV001209828]	uncertain significance	11	533782	533782	Human	1	name
38475491	CV935599	single nucleotide variant	NM_005343.4(HRAS):c.263A>G (p.Lys88Arg)	Costello syndrome [RCV001204299]	uncertain significance	11	533793	533793	Human	1	name
38480299	CV935600	single nucleotide variant	NM_005343.4(HRAS):c.245T>G (p.Phe82Cys)	Costello syndrome [RCV001206337]	uncertain significance	11	533811	533811	Human	1	name
38470724	CV947502	single nucleotide variant	NM_005343.4(HRAS):c.297G>T (p.Gln99His)	Costello syndrome [RCV001231060]	uncertain significance	11	533606	533606	Human	1	name
38473071	CV947503	duplication	NM_005343.4(HRAS):c.270dup (p.Glu91Ter)	Costello syndrome [RCV001231755]	uncertain significance	11	533785	533786	Human	1	name
38493339	CV956532	single nucleotide variant	NM_005343.4(HRAS):c.295C>G (p.Gln99Glu)	Costello syndrome [RCV001240627]	uncertain significance	11	533608	533608	Human	1	name
126754241	CV994569	single nucleotide variant	NM_005343.4(HRAS):c.269T>C (p.Phe90Ser)	Costello syndrome [RCV001307584]\|not provided [RCV004779049]	uncertain significance	11	533787	533787	Human	1	name
126747196	CV994570	single nucleotide variant	NM_005343.4(HRAS):c.245T>C (p.Phe82Ser)	Costello syndrome [RCV001306208]	uncertain significance	11	533811	533811	Human	1	name
126751537	CV994571	single nucleotide variant	NM_005343.4(HRAS):c.138T>G (p.Ile46Met)	Costello syndrome [RCV001297540]	uncertain significance	11	533918	533918	Human	1	name
126739400	CV1009736	single nucleotide variant	NM_005343.4(HRAS):c.517C>T (p.Pro173Ser)	Costello syndrome [RCV001325045]\|not provided [RCV002466661]	uncertain significance	11	532689	532689	Human	1	name
126761276	CV1009737	single nucleotide variant	NM_005343.4(HRAS):c.497A>G (p.His166Arg)	Costello syndrome [RCV001318591]\|HRAS-related disorder [RCV003399099]	uncertain significance	11	532709	532709	Human	1	name , trait , alternate_id
126764072	CV1009738	single nucleotide variant	NM_005343.4(HRAS):c.479T>C (p.Val160Ala)	Costello syndrome [RCV001319495]	uncertain significance	11	532727	532727	Human	1	name
126767359	CV1009739	single nucleotide variant	NM_005343.4(HRAS):c.427G>A (p.Glu143Lys)	Costello syndrome [RCV001320813]	uncertain significance	11	533476	533476	Human	1	name
126769305	CV1009741	single nucleotide variant	NM_005343.4(HRAS):c.391C>G (p.Gln131Glu)	Costello syndrome [RCV001321875]	uncertain significance	11	533512	533512	Human	1	name
126737044	CV1009742	single nucleotide variant	NM_005343.4(HRAS):c.358C>G (p.Leu120Val)	Costello syndrome [RCV001324745]	uncertain significance	11	533545	533545	Human	1	name
126769005	CV1009743	single nucleotide variant	NM_005343.4(HRAS):c.307G>A (p.Val103Met)	Costello syndrome [RCV001321698]	uncertain significance	11	533596	533596	Human	1	name
126740263	CV1017461	single nucleotide variant	NM_005343.4(HRAS):c.386A>G (p.Gln129Arg)	Costello syndrome [RCV001329395]\|HRAS-related disorder [RCV005225372]\|not specified [RCV005419086]	conflicting interpretations of pathogenicity\|uncertain significance	11	533517	533517	Human	1	name , trait , alternate_id
126765018	CV1030297	single nucleotide variant	NM_005343.4(HRAS):c.545T>C (p.Met182Thr)	Costello syndrome [RCV001341872]	uncertain significance	11	532661	532661	Human	1	name
126773539	CV1030298	single nucleotide variant	NM_005343.4(HRAS):c.542G>A (p.Cys181Tyr)	Costello syndrome [RCV001346242]	uncertain significance	11	532664	532664	Human	1	name
126753485	CV1030299	single nucleotide variant	NM_005343.4(HRAS):c.506G>T (p.Arg169Leu)	Costello syndrome [RCV001338600]	uncertain significance	11	532700	532700	Human	1	name
126748226	CV1030300	single nucleotide variant	NM_005343.4(HRAS):c.484G>A (p.Glu162Lys)	Costello syndrome [RCV001337613]\|not provided [RCV001550317]	uncertain significance	11	532722	532722	Human	1	name
126748242	CV1030301	single nucleotide variant	NM_005343.4(HRAS):c.424A>G (p.Ile142Val)	Costello syndrome [RCV001351824]	uncertain significance	11	533479	533479	Human	1	name
126737710	CV1030302	single nucleotide variant	NM_005343.4(HRAS):c.379T>C (p.Ser127Pro)	Cardiovascular phenotype [RCV004036624]\|Costello syndrome [RCV001350388]	uncertain significance	11	533524	533524	Human	1	name
126746909	CV1030303	single nucleotide variant	NM_005343.4(HRAS):c.370A>G (p.Thr124Ala)	Cardiovascular phenotype [RCV005340829]\|Costello syndrome [RCV001351593]\|not provided [RCV002224077]	uncertain significance	11	533533	533533	Human	1	name
126753885	CV1030304	single nucleotide variant	NM_005343.4(HRAS):c.361G>A (p.Ala121Thr)	Costello syndrome [RCV001338691]\|Ovarian cancer [RCV003153999]	benign\|uncertain significance	11	533542	533542	Human	3	name
126916173	CV1047282	single nucleotide variant	NM_005343.4(HRAS):c.536C>T (p.Pro179Leu)	Costello syndrome [RCV001360423]\|not provided [RCV002269365]	uncertain significance	11	532670	532670	Human	1	name
126921912	CV1047283	single nucleotide variant	NM_005343.4(HRAS):c.515A>G (p.Asn172Ser)	Costello syndrome [RCV001364047]	uncertain significance	11	532691	532691	Human	1	name
126919337	CV1047284	single nucleotide variant	NM_005343.4(HRAS):c.463G>A (p.Ala155Thr)	Costello syndrome [RCV001373169]	uncertain significance	11	532743	532743	Human	1	name
126918930	CV1047285	single nucleotide variant	NM_005343.4(HRAS):c.329C>T (p.Pro110Leu)	Costello syndrome [RCV001372946]	uncertain significance	11	533574	533574	Human	1	name
150429000	CV1187757	single nucleotide variant	NM_005343.4(HRAS):c.468C>G (p.Phe156Leu)	not provided [RCV001563014]	pathogenic	11	532738	532738	Human		name
150543973	CV1310048	single nucleotide variant	NM_176795.5(HRAS):c.481G>A (p.Gly161Arg)	Costello syndrome [RCV005095098]\|not provided [RCV003238053]	likely benign\|uncertain significance	11	533328	533328	Human	1	name
150533930	CV1311376	single nucleotide variant	NM_005343.4(HRAS):c.454G>A (p.Val152Met)	Costello syndrome [RCV002541093]\|not provided [RCV001777111]	uncertain significance	11	532752	532752	Human	1	name
151234020	CV1318065	single nucleotide variant	NM_005343.4(HRAS):c.466T>C (p.Phe156Leu)	Costello syndrome [RCV001789705]	pathogenic	11	532740	532740	Human	1	name
151352137	CV1325101	single nucleotide variant	NM_005343.4(HRAS):c.521C>A (p.Pro174His)	Noonan syndrome and Noonan-related syndrome [RCV001813656]	uncertain significance	11	532685	532685	Human		name
151811769	CV1346809	single nucleotide variant	NM_005343.4(HRAS):c.362C>A (p.Ala121Asp)	Costello syndrome [RCV002048924]	uncertain significance	11	533541	533541	Human	1	name
151796281	CV1356002	single nucleotide variant	NM_005343.4(HRAS):c.368G>A (p.Arg123His)	Costello syndrome [RCV002027674]	uncertain significance	11	533535	533535	Human	1	name
151745714	CV1360987	single nucleotide variant	NM_005343.4(HRAS):c.425T>C (p.Ile142Thr)	Costello syndrome [RCV001871491]	uncertain significance	11	533478	533478	Human	1	name
151836745	CV1371354	single nucleotide variant	NM_005343.4(HRAS):c.365C>T (p.Ala122Val)	Costello syndrome [RCV001921064]	uncertain significance	11	533538	533538	Human	1	name
151805445	CV1371977	single nucleotide variant	NM_005343.4(HRAS):c.367C>G (p.Arg123Gly)	Costello syndrome [RCV001953316]	uncertain significance	11	533536	533536	Human	1	name
8687785	CV138253	single nucleotide variant	NM_005343.4(HRAS):c.473C>T (p.Thr158Met)	Costello syndrome [RCV000813562]\|not provided [RCV004696851]\|not specified [RCV000121201]	uncertain significance\|not provided	11	532733	532733	Human	1	name
151830409	CV1391672	single nucleotide variant	NM_005343.4(HRAS):c.476T>C (p.Leu159Ser)	Costello syndrome [RCV002050671]	uncertain significance	11	532730	532730	Human	1	name
151821173	CV1416320	single nucleotide variant	NM_005343.4(HRAS):c.535C>T (p.Pro179Ser)	Cardiovascular phenotype [RCV002344051]\|Costello syndrome [RCV001919589]\|not provided [RCV003159220]	uncertain significance	11	532671	532671	Human	1	name
151772243	CV1417959	single nucleotide variant	NM_005343.4(HRAS):c.551G>A (p.Cys184Tyr)	Costello syndrome [RCV001874567]	uncertain significance	11	532655	532655	Human	1	name
151856537	CV1422009	single nucleotide variant	NM_005343.4(HRAS):c.496C>T (p.His166Tyr)	Costello syndrome [RCV001938019]	uncertain significance	11	532710	532710	Human	1	name
151782158	CV1422238	single nucleotide variant	NM_005343.4(HRAS):c.364G>A (p.Ala122Thr)	Costello syndrome [RCV001972181]	uncertain significance	11	533539	533539	Human	1	name
151774387	CV1427942	single nucleotide variant	NM_005343.4(HRAS):c.400G>A (p.Ala134Thr)	Costello syndrome [RCV001915290]	uncertain significance	11	533503	533503	Human	1	name
151723704	CV1436896	single nucleotide variant	NM_005343.4(HRAS):c.429G>C (p.Glu143Asp)	Costello syndrome [RCV002004007]	uncertain significance	11	533474	533474	Human	1	name
151724649	CV1451974	single nucleotide variant	NM_005343.4(HRAS):c.307G>C (p.Val103Leu)	Costello syndrome [RCV002040529]	uncertain significance	11	533596	533596	Human	1	name
151872713	CV1467036	single nucleotide variant	NM_005343.4(HRAS):c.325G>A (p.Val109Met)	Costello syndrome [RCV001925424]	uncertain significance	11	533578	533578	Human	1	name
151797054	CV1467589	single nucleotide variant	NM_005343.4(HRAS):c.415A>T (p.Ile139Phe)	Costello syndrome [RCV001952572]	uncertain significance	11	533488	533488	Human	1	name
151753327	CV1471072	single nucleotide variant	NM_005343.4(HRAS):c.313G>A (p.Asp105Asn)	Costello syndrome [RCV001948371]	uncertain significance	11	533590	533590	Human	1	name
151889640	CV1479752	single nucleotide variant	NM_005343.4(HRAS):c.530G>A (p.Ser177Asn)	Costello syndrome [RCV001888222]	uncertain significance	11	532676	532676	Human	1	name
151809113	CV1483613	single nucleotide variant	NM_005343.4(HRAS):c.551G>C (p.Cys184Ser)	Costello syndrome [RCV001918427]	uncertain significance	11	532655	532655	Human	1	name
151854252	CV1485414	single nucleotide variant	NM_005343.4(HRAS):c.383G>T (p.Arg128Leu)	Costello syndrome [RCV002033573]	uncertain significance	11	533520	533520	Human	1	name
151751647	CV1508424	single nucleotide variant	NM_005343.4(HRAS):c.331A>G (p.Met111Val)	Costello syndrome [RCV001986343]	uncertain significance	11	533572	533572	Human	1	name
151758719	CV1510825	single nucleotide variant	NM_005343.4(HRAS):c.376G>C (p.Glu126Gln)	Costello syndrome [RCV001948892]	uncertain significance	11	533527	533527	Human	1	name
151733618	CV1512450	single nucleotide variant	NM_005343.4(HRAS):c.413G>T (p.Gly138Val)	Costello syndrome [RCV002021551]	uncertain significance	11	533490	533490	Human	1	name
153002332	CV1685330	single nucleotide variant	NM_005343.4(HRAS):c.481C>G (p.Arg161Gly)	Hereditary cancer-predisposing syndrome [RCV002258705]	uncertain significance	11	532725	532725	Human	1	name
9689141	CV174801	single nucleotide variant	NM_005343.4(HRAS):c.505C>T (p.Arg169Trp)	Cardiovascular phenotype [RCV002345496]\|Costello syndrome [RCV000803493]\|Large congenital melanocytic nevus [RCV002505170]\|not specified [RCV000154576]	uncertain significance	11	532701	532701	Human	14	name
9689080	CV175214	single nucleotide variant	NM_005343.4(HRAS):c.418C>T (p.Pro140Ser)	Costello syndrome [RCV000700279]\|not specified [RCV000154499]	likely benign\|uncertain significance	11	533485	533485	Human	1	name
155705445	CV1774975	single nucleotide variant	NM_005343.4(HRAS):c.530G>C (p.Ser177Thr)	Costello syndrome [RCV002300209]	uncertain significance	11	532676	532676	Human	1	name
155749055	CV1777213	single nucleotide variant	NM_005343.4(HRAS):c.559G>A (p.Val187Met)	Costello syndrome [RCV002304250]	uncertain significance	11	532647	532647	Human	1	name
155742325	CV1777221	single nucleotide variant	NM_005343.4(HRAS):c.484G>C (p.Glu162Gln)	Costello syndrome [RCV002302904]	uncertain significance	11	532722	532722	Human	1	name
155706794	CV1778380	single nucleotide variant	NM_005343.4(HRAS):c.325G>T (p.Val109Leu)	Costello syndrome [RCV002295996]	uncertain significance	11	533578	533578	Human	1	name
9832740	CV179411	single nucleotide variant	NM_005343.4(HRAS):c.544A>G (p.Met182Val)	Costello syndrome [RCV001219043]\|not provided [RCV000157924]	uncertain significance	11	532662	532662	Human	1	name
9832743	CV179412	single nucleotide variant	NM_005343.4(HRAS):c.506G>A (p.Arg169Gln)	Costello syndrome [RCV000463046]\|HRAS-related disorder [RCV003390855]\|Hereditary cancer-predisposing syndrome [RCV002258816]\|Large congenital melanocytic nevus [RCV002492617]\|not provided [RCV000505776]	uncertain significance	11	532700	532700	Human	15	name , trait , alternate_id
9832739	CV179413	single nucleotide variant	NM_005343.4(HRAS):c.368G>C (p.Arg123Pro)	Costello syndrome [RCV000533738]\|Hereditary cancer-predisposing syndrome [RCV002257459]	likely pathogenic\|uncertain significance	11	533535	533535	Human	2	name
9832738	CV179414	single nucleotide variant	NM_005343.4(HRAS):c.367C>T (p.Arg123Cys)	Costello syndrome [RCV000471505]\|Large congenital melanocytic nevus [RCV005049434]\|not provided [RCV000157922]\|not specified [RCV000606057]	likely pathogenic\|conflicting interpretations of pathogenicity\|uncertain significance	11	533536	533536	Human	7	name
9832742	CV179415	single nucleotide variant	NM_005343.4(HRAS):c.362C>T (p.Ala121Val)	Costello syndrome [RCV001850200]\|not provided [RCV000157927]	uncertain significance	11	533541	533541	Human	1	name
9832737	CV179416	single nucleotide variant	NM_005343.4(HRAS):c.317C>G (p.Ser106Trp)	Cardiovascular phenotype [RCV002321658]\|Costello syndrome [RCV000816581]\|not provided [RCV000157921]	uncertain significance	11	533586	533586	Human	1	name
155669278	CV1856277	single nucleotide variant	NM_005343.4(HRAS):c.302A>T (p.Lys101Ile)	Cardiovascular phenotype [RCV002435979]	uncertain significance	11	533601	533601	Human		name
156008542	CV1870627	single nucleotide variant	NM_005343.4(HRAS):c.473C>G (p.Thr158Arg)	Costello syndrome [RCV003076952]	uncertain significance	11	532733	532733	Human	1	name
156197205	CV1889813	single nucleotide variant	NM_005343.4(HRAS):c.451G>C (p.Gly151Arg)	Costello syndrome [RCV003084081]	uncertain significance	11	532755	532755	Human	1	name
156041509	CV1891072	single nucleotide variant	NM_005343.4(HRAS):c.403C>T (p.Arg135Ter)	Costello syndrome [RCV003078535]	uncertain significance	11	533500	533500	Human	1	name
156436132	CV1937351	single nucleotide variant	NM_005343.4(HRAS):c.424A>T (p.Ile142Phe)	Costello syndrome [RCV003105215]	uncertain significance	11	533479	533479	Human	1	name
156441484	CV1944141	single nucleotide variant	NM_005343.4(HRAS):c.489C>G (p.Ile163Met)	Costello syndrome [RCV003111810]	uncertain significance	11	532717	532717	Human	1	name
156445095	CV1945090	single nucleotide variant	NM_005343.4(HRAS):c.376G>T (p.Glu126Ter)	Costello syndrome [RCV003116030]	uncertain significance	11	533527	533527	Human	1	name
156415069	CV1965025	single nucleotide variant	NM_005343.4(HRAS):c.323A>G (p.Asp108Gly)	Costello syndrome [RCV002588959]	uncertain significance	11	533580	533580	Human	1	name
156272397	CV2004213	single nucleotide variant	NM_005343.4(HRAS):c.479T>G (p.Val160Gly)	Costello syndrome [RCV002646576]	uncertain significance	11	532727	532727	Human	1	name
156125026	CV2072697	single nucleotide variant	NM_005343.4(HRAS):c.518C>G (p.Pro173Arg)	Costello syndrome [RCV002825450]	likely benign	11	532688	532688	Human	1	name
156294983	CV2073432	single nucleotide variant	NM_005343.4(HRAS):c.406A>G (p.Ser136Gly)	Costello syndrome [RCV002833358]	uncertain significance	11	533497	533497	Human	1	name
156038742	CV2097878	single nucleotide variant	NM_005343.4(HRAS):c.446G>A (p.Arg149Gln)	Costello syndrome [RCV002885723]\|HRAS-related disorder [RCV003395528]	uncertain significance	11	533457	533457	Human	1	name , trait , alternate_id
156350316	CV2147053	single nucleotide variant	NM_005343.4(HRAS):c.486G>C (p.Glu162Asp)	Costello syndrome [RCV003030820]	uncertain significance	11	532720	532720	Human	1	name
155996255	CV2156557	single nucleotide variant	NM_005343.4(HRAS):c.451G>A (p.Gly151Arg)	Costello syndrome [RCV002996801]	uncertain significance	11	532755	532755	Human	1	name
156187878	CV2178783	single nucleotide variant	NM_005343.4(HRAS):c.477G>T (p.Leu159Phe)	Costello syndrome [RCV003057735]	uncertain significance	11	532729	532729	Human	1	name
156297813	CV2180457	single nucleotide variant	NM_005343.4(HRAS):c.319G>A (p.Asp107Asn)	Costello syndrome [RCV003027950]	uncertain significance	11	533584	533584	Human	1	name
156096507	CV2183587	single nucleotide variant	NM_005343.4(HRAS):c.313G>C (p.Asp105His)	Costello syndrome [RCV003054560]	uncertain significance	11	533590	533590	Human	1	name
11349040	CV241153	single nucleotide variant	NM_005343.4(HRAS):c.546G>A (p.Met182Ile)	Costello syndrome [RCV000229010]\|Large congenital melanocytic nevus [RCV005049496]\|not specified [RCV003993902]	likely benign\|uncertain significance	11	532660	532660	Human	7	name
11346394	CV241154	single nucleotide variant	NM_005343.4(HRAS):c.498C>A (p.His166Gln)	Costello syndrome [RCV000228331]	likely benign\|uncertain significance	11	532708	532708	Human	1	name
8599072	CV27644	single nucleotide variant	NM_005343.4(HRAS):c.350A>G (p.Lys117Arg)	Costello syndrome [RCV000013439]\|RASopathy [RCV005252033]\|not provided [RCV000353386]	pathogenic	11	533553	533553	Human	2	name
8563227	CV27646	single nucleotide variant	NM_005343.4(HRAS):c.436G>A (p.Ala146Thr)	Costello syndrome [RCV000013441]	pathogenic\|likely pathogenic	11	533467	533467	Human	1	name
8563230	CV27650	single nucleotide variant	NM_005343.4(HRAS):c.437C>T (p.Ala146Val)	Costello syndrome [RCV000013445]	pathogenic\|likely pathogenic\|conflicting interpretations of pathogenicity\|conflicting data from submitters	11	533466	533466	Human	1	name
405015639	CV2855339	single nucleotide variant	NM_005343.4(HRAS):c.538G>C (p.Gly180Arg)	Costello syndrome [RCV003515374]	uncertain significance	11	532668	532668	Human	1	name
405016735	CV2857004	single nucleotide variant	NM_005343.4(HRAS):c.407G>C (p.Ser136Thr)	Costello syndrome [RCV003515519]	uncertain significance	11	533496	533496	Human	1	name
405008048	CV2857078	single nucleotide variant	NM_005343.4(HRAS):c.511C>G (p.Leu171Val)	Costello syndrome [RCV003514672]	uncertain significance	11	532695	532695	Human	1	name
405018047	CV2878215	single nucleotide variant	NM_005343.4(HRAS):c.532G>A (p.Gly178Ser)	Costello syndrome [RCV003515621]	uncertain significance	11	532674	532674	Human	1	name
402496660	CV2975403	single nucleotide variant	NM_005343.4(HRAS):c.457G>T (p.Glu153Ter)	Costello syndrome [RCV003627822]	uncertain significance	11	532749	532749	Human	1	name
402498350	CV2980814	single nucleotide variant	NM_005343.4(HRAS):c.460G>T (p.Asp154Tyr)	Costello syndrome [RCV003627913]	likely benign	11	532746	532746	Human	1	name
402497975	CV2981445	single nucleotide variant	NM_005343.4(HRAS):c.516C>A (p.Asn172Lys)	Costello syndrome [RCV003627985]	uncertain significance	11	532690	532690	Human	1	name
402498221	CV2988428	single nucleotide variant	NM_005343.4(HRAS):c.493C>A (p.Gln165Lys)	Costello syndrome [RCV003628010]	uncertain significance	11	532713	532713	Human	1	name
402499217	CV2989560	single nucleotide variant	NM_005343.4(HRAS):c.305G>A (p.Arg102Gln)	Costello syndrome [RCV003628118]	uncertain significance	11	533598	533598	Human	1	name
402503591	CV3013374	single nucleotide variant	NM_005343.4(HRAS):c.395A>G (p.Asp132Gly)	Costello syndrome [RCV003628575]	uncertain significance	11	533508	533508	Human	1	name
402490971	CV3045797	single nucleotide variant	NM_005343.4(HRAS):c.443C>G (p.Thr148Ser)	Costello syndrome [RCV003627211]	uncertain significance	11	533460	533460	Human	1	name
402490650	CV3054995	single nucleotide variant	NM_005343.4(HRAS):c.374T>G (p.Val125Gly)	Costello syndrome [RCV003627154]	uncertain significance	11	533529	533529	Human	1	name
402491304	CV3066855	single nucleotide variant	NM_005343.4(HRAS):c.412G>C (p.Gly138Arg)	Costello syndrome [RCV003627248]	uncertain significance	11	533491	533491	Human	1	name
405181744	CV3119991	single nucleotide variant	NM_005343.4(HRAS):c.347A>G (p.Asn116Ser)	Costello syndrome [RCV003820084]	uncertain significance	11	533556	533556	Human	1	name
405143425	CV3126074	single nucleotide variant	NM_005343.4(HRAS):c.331A>T (p.Met111Leu)	Cardiovascular phenotype [RCV004366729]\|Costello syndrome [RCV003816990]	uncertain significance	11	533572	533572	Human	1	name
405160217	CV3152949	single nucleotide variant	NM_005343.4(HRAS):c.343G>A (p.Gly115Arg)	Costello syndrome [RCV003840684]	uncertain significance	11	533560	533560	Human	1	name
405253520	CV3174498	single nucleotide variant	NM_005343.4(HRAS):c.473C>A (p.Thr158Lys)	Costello syndrome [RCV003871128]	uncertain significance	11	532733	532733	Human	1	name
405262238	CV3194421	single nucleotide variant	NM_005343.4(HRAS):c.434C>T (p.Ser145Leu)	HRAS-related disorder [RCV003896450]	uncertain significance	11	533469	533469	Human		name , trait , alternate_id
405289979	CV3214047	single nucleotide variant	NM_176795.5(HRAS):c.457C>T (p.Arg153Cys)	HRAS-related disorder [RCV003926889]	likely benign	11	533352	533352	Human		name , trait , alternate_id
407425171	CV3411142	single nucleotide variant	NM_005343.4(HRAS):c.389C>T (p.Ala130Val)	not provided [RCV004588832]	uncertain significance	11	533514	533514	Human		name
407528315	CV3433919	single nucleotide variant	NM_005343.4(HRAS):c.478G>C (p.Val160Leu)	Cardiovascular phenotype [RCV004633108]	uncertain significance	11	532728	532728	Human		name
596929787	CV3531152	single nucleotide variant	NM_005343.4(HRAS):c.403C>G (p.Arg135Gly)	not provided [RCV004779726]	uncertain significance	11	533500	533500	Human		name
12741261	CV360035	single nucleotide variant	NM_005343.4(HRAS):c.304C>T (p.Arg102Trp)	Costello syndrome [RCV001369972]\|not specified [RCV000414564]	uncertain significance	11	533599	533599	Human	1	name
12834386	CV363321	single nucleotide variant	NM_005343.4(HRAS):c.436G>C (p.Ala146Pro)	Acute myeloid leukemia [RCV000417704]\|Gastric adenocarcinoma [RCV000439704]\|Lung adenocarcinoma [RCV000439018]\|Multiple myeloma [RCV000429488]\|Neoplasm of the large intestine [RCV000427905]\|Neoplasm of uterine cervix [RCV000418346]	likely pathogenic	11	533467	533467	Human	5	name
597725414	CV3729987	single nucleotide variant	NM_005343.4(HRAS):c.550T>G (p.Cys184Gly)	Large congenital melanocytic nevus [RCV005050243]	uncertain significance	11	532656	532656	Human	6	name
597836051	CV3764477	single nucleotide variant	NM_005343.4(HRAS):c.500A>G (p.Lys167Arg)	Costello syndrome [RCV005107277]	uncertain significance	11	532706	532706	Human	1	name
597836055	CV3764478	single nucleotide variant	NM_005343.4(HRAS):c.446G>T (p.Arg149Leu)	Costello syndrome [RCV005107278]	uncertain significance	11	533457	533457	Human	1	name
597836059	CV3764480	single nucleotide variant	NM_005343.4(HRAS):c.377A>G (p.Glu126Gly)	Costello syndrome [RCV005107280]	uncertain significance	11	533526	533526	Human	1	name
597836162	CV3764617	single nucleotide variant	NM_005343.4(HRAS):c.509A>G (p.Lys170Arg)	Costello syndrome [RCV005107416]	uncertain significance	11	532697	532697	Human	1	name
597878178	CV3803924	single nucleotide variant	NM_005343.4(HRAS):c.340G>A (p.Val114Met)	Costello syndrome [RCV005153469]	uncertain significance	11	533563	533563	Human	1	name
12890815	CV398678	single nucleotide variant	NM_005343.4(HRAS):c.391C>T (p.Gln131Ter)	Costello syndrome [RCV000475366]\|Large congenital melanocytic nevus [RCV005049560]\|not provided [RCV002464203]	uncertain significance	11	533512	533512	Human	7	name
12880860	CV398759	single nucleotide variant	NM_005343.4(HRAS):c.398T>A (p.Leu133His)	Cardiovascular phenotype [RCV002374788]\|Costello syndrome [RCV000456787]\|Linear nevus sebaceous syndrome [RCV001535653]\|not provided [RCV000681068]\|not specified [RCV003151066]	uncertain significance\|not provided	11	533505	533505	Human	4	name
12892034	CV398760	single nucleotide variant	NM_005343.4(HRAS):c.317C>T (p.Ser106Leu)	Costello syndrome [RCV000469881]	uncertain significance	11	533586	533586	Human	1	name
617152957	CV4018513	single nucleotide variant	NM_005343.4(HRAS):c.326T>C (p.Val109Ala)	not specified [RCV005418774]	uncertain significance	11	533577	533577	Human		name
12898552	CV408384	single nucleotide variant	NM_005343.4(HRAS):c.448C>T (p.Gln150Ter)	not provided [RCV000478173]	uncertain significance	11	533455	533455	Human		name
12913615	CV421862	single nucleotide variant	NM_005343.4(HRAS):c.302A>G (p.Lys101Arg)	Costello syndrome [RCV000705122]\|not provided [RCV000494039]	likely benign\|uncertain significance	11	533601	533601	Human	1	name
13475520	CV461199	single nucleotide variant	NM_005343.4(HRAS):c.518C>T (p.Pro173Leu)	Costello syndrome [RCV000526328]\|Intellectual disability [RCV001260727]	uncertain significance	11	532688	532688	Human	3	name
13494370	CV461389	single nucleotide variant	NM_005343.4(HRAS):c.413G>A (p.Gly138Asp)	Costello syndrome [RCV000558860]	uncertain significance	11	533490	533490	Human	1	name
13474758	CV461709	single nucleotide variant	NM_005343.4(HRAS):c.452G>C (p.Gly151Ala)	Costello syndrome [RCV000525978]	uncertain significance	11	532754	532754	Human	1	name
9832732	CV48914	single nucleotide variant	NM_176795.5(HRAS):c.500C>T (p.Pro167Leu)	not specified [RCV000157908]	likely benign	11	533309	533309	Human		name
12842476	CV48915	single nucleotide variant	NM_005343.4(HRAS):c.460G>A (p.Asp154Asn)	Costello syndrome [RCV000637302]\|not provided [RCV000434487]	likely benign\|conflicting interpretations of pathogenicity\|uncertain significance	11	532746	532746	Human	1	name
9832733	CV48917	single nucleotide variant	NM_005343.4(HRAS):c.508A>T (p.Lys170Ter)	Costello syndrome [RCV000551172]\|Large congenital melanocytic nevus [RCV002477044]\|not provided [RCV000157909]	likely benign\|uncertain significance	11	532698	532698	Human	7	name
8608146	CV48918	single nucleotide variant	NM_005343.4(HRAS):c.520C>T (p.Pro174Ser)	Costello syndrome [RCV000234040]\|HRAS-related disorder [RCV003944865]\|Hereditary cancer-predisposing syndrome [RCV002258783]\|Large congenital melanocytic nevus [RCV000755642]\|RASopathy [RCV000520658]\|not specified [RCV000038467]	benign\|likely benign\|conflicting interpretations of pathogenicity\|uncertain significance	11	532686	532686	Human	16	name , trait , alternate_id
13516382	CV494969	single nucleotide variant	NM_005343.4(HRAS):c.445C>T (p.Arg149Trp)	Costello syndrome [RCV000700035]\|not provided [RCV000681102]\|not specified [RCV000595459]	uncertain significance	11	533458	533458	Human	1	name
13542050	CV497621	single nucleotide variant	NM_005343.4(HRAS):c.482G>A (p.Arg161His)	Costello syndrome [RCV001202259]\|not specified [RCV000616994]	uncertain significance	11	532724	532724	Human	1	name
13605868	CV526484	single nucleotide variant	NM_005343.4(HRAS):c.383G>C (p.Arg128Pro)	Costello syndrome [RCV000637305]	uncertain significance	11	533520	533520	Human	1	name
13605866	CV526759	single nucleotide variant	NM_005343.4(HRAS):c.397C>T (p.Leu133Phe)	Cardiovascular phenotype [RCV002358789]\|Costello syndrome [RCV000637303]	likely benign\|uncertain significance	11	533506	533506	Human	1	name
8608142	CV54470	single nucleotide variant	NM_005343.4(HRAS):c.401C>T (p.Ala134Val)	Costello syndrome [RCV000230783]\|not specified [RCV000038463]	uncertain significance	11	533502	533502	Human	1	name
8608143	CV54471	single nucleotide variant	NM_005343.4(HRAS):c.412G>A (p.Gly138Ser)	Cardiovascular phenotype [RCV004018874]\|Costello syndrome [RCV000548489]\|HRAS-related disorder [RCV003421952]\|Hereditary cancer-predisposing syndrome [RCV002257383]\|Large congenital melanocytic nevus [RCV005049407]\|RASopathy [RCV001030071]\|not provided [RCV00068 ... (more) 1055]\|not specified [RCV000038464]	likely benign\|uncertain significance	11	533491	533491	Human	16	name , trait , alternate_id
13811430	CV564738	single nucleotide variant	NM_005343.4(HRAS):c.490C>T (p.Arg164Trp)	Costello syndrome [RCV000703060]\|Hereditary cancer-predisposing syndrome [RCV002259010]\|not specified [RCV005240496]	uncertain significance	11	532716	532716	Human	2	name
13808523	CV564743	single nucleotide variant	NM_005343.4(HRAS):c.394G>A (p.Asp132Asn)	Costello syndrome [RCV000687312]\|not provided [RCV000788501]\|not specified [RCV004782512]	uncertain significance	11	533509	533509	Human	1	name
13818263	CV564745	single nucleotide variant	NM_005343.4(HRAS):c.388G>C (p.Ala130Pro)	Costello syndrome [RCV000707594]	conflicting interpretations of pathogenicity\|uncertain significance	11	533515	533515	Human	1	name
13812286	CV564747	single nucleotide variant	NM_005343.4(HRAS):c.332T>C (p.Met111Thr)	Costello syndrome [RCV000689351]	uncertain significance	11	533571	533571	Human	1	name
13813479	CV567334	single nucleotide variant	NM_005343.4(HRAS):c.487A>T (p.Ile163Phe)	Costello syndrome [RCV000704391]	uncertain significance	11	532719	532719	Human	1	name
13808420	CV567338	single nucleotide variant	NM_005343.4(HRAS):c.461A>T (p.Asp154Val)	Costello syndrome [RCV000701626]\|HRAS-related disorder [RCV003892562]	uncertain significance	11	532745	532745	Human	1	name , trait , alternate_id
13822164	CV567341	single nucleotide variant	NM_005343.4(HRAS):c.424A>C (p.Ile142Leu)	Costello syndrome [RCV000696822]	uncertain significance	11	533479	533479	Human	1	name
14712188	CV640150	single nucleotide variant	NM_005343.4(HRAS):c.538G>A (p.Gly180Ser)	Costello syndrome [RCV000810206]\|not provided [RCV002269317]	uncertain significance	11	532668	532668	Human	1	name
14731302	CV640151	single nucleotide variant	NM_005343.4(HRAS):c.532G>C (p.Gly178Arg)	Costello syndrome [RCV000817769]	uncertain significance	11	532674	532674	Human	1	name
14721250	CV640152	single nucleotide variant	NM_005343.4(HRAS):c.520C>G (p.Pro174Ala)	Costello syndrome [RCV000797018]\|Noonan syndrome [RCV001261054]	uncertain significance	11	532686	532686	Human	2	name
14723235	CV640153	single nucleotide variant	NM_005343.4(HRAS):c.481C>T (p.Arg161Cys)	Costello syndrome [RCV000797879]\|Large congenital melanocytic nevus [RCV002501060]\|not provided [RCV001592979]	uncertain significance	11	532725	532725	Human	7	name
14706147	CV640154	single nucleotide variant	NM_005343.4(HRAS):c.382C>T (p.Arg128Trp)	Costello syndrome [RCV000791901]	uncertain significance	11	533521	533521	Human	1	name
15136997	CV738027	single nucleotide variant	NM_005343.4(HRAS):c.535C>G (p.Pro179Ala)	Costello syndrome [RCV000898724]	likely benign	11	532671	532671	Human	1	name
26922167	CV838558	single nucleotide variant	NM_005343.4(HRAS):c.565T>G (p.Ser189Ala)	Costello syndrome [RCV001061654]	uncertain significance	11	532641	532641	Human	1	name
26905952	CV838559	single nucleotide variant	NM_005343.4(HRAS):c.548G>A (p.Ser183Asn)	Costello syndrome [RCV001037216]\|Noonan syndrome [RCV001261055]	likely benign\|uncertain significance	11	532658	532658	Human	2	name
26913938	CV838560	single nucleotide variant	NM_005343.4(HRAS):c.491G>C (p.Arg164Pro)	Costello syndrome [RCV001054590]\|Large congenital melanocytic nevus [RCV002481991]	uncertain significance	11	532715	532715	Human	7	name
26913173	CV838561	single nucleotide variant	NM_005343.4(HRAS):c.422A>G (p.Tyr141Cys)	Costello syndrome [RCV001039872]\|Hereditary cancer-predisposing syndrome [RCV002258094]	uncertain significance	11	533481	533481	Human	2	name
26905185	CV838562	single nucleotide variant	NM_005343.4(HRAS):c.410A>C (p.Tyr137Ser)	Cardiovascular phenotype [RCV002320236]\|Costello syndrome [RCV001036900]\|Large congenital melanocytic nevus [RCV002505558]	uncertain significance	11	533493	533493	Human	14	name
26889422	CV838566	microsatellite	NM_005343.4(HRAS):c.17TGG[3] (p.Val9del)	Costello syndrome [RCV001067470]	uncertain significance	11	534295	534297	Human		name
38481252	CV926270	single nucleotide variant	NM_005343.4(HRAS):c.544A>C (p.Met182Leu)	Costello syndrome [RCV001217922]	uncertain significance	11	532662	532662	Human	1	name
38485038	CV926271	single nucleotide variant	NM_005343.4(HRAS):c.539G>A (p.Gly180Asp)	Costello syndrome [RCV001219695]	uncertain significance	11	532667	532667	Human	1	name
38484446	CV926272	single nucleotide variant	NM_005343.4(HRAS):c.491G>A (p.Arg164Gln)	Costello syndrome [RCV001219438]\|HRAS-related disorder [RCV003398958]\|not provided [RCV001776147]	conflicting interpretations of pathogenicity\|uncertain significance	11	532715	532715	Human	1	name , trait , alternate_id
38489881	CV935593	single nucleotide variant	NM_005343.4(HRAS):c.566C>T (p.Ser189Phe)	Costello syndrome [RCV001210405]	uncertain significance	11	532640	532640	Human	1	name
38474054	CV935594	single nucleotide variant	NM_005343.4(HRAS):c.503T>C (p.Leu168Pro)	Costello syndrome [RCV001203653]\|Noonan syndrome and Noonan-related syndrome [RCV001813581]\|not provided [RCV004697069]	uncertain significance	11	532703	532703	Human	1	name
38478725	CV935595	single nucleotide variant	NM_005343.4(HRAS):c.463G>T (p.Ala155Ser)	Costello syndrome [RCV001205671]	uncertain significance	11	532743	532743	Human	1	name
38477031	CV935596	single nucleotide variant	NM_005343.4(HRAS):c.426C>G (p.Ile142Met)	Cardiovascular phenotype [RCV002327468]\|Costello syndrome [RCV001204909]	uncertain significance	11	533477	533477	Human	1	name
38486161	CV935597	single nucleotide variant	NM_005343.4(HRAS):c.407G>A (p.Ser136Asn)	Costello syndrome [RCV001208775]	uncertain significance	11	533496	533496	Human	1	name
38496820	CV947499	single nucleotide variant	NM_005343.4(HRAS):c.427G>C (p.Glu143Gln)	Costello syndrome [RCV001226647]\|not provided [RCV004768941]	uncertain significance	11	533476	533476	Human	1	name
38475724	CV947500	single nucleotide variant	NM_005343.4(HRAS):c.419C>T (p.Pro140Leu)	Cardiovascular phenotype [RCV004033178]\|Costello syndrome [RCV001232757]	uncertain significance	11	533484	533484	Human	1	name
38480442	CV947501	single nucleotide variant	NM_005343.4(HRAS):c.383G>A (p.Arg128Gln)	Costello syndrome [RCV001234711]	uncertain significance	11	533520	533520	Human	1	name
38490571	CV956531	single nucleotide variant	NM_005343.4(HRAS):c.464C>T (p.Ala155Val)	Costello syndrome [RCV001238905]	uncertain significance	11	532742	532742	Human	1	name
40813850	CV969664	single nucleotide variant	NM_005343.4(HRAS):c.374T>C (p.Val125Ala)	Costello syndrome [RCV001880001]\|Noonan syndrome [RCV001261052]	uncertain significance	11	533529	533529	Human	2	name
126760876	CV994565	single nucleotide variant	NM_005343.4(HRAS):c.560T>C (p.Val187Ala)	Costello syndrome [RCV001309436]	uncertain significance	11	532646	532646	Human	1	name
126740947	CV994566	single nucleotide variant	NM_005343.4(HRAS):c.469T>C (p.Tyr157His)	Costello syndrome [RCV001305343]	uncertain significance	11	532737	532737	Human	1	name
126755872	CV994567	single nucleotide variant	NM_005343.4(HRAS):c.404G>A (p.Arg135Gln)	Costello syndrome [RCV001298446]	uncertain significance	11	533499	533499	Human	1	name
152157101	CV1668962	inversion	NM_005343.4(HRAS):c.37_38inv (p.Gly13Pro)	not specified [RCV002223171]	uncertain significance	11	534285	534286	Human		name
13519671	CV487315	duplication	NM_005343.4(HRAS):c.27_29dup (p.Gly10dup)	not provided [RCV000586325]	uncertain significance	11	534293	534294	Human		name
11349237	CV241157	deletion	NM_005343.4(HRAS):c.174_192del (p.Gly60fs)	Costello syndrome [RCV000229731]	uncertain significance	11	533864	533882	Human	1	name
14702867	CV653975	duplication	NM_005343.4(HRAS):c.188_230dup (p.Phe78fs)	Costello syndrome [RCV000824932]	uncertain significance	11	533825	533826	Human	1	name
150557220	CV1311425	deletion	NM_176795.5(HRAS):c.488_497del (p.Leu163fs)	Costello syndrome [RCV001775533]\|not provided [RCV005057609]	pathogenic\|likely pathogenic	11	533312	533321	Human	1	name
151742562	CV1431636	deletion	NM_005343.4(HRAS):c.474_475del (p.Leu159fs)	Costello syndrome [RCV001926608]	uncertain significance	11	532731	532732	Human		name
155643740	CV1709536	indel	NM_005343.4(HRAS):c.149delinsGA (p.Thr50fs)	Prostate cancer, hereditary, 1 [RCV002292419]	uncertain significance	11	533907	533907	Human		name
155643742	CV1709538	insertion	NM_005343.4(HRAS):c.144_145insC (p.Glu49fs)	Prostate cancer, hereditary, 1 [RCV002292421]	uncertain significance	11	533911	533912	Human	1	name
156293598	CV1883952	microsatellite	NM_005343.4(HRAS):c.529_530del (p.Ser177fs)	Costello syndrome [RCV003087592]	uncertain significance	11	532676	532677	Human		name
155928557	CV2095878	duplication	NM_005343.4(HRAS):c.177_433dup (p.Glu98Ter)	Costello syndrome [RCV002903700]	uncertain significance	11	533463	533464	Human	1	name
8568001	CV38867	duplication	NM_005343.4(HRAS):c.108_110dup (p.Glu37dup)	Costello syndrome [RCV000022798]	pathogenic	11	534212	534213	Human	1	name
26887811	CV818441	deletion	NM_176795.5(HRAS):c.488_507del (p.Leu163fs)	Costello syndrome [RCV003514457]\|HRAS-related disorder [RCV003928669]\|RASopathy [RCV001030086]\|not provided [RCV001619882]	benign\|likely benign	11	533302	533321	Human	2	name , trait , alternate_id
38492752	CV926273	deletion	NM_005343.4(HRAS):c.412_431del (p.Gly138fs)	Costello syndrome [RCV001223776]	uncertain significance	11	533472	533491	Human	1	name
155937438	CV2075029	deletion	NM_005343.4(HRAS):c.529_531del (p.Ser177del)	Costello syndrome [RCV002861544]	uncertain significance	11	532675	532677	Human	1	name
156182077	CV2155636	deletion	NM_005343.4(HRAS):c.566_568del (p.Ser189del)	Costello syndrome [RCV003005736]	uncertain significance	11	532638	532640	Human	1	name
405026268	CV2901931	deletion	NM_005343.4(HRAS):c.424_426del (p.Ile142del)	Costello syndrome [RCV003516394]	uncertain significance	11	533477	533479	Human	1	name
155967986	CV2077024	deletion	NM_005343.4(HRAS):c.16_24del (p.Leu6_Val8del)	Costello syndrome [RCV002863174]	uncertain significance	11	534299	534307	Human	1	name
9691716	CV174805	indel	NM_005343.4(HRAS):c.35_36delinsAA (p.Gly12Glu)	Costello syndrome [RCV000150836]\|not provided [RCV000255809]	pathogenic\|likely pathogenic	11	534287	534288	Human		name
9832741	CV179420	indel	NM_005343.4(HRAS):c.35_36delinsAT (p.Gly12Asp)	not provided [RCV001678586]	pathogenic	11	534287	534288	Human		name
11580093	CV264557	indel	NM_005343.4(HRAS):c.35_36delinsTA (p.Gly12Val)	not provided [RCV000322736]	pathogenic	11	534287	534288	Human		name
9832744	CV48900	indel	NM_005343.4(HRAS):c.35_36delinsCT (p.Gly12Ala)	not provided [RCV000157929]	pathogenic	11	534287	534288	Human		name
150420863	CV613672	indel	NM_005343.4(HRAS):c.35_36delinsTT (p.Gly12Val)	Costello syndrome [RCV001732216]\|not provided [RCV001577794]	pathogenic	11	534287	534288	Human		name
405241331	CV3176927	indel	NM_005343.4(HRAS):c.473_475delinsG (p.Thr158fs)	Costello syndrome [RCV003867366]	uncertain significance	11	532731	532733	Human		name
9690372	CV174803	indel	NM_005343.4(HRAS):c.175_176delinsCT (p.Ala59Leu)	Costello syndrome [RCV000156047]	likely pathogenic	11	533880	533881	Human		name
12848498	CV363199	indel	NM_005343.4(HRAS):c.182_183delinsGT (p.Gln61Arg)	Neoplasm [RCV000435225]	likely pathogenic	11	533873	533874	Human		name
12848477	CV363200	indel	NM_005343.4(HRAS):c.182_183delinsGA (p.Gln61Arg)	Neoplasm [RCV000418005]	likely pathogenic	11	533873	533874	Human		name
8591083	CV125817	duplication	NM_005343.4(HRAS):c.187_207dup (p.Glu63_Asp69dup)	Costello syndrome [RCV000106320]	pathogenic	11	533848	533849	Human	1	name
151804627	CV1429750	duplication	NM_005343.4(HRAS):c.171_185dup (p.Asp57_Gln61dup)	Costello syndrome [RCV001974222]	likely pathogenic\|uncertain significance	11	533870	533871	Human	1	name
13503811	CV461391	duplication	NM_005343.4(HRAS):c.186_206dup (p.Glu62_Arg68dup)	Costello syndrome [RCV000546898]	pathogenic\|likely pathogenic\|uncertain significance	11	533849	533850	Human	1	name
151757979	CV1443593	deletion	NM_005343.4(HRAS):c.482_511del (p.Arg161_Lys170del)	Costello syndrome [RCV001872917]	uncertain significance	11	532695	532724	Human	1	name
40813851	CV969663	duplication	NM_176795.5(HRAS):c.463_468dup (p.Gly155_Ser156dup)	Noonan syndrome [RCV001261053]	uncertain significance	11	533340	533341	Human	1	name
155982050	CV2090603	insertion	NM_005343.4(HRAS):c.401_402insAAGACCTCGC (p.Ser136fs)	Costello syndrome [RCV002881981]	uncertain significance	11	533501	533502	Human	1	name
407574679	CV3495427	duplication	NM_005343.4(HRAS):c.197_217dup (p.Met72_Arg73insProMetArgAspGlnTyrMet)	HRAS-related disorder [RCV004720184]\|Vascular malformation [RCV005251391]	pathogenic\|likely pathogenic	11	533838	533839	Human	1	name , trait , alternate_id
153000855	CV1683854	duplication	NM_005343.4(HRAS):c.191_217dup (p.Met72_Arg73insHisSerAlaMetArgAspGlnTyrMet)	not provided [RCV002254473]	likely pathogenic	11	533838	533839	Human		name
401914244	CV2799113	duplication	NM_005343.4(HRAS):c.179_205dup (p.Arg68_Asp69insGlyGlnGluGluTyrSerAlaMetArg)	HRAS-related disorder [RCV003400256]	likely pathogenic	11	533850	533851	Human		name , trait , alternate_id
153000856	CV1683855	duplication	NM_005343.4(HRAS):c.191_220dup (p.Arg73_Thr74insAsnSerAlaMetArgAspGlnTyrMetArg)	not provided [RCV002254474]	likely pathogenic	11	533835	533836	Human		name
407574682	CV3495431	duplication	NM_005343.4(HRAS):c.203_232dup (p.Gly77_Phe78insTrpAspGlnTyrMetArgThrGlyGluGly)	HRAS-related disorder [RCV004720187]	pathogenic	11	533823	533824	Human		name , trait , alternate_id
15112400	CV677975	indel	NM_005343.4(HRAS):c.172_177delinsGTCCTGGATGTT (p.Thr58_Ala59delinsValLeuAspVal)	Arteriovenous malformation [RCV000860022]	pathogenic	11	533879	533884	Human		name
34896632	CV917090	insertion	NM_005343.4(HRAS):c.165_166insTCCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATC (p.Leu56fs)	not specified [RCV001194132]	uncertain significance	11	533890	533891	Human		name
598214615	CV3890653	insertion	NM_005343.4(HRAS):c.208_209insGGTGGTACAGCGCCATGCGGGACC (p.Asp69_Gln70insArgTrpTyrSerAlaMetArgAsp)	Arteriovenous malformation [RCV005251531]	likely pathogenic	11	533847	533848	Human	2	name
405869355	CV3397747	insertion	NM_005343.4(HRAS):c.215_216insCTCCAGCGCCATGCGGGACCAGTACAT (p.Tyr71_Met72insIleSerSerAlaMetArgAspGlnTyr)	Vascular malformation [RCV004566498]	likely pathogenic	11	533840	533841	Human	1	name
598214587	CV3890641	insertion	NM_005343.4(HRAS):c.216_217insAACAGCGCCATGCGGGACCAGTACATG (p.Met72_Arg73insAsnSerAlaMetArgAspGlnTyrMet)	Vascular malformation [RCV005251519]	likely pathogenic	11	533839	533840	Human	1	name
8634264	CV89482	single nucleotide variant	HRASLS5:c.605G>A	Malignant melanoma [RCV000069579]	not provided	11	63466252	63466252	Human		name
8630735	CV85890	single nucleotide variant	NM_020386.4(HRASLS):c.400C>T (p.Gln134Ter)	Malignant melanoma [RCV000065974]	not provided	3	193255735	193255735	Human		name
8630736	CV85891	single nucleotide variant	NM_020386.4(HRASLS):c.793C>T (p.Pro265Ser)	Malignant melanoma [RCV000065975]	not provided	3	193270676	193270676	Human		name

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