Kcnn2 Strain Search Result - Rat Genome Database

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1 records found for search term Kcnn2

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RGD ID	Symbol	Name	Origin	Source	Type	Annotations	Match
2314368	F344-Kcnn2^Trdk/Kyo	Tremor dominant Kyoto	Tremor dominant Kyoto (Trdk) mutation is an autosomal dominant mutation that appeared in 2008 in a stock of F344/NSlc rats that had been mutagenized with N-ethyl-N-nitrosourea (ENU) (Mashimo et al., 2008). Rats heterozygous for Trdk (Trdk/+) exhibited tremor behavior that was evident around weaning. ... (more) To remove latent ENU-induced mutations, the laboratory established an F344-Trdk/+ congenic strain by nine rounds of backcrossing. Using positional candidate approach, Trdk mutation was identified as a missense substitution (c. 866 T > A, p. I289N) in Kcnn2.	National BioResource Project for the Rat in Japan	mutant	3	symbol , origin